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ARL13B [cilium]
Stable Identifier
R-HSA-5618181
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cilium
Locations in the PathwayBrowser for interactor UniProt:Q8N6G5
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Cargo trafficking to the periciliary membrane (Homo sapiens)
ARL13B-mediated ciliary trafficking of INPP5E (Homo sapiens)
ARL13B binds INPP5E (Homo sapiens)
ARL13B [cilium] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q3SXY8 ARL13B
Gene Names
ARL13B, ARL2L1
Chain
chain:1-428
Reference Genes
BioGPS Gene:200894 ARL13B
COSMIC (genes):ARL13B ARL13B
CTD Gene:200894 ARL13B
dbSNP Gene:200894 ARL13B
ENSEMBL:ENSG00000169379 ARL13B
ENSEMBL_homo_sapiens_GENE:ENSG00000169379.17 ARL13B
HGNC:25419 ARL13B
KEGG Gene (Homo sapiens):200894 ARL13B
Monarch:200894 ARL13B
NCBI Gene:200894 ARL13B
OMIM:608922 ARL13B
UCSC:Q3SXY8 ARL13B
Reference Transcript
RefSeq:NM_182896.2 ARL13B
RefSeq:NM_001174151.1 ARL13B
RefSeq:NM_144996.3 ARL13B
RefSeq:XM_017005853.1 ARL13B
RefSeq:NM_001174150.1 ARL13B
Other Identifiers
11727774_a_at
11745327_a_at
11748459_a_at
16942991
200894
228201_PM_at
228201_at
2632454
2632455
2632456
2632459
2632462
2632467
2632468
2632469
2632470
2632471
2632476
2632478
2632480
2632481
2632482
2632483
2632484
2632488
48263_at
79922_at
8081115
A_14_P200100
A_23_P10081
A_24_P328668
A_24_P465576
GE555014
GE88314
GO:0000166
GO:0001947
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005829
GO:0005856
GO:0005886
GO:0005929
GO:0005930
GO:0007224
GO:0007368
GO:0009953
GO:0016020
GO:0016787
GO:0021532
GO:0021830
GO:0021943
GO:0023052
GO:0030154
GO:0031514
GO:0042995
GO:0043226
GO:0044782
GO:0048856
GO:0048870
GO:0060170
GO:0060271
GO:0070986
GO:0097500
GO:0097730
GO:1905515
HMNXSV003028902
Hs.85992.0.A1_3p_at
ILMN_2403047
PH_hs_0024119
TC03000474.hg
TC03002422.hg
Participates
as an input of
ARL13B binds INPP5E (Homo sapiens)
as a component of
ARL13B:INPP5E [cilium] (Homo sapiens)
ARL13B:INPP5E:PDE6D [cilium] (Homo sapiens)
as a member of
Cilia proteins [cilium] (Homo sapiens)
Other forms of this molecule
PolyUb-Misfolded ARL13B [lysosomal lumen]
PolyUb-Misfolded ARL13B [cytosol]
Ub-Misfolded ARL13B [cytosol]
Misfolded ARL13B [cytosol]
Misfolded ARL13B [cilium]
PolyUb-Misfolded ARL13B [late endosome lumen]
ARL13B [plasma membrane]
Inferred To
Arl13b [cilium]
(Rattus norvegicus)
ARL13B [cilium]
(Bos taurus)
ARL13B [cilium]
(Canis familiaris)
ARL13B [cilium]
(Gallus gallus)
ARL13B [cilium]
(Mus musculus)
ARL13B [cilium]
(Sus scrofa)
Cross References
RefSeq
NP_001167621.1
,
NP_659433.2
,
NP_001167622.1
,
XP_016861342.1
,
NP_878899.1
OpenTargets
ENSG00000169379
GeneCards
Q3SXY8
HPA
ENSG00000169379-ARL13B
Ensembl
ENST00000394222
,
ENST00000471138
,
ENSP00000445145
,
ENST00000303097
,
ENSG00000169379
,
ENSP00000377769
,
