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TULP3 [cilium]
Stable Identifier
R-HSA-5610445
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cilium
Locations in the PathwayBrowser for interactor UniProt:O95376 ARIH2
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'off' state (Homo sapiens)
The IFT-A complex recruits TULP3 (Homo sapiens)
TULP3 [cilium] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75386 TULP3
Gene Names
TULP3, TUBL3
Chain
chain:1-442
Reference Genes
BioGPS Gene:7289 TULP3
COSMIC (genes):TULP3 TULP3
CTD Gene:7289 TULP3
dbSNP Gene:7289 TULP3
ENSEMBL:ENSG00000078246 TULP3
ENSEMBL_homo_sapiens_GENE:ENSG00000078246.17 TULP3
HGNC:12425 TULP3
KEGG Gene (Homo sapiens):7289 TULP3
Monarch:7289 TULP3
NCBI Gene:7289 TULP3
OMIM:604730 TULP3
UCSC:O75386 TULP3
Reference Transcript
RefSeq:NM_001160408.1 TULP3
RefSeq:NM_003324.4 TULP3
Other Identifiers
11739643_a_at
11739644_a_at
11739645_x_at
11739646_a_at
11748397_x_at
11751660_a_at
11751661_x_at
16746878
16746904
205854_PM_at
205854_at
221964_PM_at
221964_at
31942_at
31943_g_at
31944_at
3401200
3401219
3401220
3401228
3401230
3401231
3401233
3401235
3401237
3401240
3401242
3401244
3401245
3401246
3401247
3401248
3401249
3401250
3401251
3401252
3401253
3401254
45162_at
7289
74737_at
74739_g_at
7953135
82197_at
A_33_P3405789
GO:0001664
GO:0001841
GO:0001843
GO:0005515
GO:0005546
GO:0005576
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005856
GO:0005886
GO:0005929
GO:0005930
GO:0006351
GO:0006355
GO:0007186
GO:0007224
GO:0007420
GO:0008277
GO:0008289
GO:0008589
GO:0009952
GO:0016020
GO:0019899
GO:0021904
GO:0021915
GO:0021953
GO:0023052
GO:0030154
GO:0031076
GO:0035091
GO:0042733
GO:0042995
GO:0043226
GO:0044877
GO:0045879
GO:0048702
GO:0048856
GO:0060173
GO:0060348
GO:0060434
GO:0060831
GO:0061512
GO:0061548
GO:0097546
GO:0097731
GO:0120160
HMNXSV003051018
Hs.169084.0.S2_3p_at
Hs.39706.0.A1_3p_at
ILMN_1719199
TC12003230.hg
Participates
as an input of
The IFT-A complex recruits TULP3 (Homo sapiens)
as a component of
IFT-A complex:TULP3 [cilium] (Homo sapiens)
Inferred To
Tulp3 [cilium]
(Mus musculus)
Tulp3 [cilium]
(Rattus norvegicus)
si:dkey-220f10.4 [cilium]
(Danio rerio)
tub-1 [cilium]
(Caenorhabditis elegans)
TULP3 [cilium]
(Bos taurus)
TULP3 [cilium]
(Canis familiaris)
TULP3 [cilium]
(Gallus gallus)
TULP3 [cilium]
(Plasmodium falciparum)
TULP3 [cilium]
(Sus scrofa)
ktub [cilium]
(Drosophila melanogaster)
tulp3 [cilium]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001153880.1
,
NP_003315.2
OpenTargets
ENSG00000078246
GeneCards
O75386
HPA
ENSG00000078246-TULP3
Ensembl
ENSG00000078246
,
ENST00000540184
,
ENSP00000410051
,
ENSP00000380321
,
ENST00000397132
,
ENSP00000444110
,
ENST00000448120
PRO
O75386
Pharos - Targets
O75386
PDB
8FH3
Interactors (37)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6NXT1 ANR54
