Reactome | RP2 [cilium]

RP2 [cilium]

Stable Identifier

R-HSA-5624052

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cilium

Synonyms

XRP2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75695 RP2

Gene Names

RP2

Chain

initiator methionine:, chain:2-350

Reference Genes

BioGPS Gene:6102 RP2

COSMIC (genes):RP2 RP2

CTD Gene:6102 RP2

dbSNP Gene:6102 RP2

ENSEMBL:ENSG00000102218 RP2

ENSEMBL_homo_sapiens_GENE:ENSG00000102218.6 RP2

HGNC:10274 RP2

KEGG Gene (Homo sapiens):6102 RP2

Monarch:6102 RP2

NCBI Gene:6102 RP2

OMIM:300757 RP2

UCSC:O75695 RP2

Reference Transcript

RefSeq:NM_006915.2 RP2

Other Identifiers

11724595_at

17102955

205191_PM_at

205191_at

3975870

3975871

3975875

3975876

3975877

3975879

3975880

3975881

39964_at

6102

8167006

A_23_P22433

A_24_P134568

GE55180

GO:0000166

GO:0000287

GO:0005096

GO:0005515

GO:0005525

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005794

GO:0005814

GO:0005815

GO:0005856

GO:0005886

GO:0005929

GO:0006457

GO:0006892

GO:0007601

GO:0015031

GO:0016020

GO:0016192

GO:0016604

GO:0031410

GO:0036064

GO:0042995

GO:0043226

GO:0044782

GO:0050877

GO:0051082

GO:0060271

GO:0070062

GO:0098772

GO:1990075

HMNXSV003035984

ILMN_1659255

PH_hs_0027642

TC0X000222.hg

g5902059_3p_at

Participates

as an output of

RP2:ARL3:GDP:UNC119B dissociates (Homo sapiens)

as an input of

RP2 binds ARL3:GTP:UNC119B (Homo sapiens)

as a component of

Inferred To

RP2 [cilium] (Bos taurus)

RP2 [cilium] (Caenorhabditis elegans)

RP2 [cilium] (Canis familiaris)

RP2 [cilium] (Danio rerio)

RP2 [cilium] (Gallus gallus)

RP2 [cilium] (Mus musculus)

Rp2 [cilium] (Rattus norvegicus)

Cross References

RefSeq

NP_008846.2

OpenTargets

ENSG00000102218

GeneCards

O75695

HPA

ENSG00000102218-RP2

Ensembl

ENST00000218340, ENSG00000102218, ENSP00000218340

PRO

O75695

Pharos - Targets

O75695

Orphanet

15223

HMDB Protein

HMDBP08623

PDB

3BH7, 2BX6, 3BH6

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9WUL7	1	ARL3 [cilium] (R-MMU-5618182)	0.743	5
IntAct:EBI-22315148 CCSB ORF ID			0.556	7
UniProt:Q8IYS1 P20D2			0.556	3
UniProt:Q9BRX9 WDR83	1	WDR83 [endosome membrane] (R-HSA-5672942)	0.534	2
UniProt:P36405 ARL3	1	ARL3 [cilium] (R-HSA-5618182)	0.499	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	11

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