ENSP00000306225
,
ENST00000535334
,
ENSP00000420780
PRO
Q3SXY8
Pharos - Targets
Q3SXY8
Orphanet
18076
Interactors (129)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63252 KCNJ2
1
KCNJ2 [plasma membrane]
(R-HSA-975378)
0.659
4
UniProt:Q9NZ01 TECR
1
TECR [endoplasmic reticulum membrane]
(R-HSA-548663)
0.556
3
UniProt:A5D903 A5D903
0.556
3
UniProt:Q9Y6I9 TEX264
2
TEX264 [extracellular region]
(R-HSA-8863002)
TEX264 [platelet alpha granule lumen]
(R-HSA-8863000)
0.556
3
UniProt:Q13021 MALL
0.556
3
UniProt:Q96MV8 ZDH15
0.556
3
UniProt:Q8WVX3-2 C4ORF3
0.556
3
UniProt:Q15836 VAMP3
6
VAMP3 [recycling endosome membrane]
(R-HSA-2029063)
VAMP3 [phagocytic vesicle membrane]
(R-HSA-2029013)
VAMP3 [plasma membrane]
(R-HSA-8867599)
VAMP3 [trans-Golgi network membrane]
(R-HSA-6814624)
VAMP3 [transport vesicle]
(R-HSA-6814625)
VAMP3 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869130)
0.556
3
UniProt:A2RU14 TM218
0.556
3
UniProt:Q8N138 ORMDL3
4
ORMDL3 [secretory granule membrane]
(R-HSA-6800882)
ORMDL3 [plasma membrane]
(R-HSA-6806293)
ORMDL3 [specific granule membrane]
(R-HSA-6799643)
ORMDL3 [endoplasmic reticulum membrane]
(R-HSA-8865589)
0.556
3
UniProt:O14735 CDIPT
1
CDIPT [endoplasmic reticulum membrane]
(R-HSA-1498749)
0.556
3
UniProt:Q9H0Q3 FXYD6
1
FXYD6 [plasma membrane]
(R-HSA-2752104)
0.556
3
UniProt:Q8N661 TMEM86B
1
TMEM86B [endoplasmic reticulum membrane]
(R-HSA-8874443)
0.556
3
IntAct:EBI-23624354 CCSB ORF ID
0.556
3
UniProt:Q9H2S6-2 TNMD
0.556
3
UniProt:P29033 GJB2
3
GJB2 [plasma membrane]
(R-HSA-53211)
GJB2 [endoplasmic reticulum membrane]
(R-HSA-1629779)
GJB2 [endoplasmic reticulum-Golgi intermediate compartment]
(R-HSA-190614)
0.556
3
UniProt:P29034 S10A2
0.556
3
UniProt:Q0VAQ4 SMAGP
0.556
3
UniProt:Q6UXB4 CLEC4G
1
CLEC4G [plasma membrane]
(R-HSA-1472852)
0.556
3
UniProt:O95214 LERL1
0.556
3
UniProt:Q9NTN9-2 SEMA4G
0.556
3
UniProt:Q96F15 GIMA5
0.556
3
UniProt:P26678 PLN
2
p-S16-PLN [sarcoplasmic reticulum membrane]
(R-HSA-5578813)
PLN [sarcoplasmic reticulum membrane]
(R-HSA-5490319)
0.556
3
UniProt:Q8N5M9 JAGN1
0.556
3
UniProt:Q96MX0 CKLF3
0.556
3
UniProt:O14569 C56D2
0.556
3
UniProt:Q8IX05 CD302
0.556
3
UniProt:Q9NSC5 HOMER3
1
HOMER3 [cytosol]
(R-HSA-6794236)
0.556
3
UniProt:Q9NVV5-2 AIG1
0.556
3
UniProt:Q96FZ5 CKLF7
0.556
3
UniProt:Q59EV6 Q59EV6
0.556
3
UniProt:Q8IXM6 NRM
0.556
3
UniProt:Q8NHW4 CCL4L1
1
CCL4L1 [extracellular region]
(R-HSA-8865389)
0.556
3
UniProt:O15400 STX7
0.556
3
UniProt:O14798 TNFRSF10C
1
TNFRSF10C [plasma membrane]
(R-HSA-5628831)
0.556
3
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.556
3
UniProt:Q13113 PDZ1I
0.556
3
UniProt:P09601 HMOX1
4
HMOX1 [nucleoplasm]
(R-HSA-9708567)
HMOX1 [mitochondrial outer membrane]
(R-HSA-9708524)
HMOX1 [endoplasmic reticulum membrane]
(R-HSA-189395)
HMOX1 [cytosol]
(R-HSA-9609901)
0.556
3
UniProt:P78383 S35B1
