Reactome | IFT81 [cilium]

IFT81 [cilium]

Stable Identifier

R-HSA-5617769

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cilium

Synonyms

CDV1, IFT B

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WYA0 IFT81

Gene Names

IFT81, CDV1

Chain

initiator methionine:, chain:2-676

Reference Genes

BioGPS Gene:28981 IFT81

COSMIC (genes):IFT81 IFT81

CTD Gene:28981 IFT81

dbSNP Gene:28981 IFT81

ENSEMBL:ENSG00000122970 IFT81

HGNC:14313 IFT81

Monarch:28981 IFT81

NCBI Gene:28981 IFT81

OMIM:605489 IFT81

UCSC:Q8WYA0 IFT81

Reference Transcript

Other Identifiers

11735455_at

11735715_a_at

11759160_at

16756895

219372_PM_at

219372_at

223736_PM_at

223736_at

28981

3431428

3431429

3431430

3431431

3431433

3431434

3431435

3431436

3431437

3431438

3431439

3431440

3431441

3431442

3431443

3431444

3431445

3431446

3431447

3431448

3431449

3431450

3431452

3431453

3431454

3431455

3431458

3431459

3431460

3431461

3431462

59268_at

7958620

A_14_P106806

A_14_P109610

A_14_P129796

A_23_P48130

A_24_P164123

A_33_P3234984

A_33_P3234989

GE55642

GO:0005515

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005929

GO:0007018

GO:0007283

GO:0008092

GO:0008589

GO:0015631

GO:0022414

GO:0030030

GO:0030154

GO:0030992

GO:0031514

GO:0035720

GO:0035735

GO:0036064

GO:0042073

GO:0043226

GO:0044782

GO:0060271

GO:0097225

GO:0097228

GO:0097542

GO:0120316

HMNXSV003024644

HMNXSV003038825

ILMN_1655504

ILMN_1743753

ILMN_2254123

PH_hs_0016300

TC12000855.hg

g13528671_3p_at

g7661539_3p_at

g7661539_3p_x_at

Participates

as an input of

Assembly of IFT B complex (Homo sapiens)

as a component of

IFT B* [cilium] (Homo sapiens)

Other forms of this molecule

IFT81 [ciliary tip]

Inferred To

IFT81 [cilium] (Bos taurus)

IFT81 [cilium] (Canis familiaris)

IFT81 [cilium] (Gallus gallus)

IFT81 [cilium] (Sus scrofa)

ift-81 [cilium] (Caenorhabditis elegans)

Ift81 [cilium] (Mus musculus)

Ift81 [cilium] (Rattus norvegicus)

Cross References

OpenTargets

ENSG00000122970

ENSEMBL

ENST00000361948, ENST00000242591, ENST00000552912, ENSP00000242591, ENSP00000449718, ENSP00000355372

HPA

ENSG00000122970-IFT81

PRO

Q8WYA0

Pharos - Targets

Q8WYA0

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96LB3 IFT74	2	IFT74 [ciliary tip] (R-HSA-5625364) IFT74 [cilium] (R-HSA-5617616)	0.725	6
UniProt:Q8N4P2 IFT70B	2	TTC30B [ciliary tip] (R-HSA-5637970) TTC30B [cilium] (R-HSA-5637971)	0.725	5
UniProt:Q86WT1 IFT70A	2	TTC30A [ciliary tip] (R-HSA-5637966) TTC30A [cilium] (R-HSA-5637968)	0.725	5
UniProt:Q9BW83 IFT27	2	IFT27 [ciliary tip] (R-HSA-5625357) IFT27 [cilium] (R-HSA-5617621)	0.69	5
UniProt:Q9Y547 HSPB11	2	HSPB11 [ciliary tip] (R-HSA-5625342) HSPB11 [cilium] (R-HSA-5617628)	0.69	6
UniProt:Q13099 IFT88	8	PolyUb-Misfolded IFT88 [lysosomal lumen] (R-HSA-9660026) PolyUb-Misfolded IFT88 [cytosol] (R-HSA-9641125) Ub-Misfolded IFT88 [cytosol] (R-HSA-9641114) Misfolded IFT88 [cytosol] (R-HSA-9640115) Misfolded IFT88 [cilium] (R-HSA-9640106) IFT88 [cilium] (R-HSA-5610385) PolyUb-Misfolded IFT88 [late endosome lumen] (R-HSA-9660031) IFT88 [ciliary tip] (R-HSA-5625371)	0.643	6
UniProt:Q9H7X7 IFT22	2	RABL5 [cilium] (R-HSA-5617605) RABL5 [ciliary tip] (R-HSA-5625388)	0.638	4
UniProt:Q9NQC8 IFT46	2	IFT46 [ciliary tip] (R-HSA-5625359) IFT46 [cilium] (R-HSA-5617617)	0.638	4
UniProt:Q9UG01 IFT172	2	IFT172 [ciliary tip] (R-HSA-5625353) IFT172 [cilium] (R-HSA-5610383)	0.592	4
UniProt:Q15154 PCM1	1	PCM1 [cytosol] (R-HSA-380308)	0.569	3
UniProt:Q9NWB7 IFT57	2	IFT57 [cilium] (R-HSA-5610389) IFT57 [ciliary tip] (R-HSA-5625363)	0.527	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.527	2
UniProt:P05120 SERPINB2	2	SERPINB2 [plasma membrane] (R-HSA-159004) SERPINB2 [extracellular region] (R-HSA-158997)	0.527	2
UniProt:P78395 PRAME			0.527	2
UniProt:Q8TCX5 RHPN1	1	RHPN1 [cytosol] (R-HSA-5667017)	0.527	2
UniProt:O14777 NDC80	1	NDC80 [cytosol] (R-HSA-375314)	0.527	2
UniProt:Q96JJ6 JPH4			0.527	2
UniProt:P36941 LTBR	1	LTBR [plasma membrane] (R-HSA-5668750)	0.527	2
UniProt:A5D8V7 ODAD3			0.527	2
UniProt:A0AVF1 TTC26	2	TTC26 [ciliary tip] (R-HSA-5637962) TTC26 [cilium] (R-HSA-5637963)	0.508	2
UniProt:Q9P2H3 IFT80	2	IFT80 [ciliary tip] (R-HSA-5625367) IFT80 [cilium] (R-HSA-5617613)	0.508	3
UniProt:Q9Y366 IFT52	2	IFT52 [ciliary tip] (R-HSA-5625360) IFT52 [cilium] (R-HSA-5610387)	0.508	2

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