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SCLT1 [cytosol]
Stable Identifier
R-HSA-5620935
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SAP1
Locations in the PathwayBrowser
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Anchoring of the basal body to the plasma membrane (Homo sapiens)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
CP110 and CEP97 dissociate from the centriole (Homo sapiens)
basal body [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
MARK4 binds ODF2 in the centriole (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
RAB3IP stimulates nucleotide exchange on RAB8A (Homo sapiens)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
Recruitment of transition zone proteins (Homo sapiens)
basal body [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
The distal appendage proteins recruit TTBK2 (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
SCLT1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96NL6 SCLT1
Gene Names
SCLT1, SAP1
Chain
initiator methionine:1, chain:2-688
Reference Genes
BioGPS Gene:132320 SCLT1
COSMIC (genes):SCLT1 SCLT1
CTD Gene:132320 SCLT1
dbSNP Gene:132320 SCLT1
ENSEMBL:ENSG00000151466 SCLT1
HGNC:26406 SCLT1
KEGG Gene (Homo sapiens):132320 SCLT1
Monarch:132320 SCLT1
NCBI Gene:132320 SCLT1
OMIM:611399 SCLT1
UCSC:Q96NL6 SCLT1
Reference Transcript
RefSeq:NM_144643.3 SCLT1
RefSeq:NM_001300898.1 SCLT1
RefSeq:NM_001300897.1 SCLT1
Other Identifiers
0000050091
11734520_a_at
11734521_x_at
11745685_a_at
11745686_x_at
11753361_a_at
11759959_s_at
132320
1569190_at
16979719
236487_at
2785288
2785289
2785293
2785294
2785296
2785298
2785299
2785300
2785303
2785304
2785306
2785308
2785311
2785316
2785320
2785321
2785322
2785334
2785335
2785336
2785337
2785345
2785346
2785347
2785348
2785349
2785350
2785351
47239_r_at
8102751
A_33_P3340404
GE79547
GO:0003674
GO:0005575
GO:0005622
GO:0005737
GO:0005813
GO:0005814
GO:0005815
GO:0005829
GO:0005856
GO:0005929
GO:0008022
GO:0008150
GO:0017080
GO:0021700
GO:0022607
GO:0030154
GO:0030276
GO:0032991
GO:0043226
GO:0045162
GO:0048856
GO:0060271
GO:0061024
GO:0071439
GO:0097539
GO:0097711
Hs.159865.0.A1_3p_at
Hs2.397168.1.S1_3p_at
ILMN_1797107
PH_hs_0017504
TC04001540.hg
Participant Of
hasComponent
basal body [cytosol]
Centrosome:C2CD3:distal appendage proteins [cytosol]
input
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole
Inferred To
Sclt1 [cytosol] (Mus musculus)
Sclt1 [cytosol] (Rattus norvegicus)
SCLT1 [cytosol] (Canis familiaris)
SCLT1 [cytosol] (Sus scrofa)
Ghost homologue of SCLT1 [cytosol] (Danio rerio)
Ghost homologue of SCLT1 [cytosol] (Gallus gallus)
mcm6.2 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
NP_001287827.1
,
NP_653244.2
,
NP_001287826.1
OpenTargets
ENSG00000151466
HPA
ENSG00000151466-SCLT1
GeneCards
Q96NL6
Ensembl
ENST00000511426
,
ENST00000439369
,
ENSP00000395292
,
ENSP00000420861
,
ENSP00000281142
,
ENST00000281142
,
ENSG00000151466
PRO
Q96NL6
Orphanet
24886
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95684 CEP43
3
FGFR1OP-p-FGFR1 fusion [cytosol]
(R-HSA-1838994)
FGFR1OP-FGFR1 fusion [cytosol]
(R-HSA-1604533)
FGFR1OP [cytosol]
(R-HSA-380309)
0.527
2
UniProt:Q2M2Z5 KIZ
0.462
3
UniProt:O60826 CCDC22
2
CCDC22 [cytosol]
(R-HSA-8955640)
CCDC22 [nucleoplasm]
(R-HSA-8955644)
0.462
3
UniProt:Q86V48 LUZP1
0.462
3
UniProt:Q02241 KIF23
3
p-S904,S905-KIF23 [nucleoplasm]
(R-HSA-156695)
KIF23 [nucleoplasm]
(R-HSA-156709)
KIF23 [cytosol]
(R-HSA-1015863)
0.462
2
UniProt:Q9NX08 COMMD8
2
COMMD8 [cytosol]
(R-HSA-8955107)
COMMD8 [nucleoplasm]
(R-HSA-8955102)
0.462
2
UniProt:Q86X83 COMMD2
2
COMMD2 [cytosol]
(R-HSA-8955112)
COMMD2 [nucleoplasm]
(R-HSA-8955099)
0.462
3
UniProt:Q96A65 EXOC4
2
EXOC4 [plasma membrane]
(R-HSA-264989)
EXOC4 [cytosol]
(R-HSA-5623381)
0.462
2
UniProt:Q9UHD2 TBK1
5
p-S172-TBK1 [cytosol]
(R-HSA-168379)
pS-172,K48polyUb-TBK1 [cytosol]
(R-HSA-3249397)
p-S172-TBK1 [cytosol]
(R-HSA-450290)
p-TBK1 [cytosol]
(R-HSA-9008705)
TBK1 [cytosol]
(R-HSA-166267)
0.462
2
UniProt:Q04837 SSBP1
1
SSBP1 [mitochondrial matrix]
(R-HSA-1592217)
0.462
2
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