0.556
3
UniProt:Q5BJF2 SGMR2
0.556
3
UniProt:P78382 SLC35A1
2
SLC35A1 [Golgi membrane]
(R-HSA-727812)
SLC35A1 V93Cfs*17 [Golgi membrane]
(R-HSA-5651957)
0.556
3
UniProt:P09466 PAEP
0.556
3
UniProt:Q96PS8 AQP10
1
AQP10 [plasma membrane]
(R-HSA-431709)
0.556
3
UniProt:O95393 BMP10
2
BMP10(22-424) [extracellular region]
(R-HSA-2396409)
BMP10 [extracellular region]
(R-HSA-8858374)
0.556
3
UniProt:Q5VZY2 PLPP4
1
PPAPDC1A [plasma membrane]
(R-HSA-2029082)
0.556
3
UniProt:P02786 TFRC
5
TFRC(1-760) [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869124)
TFRC(1-760) [Golgi membrane]
(R-HSA-434330)
TFRC(1-760) [cytoplasmic vesicle membrane]
(R-HSA-434196)
TFRC(1-760) [endosome membrane]
(R-HSA-8961829)
TFRC(1-760) [plasma membrane]
(R-HSA-917983)
0.556
3
UniProt:Q8NHY0 B4GALNT2
1
B4GALNT2 [Golgi membrane]
(R-HSA-8855939)
0.556
3
UniProt:Q96IV6 FXDC2
0.556
3
UniProt:Q5BJH2-2 TMEM128
0.556
3
UniProt:P0DN84 DWORF
0.556
3
UniProt:Q71RG4 TMUB2
0.556
3
UniProt:Q9BSE2 TMM79
0.556
3
UniProt:O60883 GPR37L1
1
GPR37L1 [plasma membrane]
(R-HSA-5336178)
0.556
3
UniProt:Q8NBD8 T229B
0.556
3
UniProt:Q86W74-2 ANKRD46
0.556
3
UniProt:Q15546 PAQRB
0.556
3
UniProt:Q9NZG7 NINJ2
0.556
3
IntAct:EBI-22331701 CCSB ORF ID
0.556
3
UniProt:P23763-3 VAMP1
0.556
3
UniProt:Q9NWW5 CLN6
0.556
3
UniProt:Q6PI78 TMM65
0.556
3
UniProt:Q9UBY5 LPAR3
1
LPAR3 [plasma membrane]
(R-HSA-419379)
0.556
3
UniProt:P30519 HMOX2
3
HMOX2 [plasma membrane]
(R-HSA-6799676)
HMOX2 [specific granule membrane]
(R-HSA-6799628)
HMOX2 [endoplasmic reticulum membrane]
(R-HSA-189391)
0.556
3
UniProt:O14653 GOSR2
4
GOSR2 [Golgi membrane]
(R-HSA-6807755)
GOSR2 [endoplasmic reticulum membrane]
(R-HSA-5689451)
GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-535472)
GOSR2 [ER to Golgi transport vesicle membrane]
(R-HSA-5689800)
0.556
3
UniProt:Q969K7 TMM54
0.556
3
UniProt:O75355-2 ENTPD3
0.556
3
UniProt:Q5TGU0 TSPO2
0.556
3
UniProt:A5PKU2 A5PKU2
0.556
3
UniProt:Q9BTD3 TM121
0.556
3
UniProt:Q8WWP7 GIMA1
0.556
3
UniProt:Q8WZ59 TM190
0.556
3
UniProt:Q9UHJ9-5 PGAP2
0.556
3
UniProt:Q9BXN2-6 CLEC7A
0.556
3
UniProt:Q96EC8 YIPF6
2
YIPF6 [Golgi membrane]
(R-HSA-434346)
YIPF6 [cytoplasmic vesicle membrane]
(R-HSA-434199)
0.556
3
UniProt:Q6PL45-2 BRICD5
0.556
3
UniProt:Q9NTJ5 SACM1L
2
SACM1L [endoplasmic reticulum membrane]
(R-HSA-1604637)
SACM1L [Golgi membrane]
(R-HSA-1806242)
0.556
3
UniProt:Q9BTV4 TMM43
0.556
3
UniProt:O75425 MSPD3
0.556
3
UniProt:Q6UX27-3 VSTM1
0.556
3
UniProt:O14493 CLDN4
2
CLDN4 [plasma membrane]
(R-HSA-419987)
CLDN4 [cell junction]
(R-HSA-421244)
0.556
3
UniProt:P54849 EMP1
0.556
3
UniProt:Q9NP94 SLC39A2
1
SLC39A2 [plasma membrane]
(R-HSA-442395)
0.556
3
UniProt:P56748 CLDN8
2
CLDN8 [plasma membrane]
(R-HSA-419968)
CLDN8 [cell junction]
(R-HSA-421243)
0.556
3
UniProt:Q96DR8 MUCL1
18
Core 8 (MUCL1) [Golgi lumen]
(R-HSA-1462256)
