Reactome: A Curated Pathway Database

GSK3 phosphorylates p-GLI3

Stable Identifier
R-HSA-5610732
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

GSK3-mediated phosphorylation of GLI3 is primed by earlier phosphorylations by PKA and CK1 and is required for the subsequent recruitment of beta-TrCP (Tempe et al, 2006; Wang and Li, 2006).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein serine/threonine kinase activity of GSK3B [cytosol] GSK3B [cytosol] protein serine/threonine kinase activity (0004674)
Orthologous Events