Reactome | SLC22A18 [plasma membrane]

SLC22A18 [plasma membrane]

Stable Identifier

R-HSA-561110

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

ORCTL2, Organic cation transporter-like protein 2, Solute carrier family 22 member 18, S22AI_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P20036 HLA-DPA1

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External Reference Information

External Reference

UniProt:Q96BI1 SLC22A18

Gene Names

SLC22A18, BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5

Chain

chain:1-424

Reference Genes

BioGPS Gene:5002 SLC22A18

COSMIC (genes):SLC22A18 SLC22A18

CTD Gene:5002 SLC22A18

dbSNP Gene:5002 SLC22A18

ENSEMBL:ENSG00000110628 SLC22A18

ENSEMBL_homo_sapiens_GENE:ENSG00000110628.16 SLC22A18

HGNC:10964 SLC22A18

KEGG Gene (Homo sapiens):5002 SLC22A18

Monarch:5002 SLC22A18

NCBI Gene:5002 SLC22A18

OMIM:602631 SLC22A18

UCSC:Q96BI1 SLC22A18

Reference Transcript

Other Identifiers

11756459_a_at

16720959

204981_PM_at

204981_at

3317521

3317522

3317523

3317524

3317525

3317527

3317528

3317529

3317530

3317531

3317532

3317533

3317538

3317540

3317542

3317546

3317547

3317548

3317549

39992_at

5002

7937852

A_14_P200283

A_23_P127868

A_23_P139260

GE54233

GO:0005215

GO:0005515

GO:0005634

GO:0005635

GO:0005737

GO:0005886

GO:0006811

GO:0015293

GO:0015695

GO:0016020

GO:0016324

GO:0022857

GO:0031625

GO:0042908

GO:0042910

GO:0043226

GO:0055085

GO:0098754

GO:1990961

HMNXSV003035989

ILMN_1724902

ILMN_2382505

PH_hs_0003513

TC11000069.hg

g4505526_3p_at

Other forms of this molecule

SLC22A18 S233F [plasma membrane]

SLC22A18 R286H [plasma membrane]

Inferred To

Slc22a18 [plasma membrane] (Mus musculus)

Slc22a18 [plasma membrane] (Rattus norvegicus)

slc22a18 [plasma membrane] (Danio rerio)

slc22a18 [plasma membrane] (Xenopus tropicalis)

SLC22A18 [plasma membrane] (Bos taurus)

SLC22A18 [plasma membrane] (Caenorhabditis elegans)

SLC22A18 [plasma membrane] (Canis familiaris)

SLC22A18 [plasma membrane] (Gallus gallus)

SLC22A18 [plasma membrane] (Plasmodium falciparum)

SLC22A18 [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_001302430.1, NP_002546.3, NP_001302431.1, NP_899056.2

Guide to Pharmacology - Targets

1036

OpenTargets

ENSG00000110628

GeneCards

Q96BI1

HPA

ENSG00000110628-SLC22A18

Ensembl

ENST00000380574, ENST00000649076, ENSP00000307859, ENSP00000369948, ENST00000347936, ENSG00000110628, ENSP00000497561

PRO

Q96BI1

Pharos - Targets

Q96BI1

Orphanet

23355

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y320 TMX2			0.556	3
UniProt:Q8NBQ5 HSD17B11	1	HSD17B11 [cytosol] (R-HSA-5693370)	0.556	3
UniProt:Q99801 NKX31			0.556	3
UniProt:Q96MV1 TLCD4			0.556	3
UniProt:Q96G30 MRAP2			0.527	2
UniProt:P20036 HLA-DPA1	9	HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (R-HSA-2130667) HLA class II histocompatibility antigen, DP alpha chain precursor [ER to Golgi transport vesicle membrane] (R-HSA-2130739) HLA class II histocompatibility antigen, DP alpha chain precursor [Golgi membrane] (R-HSA-2214387) HLA class II histocompatibility antigen, DP alpha chain precursor [trans-Golgi network membrane] (R-HSA-2130337) HLA class II histocompatibility antigen, DP alpha chain precursor [transport vesicle membrane] (R-HSA-2130648) HLA class II histocompatibility antigen, DP alpha chain precursor [clathrin-coated endocytic vesicle membrane] (R-HSA-2130485) HLA class II histocompatibility antigen, DP alpha chain precursor [endocytic vesicle membrane] (R-HSA-2130435) HLA class II histocompatibility antigen, DP alpha chain precursor [lysosomal membrane] (R-HSA-2130639) HLA class II histocompatibility antigen, DP alpha chain precursor [plasma membrane] (R-HSA-197586)	0.527	2
UniProt:Q8TDQ0 HAVCR2	1	HAVCR2 [plasma membrane] (R-HSA-5340408)	0.527	2
UniProt:P02724 GYPA	1	GYPA [plasma membrane] (R-HSA-8867204)	0.527	2
UniProt:Q9ULX7 CA14	1	CA14 [plasma membrane] (R-HSA-1237018)	0.527	3

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