Core 2S (MUCL1) [Golgi lumen]
(R-HSA-6786344)
Core 5 (MUCL1) [Golgi lumen]
(R-HSA-1462337)
Core 4 (MUCL1) [Golgi lumen]
(R-HSA-1462139)
Core 3 (MUCL1) [Golgi lumen]
(R-HSA-1462268)
GalNAc-MUCL1 [plasma membrane]
(R-HSA-8858459)
Core 2 (MUCL1) [Golgi lumen]
(R-HSA-1462316)
Core 2a (MUCL1) [Golgi lumen]
(R-HSA-6784294)
GalNAc-MUCL1 [Golgi lumen]
(R-HSA-913643)
Sialyl Tn antigen (MUCL1) [Golgi lumen]
(R-HSA-1463594)
T-antigen (MUCL1) [Golgi lumen]
(R-HSA-1462357)
Sialyl-2,3 T-antigen (MUCL1) [Golgi lumen]
(R-HSA-1463467)
Sialyl T-antigen (MUCL1) [Golgi lumen]
(R-HSA-1463524)
Disialyl T-antigen (MUCL1) [Golgi lumen]
(R-HSA-1463480)
MUCL1 [Golgi lumen]
(R-HSA-913632)
Core 6 (MUCL1) [Golgi lumen]
(R-HSA-1462246)
extended Core 6 (MUCL1) [Golgi lumen]
(R-HSA-1967042)
Core 7 (MUCL1) [Golgi lumen]
(R-HSA-1462181)
0.556
3
UniProt:Q14318 FKBP8
2
PolyUb-FKBP8 [mitochondrial outer membrane]
(R-HSA-6783001)
FKBP8 [mitochondrial outer membrane]
(R-HSA-5696928)
0.556
3
UniProt:P19397 CD53
3
CD53 [specific granule membrane]
(R-HSA-6804793)
CD53 [plasma membrane]
(R-HSA-6804817)
CD53 [tertiary granule membrane]
(R-HSA-6804799)
0.556
3
UniProt:Q9UHE5 NAT8
1
NAT8 [endoplasmic reticulum membrane]
(R-HSA-5692986)
0.556
3
UniProt:Q16617 NKG7
0.556
3
UniProt:O14523 C2C2L
0.556
3
UniProt:Q969L2 MAL2
0.556
3
UniProt:Q16853 AOC3
1
AOC3 [plasma membrane]
(R-HSA-5696151)
0.556
3
UniProt:P13236 CCL4
1
CCL4(24-92) [extracellular region]
(R-HSA-443976)
0.556
3
UniProt:Q9P0B6 CC167
0.556
3
UniProt:Q01453 PMP22
1
PMP22 [plasma membrane]
(R-HSA-9615623)
0.556
3
UniProt:Q8N6G5 CSGALNACT2
1
CSGALNACT2 [Golgi membrane]
(R-HSA-1971506)
0.556
3
UniProt:P60201-2 PLP1
0.556
3
UniProt:P11215 ITGAM
3
ITGAM [specific granule membrane]
(R-HSA-6799647)
ITGAM [tertiary granule membrane]
(R-HSA-6800979)
ITGAM [plasma membrane]
(R-HSA-202757)
0.556
3
UniProt:Q8TBM7 TM254
0.556
3
UniProt:A6NDP7 MADL2
0.556
3
UniProt:Q9BXR6 CFHR5
1
CFHR5 [extracellular region]
(R-HSA-8851419)
0.556
3
UniProt:Q9BWH2 FUND2
0.556
3
UniProt:Q9UPZ6 THSD7A
3
THSD7A [endoplasmic reticulum lumen]
(R-HSA-5173009)
glc-fuc-THSD7A [endoplasmic reticulum lumen]
(R-HSA-5173197)
O-fuc-THSD7A [endoplasmic reticulum lumen]
(R-HSA-5173184)
0.556
3
UniProt:Q12983 BNIP3
0.556
3
UniProt:O60725 ICMT
1
ICMT [endoplasmic reticulum membrane]
(R-HSA-6788651)
0.556
3
UniProt:CXCL16 A0A6I8PIU0
0.556
3
UniProt:Q4VAQ0 Q4VAQ0
0.556
3
UniProt:Q9P0S9 TM14C
0.556
3
UniProt:Q96GM1 PLPPR2
1
LPPR2 [plasma membrane]
(R-HSA-6797629)
0.556
3
UniProt:Q9C0I4 THSD7B
3
THSD7B [endoplasmic reticulum lumen]
(R-HSA-5173101)
glc-fuc-THSD7B [endoplasmic reticulum lumen]
(R-HSA-5172957)
O-fuc-THSD7B [endoplasmic reticulum lumen]
(R-HSA-5173124)
0.556
3
UniProt:Q9BZW4 TM6S2
0.556
3
UniProt:Q9P0S3 ORMDL1
1
ORMDL1 [endoplasmic reticulum membrane]
(R-HSA-8865584)
0.556
3
UniProt:P43378 PTPN9
1
