Organic anion transport

Stable Identifier
R-HSA-561048
Type
Pathway
Species
Homo sapiens
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Organic anion transporters (OATs) mediate the renal absorption and excretion of a broad range of endogenous substrates and anionic drugs such as diuretics and NSAIDs. Five members belong to these polyspecific transporters (OAT1-4 and URAT1) and are predominantly expressed in the kidney (Koepsell H and Endou H, 2004; Rizwan AN and Burckhardt G, 2007; Ahn SY and Bhatnagar V, 2008).

Literature References
PubMed ID Title Journal Year
17245646 Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles

Rizwan, AN, Burckhardt, G

Pharm Res 2007
18695391 Update on the molecular physiology of organic anion transporters

Ahn, SY, Bhatnagar, V

Curr Opin Nephrol Hypertens 2008
12883891 The SLC22 drug transporter family

Koepsell, H, Endou, H

Pflugers Arch 2004
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