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UNC119B [cilium]
Stable Identifier
R-HSA-5618271
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cilium
Locations in the PathwayBrowser
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Cargo trafficking to the periciliary membrane (Homo sapiens)
Trafficking of myristoylated proteins to the cilium (Homo sapiens)
ARL3 hydrolyzes GTP (Homo sapiens)
RP2:ARL3:GDP:UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
RP2:ARL3:GTP:UNC119B(active) [cilium] (Homo sapiens)
ARL3:GTP:UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
ARL3:GTP binds the UNC119B complex (Homo sapiens)
ARL3:GTP:UNC119B:myristoylated ciliary cargo [cilium] (Homo sapiens)
UNC119B:myristoylated ciliary cargo [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
UNC119B:myristoylated ciliary cargo [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
Myristoylated NPHP3 translocates into the ciliary membrane (Homo sapiens)
ARL3:GTP:UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
ARL3:GTP:UNC119B:myristoylated ciliary cargo [cilium] (Homo sapiens)
UNC119B:myristoylated ciliary cargo [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
RP2 activates the GTPase activity of ARL3 (Homo sapiens)
RP2:ARL3:GTP:UNC119B [cilium] (Homo sapiens)
ARL3:GTP:UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
RP2:ARL3:GTP:UNC119B(active) [cilium] (Homo sapiens)
ARL3:GTP:UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
RP2 binds ARL3:GTP:UNC119B (Homo sapiens)
ARL3:GTP:UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
RP2:ARL3:GTP:UNC119B [cilium] (Homo sapiens)
ARL3:GTP:UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
RP2:ARL3:GDP:UNC119B dissociates (Homo sapiens)
RP2:ARL3:GDP:UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium (Homo sapiens)
UNC119B:myristoylated ciliary cargo [cilium] (Homo sapiens)
UNC119B [cilium] (Homo sapiens)
External Reference Information
External Reference
UniProt:A6NIH7 UNC119B
Gene Names
UNC119B
Chain
initiator methionine:, chain:2-251
Reference Genes
BioGPS Gene:84747 UNC119B
COSMIC (genes):UNC119B UNC119B
CTD Gene:84747 UNC119B
dbSNP Gene:84747 UNC119B
ENSEMBL:ENSG00000175970 UNC119B
ENSEMBL_homo_sapiens_GENE:ENSG00000175970.11 UNC119B
HGNC:16488 UNC119B
KEGG Gene (Homo sapiens):84747 UNC119B
Monarch:84747 UNC119B
NCBI Gene:84747 UNC119B
OMIM:620513 UNC119B
UCSC:A6NIH7 UNC119B
Reference Transcript
RefSeq:NM_001080533.2 UNC119B
Other Identifiers
11716484_at
11758424_s_at
16757979
202365_PM_at
202365_at
3434566
3434567
3434568
3434569
3434570
3434571
3434572
3434573
3434574
3434575
3434577
3434579
3434581
3434583
3434585
3434587
3434591
3434593
3434595
3434596
3434597
7959212
84747
A_14_P111975
A_23_P87827
A_33_P3274478
GE83471
GO:0005515
GO:0005829
GO:0005929
GO:0007399
GO:0008289
GO:0015031
GO:0030030
GO:0035869
GO:0042953
GO:0042995
GO:0043226
GO:0044782
GO:0048856
GO:0060271
HMNXSV003009232
HMNXSV003012813
ILMN_1660935
PH_hs_0007328
TC12000950.hg
g13435956_3p_at
Participates
as an output of
RP2:ARL3:GDP:UNC119B dissociates (Homo sapiens)
as a component of
RP2:ARL3:GDP:UNC119B [cilium] (Homo sapiens)
ARL3:GTP:UNC119B [cilium] (Homo sapiens)
UNC119B:myristoylated ciliary cargo [cilium] (Homo sapiens)
Other forms of this molecule
UNC119B [cytosol]
Inferred To
UNC119B [cilium]
(Bos taurus)
UNC119B [cilium]
(Caenorhabditis elegans)
UNC119B [cilium]
(Canis familiaris)
UNC119B [cilium]
(Danio rerio)
UNC119B [cilium]
(Drosophila melanogaster)
UNC119B [cilium]
(Gallus gallus)
UNC119B [cilium]
(Mus musculus)
Unc119b [cilium]
(Rattus norvegicus)
Cross References
RefSeq
NP_001074002.1
OpenTargets
ENSG00000175970
HPA
ENSG00000175970-UNC119B
GeneCards
A6NIH7
Ensembl
ENST00000344651
,
ENSG00000175970
,
ENSP00000344942
PRO
A6NIH7
Pharos - Targets
A6NIH7
PDB
7OK7
,
7OK6
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P36405 ARL3
1
ARL3 [cilium]
(R-HSA-5618182)
0.725
5
UniProt:Q7Z494 NPHP3
2
MyrG2-NPHP3 [cytosol]
(R-HSA-5624091)
MyrG2-NPHP3 [cilium]
(R-HSA-5618254)
0.59
3
UniProt:Q96QS6 PSKH2
0.527
3
UniProt:Q13432 U119A
0.527
3
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