0.905
10
UniProt:Q96RY7 IFT140
2
IFT140 [cilium]
(R-HSA-5610382)
IFT140 [ciliary tip]
(R-HSA-5625345)
0.823
9
UniProt:Q8NEZ3 WDR19
2
WDR19 [cilium]
(R-HSA-5610446)
WDR19 [ciliary tip]
(R-HSA-5625347)
0.823
10
UniProt:Q9HBG6 IFT122
2
IFT122 [ciliary tip]
(R-HSA-5625346)
IFT122 [cilium]
(R-HSA-5610379)
0.823
7
UniProt:Q7Z4L5 TTC21B
2
TTC21B [ciliary tip]
(R-HSA-5625349)
TTC21B [cilium]
(R-HSA-5610430)
0.789
8
UniProt:P43360 MAGA6
0.781
7
UniProt:Q9BYV9 BACH2
0.742
5
UniProt:Q96FT9 IFT43
2
IFT43 [cilium]
(R-HSA-5617619)
IFT43 [ciliary tip]
(R-HSA-5625348)
0.725
5
UniProt:Q01167 FOXK2
1
FOXK2 [nucleoplasm]
(R-HSA-5689655)
0.725
4
UniProt:O43586 PSTPIP1
1
PSTPIP1 [cytosol]
(R-HSA-879220)
0.718
6
UniProt:Q9P2L0 WDR35
2
WDR35 [ciliary tip]
(R-HSA-5625351)
WDR35 [cilium]
(R-HSA-5610448)
0.638
4
UniProt:O75031 HSF2B
0.556
3
IntAct:EBI-10173330 386677
0.556
3
UniProt:Q9HAT0 ROPN1
1
ROPN1 [cytosol]
(R-HSA-5667048)
0.556
3
UniProt:P60370 KRTAP10-5
1
KRTAP10-5 [cytosol]
(R-HSA-6810260)
0.556
3
UniProt:P60409 KRTAP10-7
1
KRTAP10-7 [cytosol]
(R-HSA-6810279)
0.556
3
UniProt:Q96EB6 SIRT1
1
SIRT1 [nucleoplasm]
(R-HSA-427531)
0.527
2
UniProt:P11274 BCR
4
BCR(1-584)-p-FGFR1(429-822) fusion [cytosol]
(R-HSA-1838979)
p-Y177-BCR(1-584)-p-FGFR1(429-822) fusion [cytosol]
(R-HSA-1839041)
BCR(1-584)-FGFR1(429-822) fusion [cytosol]
(R-HSA-1604524)
BCR [cytosol]
(R-HSA-195200)
0.527
2
UniProt:Q8WVZ9 KBTBD7
1
KBTBD7 [cytosol]
(R-HSA-5658415)
0.527
2
UniProt:P27361 MAPK3
6
MAPK3 [endoplasmic reticulum lumen]
(R-HSA-9636295)
p-T202-MAPK3 [cytosol]
(R-HSA-9635775)
MAPK3 [nucleoplasm]
(R-HSA-73724)
MAPK3 [cytosol]
(R-HSA-59284)
p-T202,Y204-MAPK3 [cytosol]
(R-HSA-109842)
p-T202,Y204-MAPK3 [nucleoplasm]
(R-HSA-112359)
0.527
2
UniProt:P36915 GNL1
0.527
2
UniProt:P56539 CAV3
1
CAV3 [plasma membrane]
(R-HSA-1368135)
0.527
2
UniProt:Q8TBX8 PIP4K2C
2
PIP4K2C [nucleoplasm]
(R-HSA-6811499)
PIP4K2C [cytosol]
(R-HSA-1604638)
0.527
2
UniProt:Q9NXF7 DCAF16
1
DCAF16 [nucleoplasm]
(R-HSA-8955193)
0.527
2
UniProt:Q9P2K6 KLHL42
1
KLHL42 [cytosol]
(R-HSA-8863204)
0.527
2
UniProt:P85037 FOXK1
1
FOXK1 [nucleoplasm]
(R-HSA-5689673)
0.527
2
UniProt:Q9BZG8 DPH1
1
DPH1 [cytosol]
(R-HSA-5358384)
0.527
2
UniProt:O95376 ARIH2
1
ARIH2 [cytosol]
(R-HSA-975987)
0.527
2
UniProt:Q9NS91 RAD18
1
RAD18 [nucleoplasm]
(R-HSA-5643731)
0.527
2
UniProt:Q9H9L4 KANSL2
1
KANSL2 [nucleoplasm]
(R-HSA-3321796)
0.527
2
UniProt:Q96S90 LYSM1
0.527
2
UniProt:Q93009 USP7
2
USP7 [cytosol]
(R-HSA-8853511)
USP7 [nucleoplasm]
(R-HSA-3215278)
0.527
2
UniProt:Q9Y4X5 ARIH1
1
ARIH1 [cytosol]
(R-HSA-1678825)
0.527
2
UniProt:O95453 PARN
1
PARN [cytosol]
(R-HSA-430009)
0.527
2
UniProt:O95749 GGPS1
1
GGPS1 [cytosol]
(R-HSA-191415)
0.527
2
UniProt:Q96HC4 PDLIM5
1
PDLIM5 [cytosol]
(R-HSA-6794246)
0.527
2
UniProt:P12520 VPR
0.499
2
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