PTPN9 [nucleoplasm]
(R-HSA-9008907)
0.556
3
UniProt:P22732 SLC2A5
2
SLC2A5 [plasma membrane]
(R-HSA-189202)
SLC2A5 [specific granule membrane]
(R-HSA-6799571)
0.556
3
UniProt:Q9NVC3 S38A7
0.556
3
UniProt:P17152 TMEM11
1
TMEM11 [mitochondrial inner membrane]
(R-HSA-8949578)
0.556
3
UniProt:Q14656 TM187
0.556
3
UniProt:Q05329 GAD2
2
PXLP-K396-GAD2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-888582)
PXLP-K396-GAD2 [plasma membrane]
(R-HSA-936509)
0.556
3
UniProt:Q14508 WFDC2
1
WFDC2 [extracellular region]
(R-HSA-9830363)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:Q5QGT7 RTP2
2
RTP2 [endoplasmic reticulum membrane]
(R-HSA-9752982)
RTP2 [plasma membrane]
(R-HSA-8939446)
0.556
3
UniProt:Q92685 ALG3
5
ALG3 [endoplasmic reticulum membrane]
(R-HSA-449287)
ALG3 W71R [endoplasmic reticulum membrane]
(R-HSA-4720466)
ALG3 G118D [endoplasmic reticulum membrane]
(R-HSA-4720468)
ALG3 M157K [endoplasmic reticulum membrane]
(R-HSA-4720484)
ALG3 R171Q [endoplasmic reticulum membrane]
(R-HSA-4720470)
0.556
3
UniProt:P37268 FDFT1
1
FDFT1 [endoplasmic reticulum membrane]
(R-HSA-191369)
0.556
3
UniProt:P48509 CD151
2
CD151 [cytosol]
(R-HSA-446072)
CD151 [plasma membrane]
(R-HSA-913947)
0.556
3
UniProt:Q8WWT9 SLC13A3
1
SLC13A3 [plasma membrane]
(R-HSA-433095)
0.556
3
UniProt:Q96CM8 ACSF2
1
ACSF2 [mitochondrial matrix]
(R-HSA-5696005)
0.556
3
UniProt:O75379 VAMP4
4
VAMP4 [transport vesicle]
(R-HSA-6811023)
VAMP4 [trans-Golgi network membrane]
(R-HSA-6811021)
VAMP4 [plasma membrane]
(R-HSA-8864461)
VAMP4 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869133)
0.556
3
UniProt:P16150 SPN
1
SPN [plasma membrane]
(R-HSA-204438)
0.556
3
UniProt:Q96E93 KLRG1
1
KLRG1 [plasma membrane]
(R-HSA-198006)
0.556
3
UniProt:P63027 VAMP2
20
VAMP2 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869129)
VAMP2 [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-379363)
VAMP2 [plasma membrane]
(R-HSA-210516)
VAMP2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-917738)
VAMP2 [clathrin-sculpted glutamate transport vesicle membrane]
(R-HSA-210365)
VAMP2 [synaptic vesicle membrane]
(R-HSA-181517)
VAMP2(59-116) [synaptic vesicle membrane]
(R-HSA-5250891)
VAMP2(2-58) [cytosol]
(R-HSA-194815)
VAMP2(2-76) [cytosol]
(R-HSA-194802)
VAMP2(77-116) [synaptic vesicle membrane]
(R-HSA-5228355)
VAMP2(60-116) [synaptic vesicle membrane]
(R-HSA-5250615)
VAMP2(2-59) [cytosol]
(R-HSA-194797)
VAMP2(82-116) [synaptic vesicle membrane]
(R-HSA-5250961)
VAMP2(2-81) [cytosol]
(R-HSA-5250970)
VAMP2 [secretory granule membrane]
(R-HSA-376363)
VAMP2 [cytosol]
(R-HSA-9609882)
VAMP2 [endoplasmic reticulum membrane]
(R-HSA-9609886)
VAMP2 [cytoplasmic vesicle membrane]
(R-HSA-1449630)
VAMP2 [lysosomal membrane]
(R-HSA-432703)
VAMP2 [Golgi membrane]
(R-HSA-375425)
0.556
3
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