GSK3 phosphorylates p-GLI3

Stable Identifier
R-HSA-5610732
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

GSK3-mediated phosphorylation of GLI3 is primed by earlier phosphorylations by PKA and CK1 and is required for the subsequent recruitment of beta-TrCP (Tempe et al, 2006; Wang and Li, 2006).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of GSK3B [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed