Reactome | SCLT1 [cytosol]

SCLT1 [cytosol]

Stable Identifier

R-HSA-5620935

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

SAP1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96NL6 SCLT1

Gene Names

SCLT1, SAP1

Chain

initiator methionine:1, chain:2-688

Reference Genes

BioGPS Gene:132320 SCLT1

COSMIC (genes):SCLT1 SCLT1

CTD Gene:132320 SCLT1

dbSNP Gene:132320 SCLT1

ENSEMBL:ENSG00000151466 SCLT1

HGNC:26406 SCLT1

KEGG Gene (Homo sapiens):132320 SCLT1

Monarch:132320 SCLT1

NCBI Gene:132320 SCLT1

OMIM:611399 SCLT1

UCSC:Q96NL6 SCLT1

Reference Transcript

Other Identifiers

0000050091

11734520_a_at

11734521_x_at

11745685_a_at

11745686_x_at

11753361_a_at

11759959_s_at

132320

1569190_at

16979719

236487_at

2785288

2785289

2785293

2785294

2785296

2785298

2785299

2785300

2785303

2785304

2785306

2785308

2785311

2785316

2785320

2785321

2785322

2785334

2785335

2785336

2785337

2785345

2785346

2785347

2785348

2785349

2785350

2785351

47239_r_at

8102751

A_33_P3340404

GE79547

GO:0003674

GO:0005575

GO:0005622

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005829

GO:0005856

GO:0005929

GO:0008022

GO:0008150

GO:0017080

GO:0021700

GO:0022607

GO:0030154

GO:0030276

GO:0032991

GO:0043226

GO:0045162

GO:0048856

GO:0060271

GO:0061024

GO:0071439

GO:0097539

GO:0097711

Hs.159865.0.A1_3p_at

Hs2.397168.1.S1_3p_at

ILMN_1797107

PH_hs_0017504

TC04001540.hg

Participant Of

hasComponent

input

C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole

Inferred To

Sclt1 [cytosol] (Mus musculus)

Sclt1 [cytosol] (Rattus norvegicus)

SCLT1 [cytosol] (Canis familiaris)

SCLT1 [cytosol] (Sus scrofa)

Ghost homologue of SCLT1 [cytosol] (Danio rerio)

Ghost homologue of SCLT1 [cytosol] (Gallus gallus)

mcm6.2 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001287827.1, NP_653244.2, NP_001287826.1

OpenTargets

ENSG00000151466

HPA

ENSG00000151466-SCLT1

GeneCards

Q96NL6

Ensembl

ENST00000511426, ENST00000439369, ENSP00000395292, ENSP00000420861, ENSP00000281142, ENST00000281142, ENSG00000151466

PRO

Q96NL6

Orphanet

24886

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95684 CEP43	3	FGFR1OP-p-FGFR1 fusion [cytosol] (R-HSA-1838994) FGFR1OP-FGFR1 fusion [cytosol] (R-HSA-1604533) FGFR1OP [cytosol] (R-HSA-380309)	0.527	2
UniProt:Q2M2Z5 KIZ			0.462	3
UniProt:O60826 CCDC22	2	CCDC22 [cytosol] (R-HSA-8955640) CCDC22 [nucleoplasm] (R-HSA-8955644)	0.462	3
UniProt:Q86V48 LUZP1			0.462	3
UniProt:Q02241 KIF23	3	p-S904,S905-KIF23 [nucleoplasm] (R-HSA-156695) KIF23 [nucleoplasm] (R-HSA-156709) KIF23 [cytosol] (R-HSA-1015863)	0.462	2
UniProt:Q9NX08 COMMD8	2	COMMD8 [cytosol] (R-HSA-8955107) COMMD8 [nucleoplasm] (R-HSA-8955102)	0.462	2
UniProt:Q86X83 COMMD2	2	COMMD2 [cytosol] (R-HSA-8955112) COMMD2 [nucleoplasm] (R-HSA-8955099)	0.462	3
UniProt:Q96A65 EXOC4	2	EXOC4 [plasma membrane] (R-HSA-264989) EXOC4 [cytosol] (R-HSA-5623381)	0.462	2
UniProt:Q9UHD2 TBK1	5	p-S172-TBK1 [cytosol] (R-HSA-168379) pS-172,K48polyUb-TBK1 [cytosol] (R-HSA-3249397) p-S172-TBK1 [cytosol] (R-HSA-450290) p-TBK1 [cytosol] (R-HSA-9008705) TBK1 [cytosol] (R-HSA-166267)	0.462	2
UniProt:Q04837 SSBP1	1	SSBP1 [mitochondrial matrix] (R-HSA-1592217)	0.462	2