Reactome | DYNLL1 [cilium]

DYNLL1 [cilium]

Stable Identifier

R-HSA-5624863

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cilium

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External Reference Information

External Reference

UniProt:P63167 DYNLL1

Gene Names

DYNLL1, DLC1, DNCL1, DNCLC1, HDLC1

Chain

chain:1-89

Reference Genes

BioGPS Gene:8655 DYNLL1

COSMIC (genes):DYNLL1 DYNLL1

CTD Gene:8655 DYNLL1

dbSNP Gene:8655 DYNLL1

ENSEMBL:ENSG00000088986 DYNLL1

HGNC:15476 DYNLL1

KEGG Gene (Homo sapiens):8655 DYNLL1

Monarch:8655 DYNLL1

NCBI Gene:8655 DYNLL1

OMIM:601562 DYNLL1

Reference Transcript

Other Identifiers

0005900731

11753833_a_at

200703_at

3059785

3434394

3434396

3434398

3434402

3434403

3434404

3434407

3434408

3434409

3434410

34891_at

3574114

3574116

7959164

7980535

8655

A_23_P65031

A_24_P124672

GE61176

GO:0000086

GO:0000278

GO:0000776

GO:0002376

GO:0003674

GO:0003774

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0005737

GO:0005739

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0005868

GO:0005874

GO:0005875

GO:0005886

GO:0005929

GO:0006810

GO:0006888

GO:0006914

GO:0006915

GO:0007017

GO:0007049

GO:0008150

GO:0008180

GO:0008219

GO:0009056

GO:0010389

GO:0015031

GO:0016020

GO:0016032

GO:0016192

GO:0016236

GO:0019886

GO:0021762

GO:0022607

GO:0030286

GO:0030705

GO:0031410

GO:0032991

GO:0035735

GO:0042326

GO:0043226

GO:0043312

GO:0044403

GO:0045505

GO:0048856

GO:0051959

GO:0070821

GO:0072686

GO:0097542

GO:0097711

GO:0101003

GO:2000582

ILMN_2300186

PH_hs_0035324

U32944_at

g4505812_3p_at

Participant Of

hasMember

dynein-2 light chains [cilium]

Other forms of this molecule

DYNLL1 [cytosol]

DYNLL1 [plasma membrane]

DYNLL1 [ficolin-1-rich granule membrane]

DYNLL1 [tertiary granule membrane]

DYNLL1 [ciliary tip]

Inferred To

Homologues of DYNLL1 [cilium] (Caenorhabditis elegans)

dlc-5 [cilium] (Caenorhabditis elegans)

dlc-3 [cilium] (Caenorhabditis elegans)

Dynll1 [cilium] (Mus musculus)

Dynll1 [cilium] (Rattus norvegicus)

dlc-1 [cilium] (Caenorhabditis elegans)

dlc-4 [cilium] (Caenorhabditis elegans)

DYNLL1 [cilium] (Canis familiaris)

DYNLL1 [cilium] (Gallus gallus)

DYNLL1 [cilium] (Sus scrofa)

dlc-2 [cilium] (Caenorhabditis elegans)

ctp [cilium] (Drosophila melanogaster)

Cross References

RefSeq

NP_003737.1, NP_001032583.1, NP_001032584.1

Target Pathogen

5b354852be737e166372ea25

OpenTargets

ENSG00000088986

HPA

ENSG00000088986-DYNLL1

GeneCards

P63167

Ensembl

ENST00000548342, ENSP00000242577, ENSP00000446614, ENSP00000376296, ENST00000549989, ENSP00000447907, ENST00000392508, ENST00000392509, ENST00000242577, ENSP00000376297, ENSG00000088986

PRO

P63167

HMDB Protein

HMDBP10685

PDB

3ZKE, 6RLB, 6GZJ, 6SC2, 1CMI, 6GZL, 3ZKF

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	10
UniProt:Q13153 PAK1	6	p-S144-PAK1 [cytosol] (R-HSA-451339) Active PAK1 [cytosol] (R-HSA-8964622) PAK1 [plasma membrane] (R-HSA-3928409) p-S144,T423-PAK1 [plasma membrane] (R-HSA-3928472) PAK1 [cytosol] (R-HSA-162629) p-S144,T423-PAK1 [cytosol] (R-HSA-399819)	0.666	4
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.632	6
UniProt:Q96LC9 BMF	3	p-BMF(1-89) [cytosol] (R-HSA-140529) BMF [plasma membrane] (R-HSA-140209) p-BMF [mitochondrial outer membrane] (R-HSA-3145026)	0.556	3
UniProt:O96015 DNAL4	1	DNAL4 [plasma membrane] (R-HSA-177484)	0.556	3
UniProt:Q9C0C7 AMBRA1	2	p-AMBRA1 [cytosol] (R-HSA-1632854) AMBRA1 [cytosol] (R-HSA-1632831)	0.508	2
UniProt:Q14677 CLINT1	1	CLINT1 [cytosol] (R-HSA-429811)	0.508	2
UniProt:Q16656 NRF1	1	NRF1 [nucleoplasm] (R-HSA-1592205)	0.508	2
UniProt:P98170 XIAP	3	XIAP [nucleoplasm] (R-HSA-3322366) K48pUb-XIAP [cytosol] (R-HSA-5675477) XIAP [cytosol] (R-HSA-50849)	0.508	2
UniProt:Q9NR28 DIABLO	2	DIABLO [mitochondrial intermembrane space] (R-HSA-64637) DIABLO [cytosol] (R-HSA-114298)	0.508	2