Reactome | IFT46 [ciliary tip]

IFT46 [ciliary tip]

Stable Identifier

R-HSA-5625359

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ciliary tip

Synonyms

IFT-B 46, IFT B

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NQC8 IFT46

Gene Names

IFT46, C11orf2, C11orf60

Chain

chain:1-304

Reference Genes

BioGPS Gene:56912 IFT46

COSMIC (genes):IFT46 IFT46

CTD Gene:56912 IFT46

dbSNP Gene:56912 IFT46

ENSEMBL:ENSG00000118096 IFT46

ENSEMBL_homo_sapiens_GENE:ENSG00000118096.10 IFT46

HGNC:26146 IFT46

KEGG Gene (Homo sapiens):56912 IFT46

Monarch:56912 IFT46

NCBI Gene:56912 IFT46

OMIM:620506 IFT46

UCSC:Q9NQC8 IFT46

Reference Transcript

Other Identifiers

11744495_a_at

16745041

218483_PM_s_at

218483_s_at

3393835

3393836

3393838

3393839

3393840

3393842

3393843

3393844

3393845

3393847

3393848

3393850

3393852

3393853

3393857

3393859

56912

7952069

90232_s_at

91183_at

GE88283

GO:0003674

GO:0005515

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0005929

GO:0007018

GO:0008150

GO:0030992

GO:0031514

GO:0035720

GO:0036064

GO:0042073

GO:0042995

GO:0043226

GO:0044782

GO:0050821

GO:0060271

GO:0097542

GO:0120025

HMNXSV003041671

ILMN_1677080

PH_hs_0016412

TC11002351.hg

g9910357_3p_a_at

Participates

as a component of

IFT B* [ciliary tip] (Homo sapiens)

Other forms of this molecule

IFT46 [cilium]

Inferred To

dyf-6 [ciliary tip] (Caenorhabditis elegans)

IFT46 [ciliary tip] (Bos taurus)

IFT46 [ciliary tip] (Canis familiaris)

IFT46 [ciliary tip] (Gallus gallus)

IFT46 [ciliary tip] (Sus scrofa)

Ift46 [ciliary tip] (Mus musculus)

Ift46 [ciliary tip] (Rattus norvegicus)

Cross References

RefSeq

XP_016873506.1, XP_011541208.1, XP_016873507.1, XP_011541207.1, NP_001162089.1, NP_064538.3

OpenTargets

ENSG00000118096

GeneCards

Q9NQC8

HPA

ENSG00000118096-IFT46

Ensembl

ENSP00000264020, ENSP00000264021, ENST00000264021, ENST00000264020, ENSG00000118096

PRO

Q9NQC8

Pharos - Targets

Q9NQC8

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13099 IFT88	8	IFT88 [ciliary tip] (R-HSA-5625371) PolyUb-Misfolded IFT88 [late endosome lumen] (R-HSA-9660031) IFT88 [cilium] (R-HSA-5610385) PolyUb-Misfolded IFT88 [lysosomal lumen] (R-HSA-9660026) PolyUb-Misfolded IFT88 [cytosol] (R-HSA-9641125) Ub-Misfolded IFT88 [cytosol] (R-HSA-9641114) Misfolded IFT88 [cytosol] (R-HSA-9640115) Misfolded IFT88 [cilium] (R-HSA-9640106)	0.724	8
UniProt:Q9Y547 HSPB11	2	HSPB11 [ciliary tip] (R-HSA-5625342) HSPB11 [cilium] (R-HSA-5617628)	0.69	6
UniProt:Q9BW83 IFT27	2	IFT27 [cilium] (R-HSA-5617621) IFT27 [ciliary tip] (R-HSA-5625357)	0.69	6
UniProt:Q9UG01 IFT172	2	IFT172 [ciliary tip] (R-HSA-5625353) IFT172 [cilium] (R-HSA-5610383)	0.69	6
UniProt:Q9P2H3 IFT80	2	IFT80 [cilium] (R-HSA-5617613) IFT80 [ciliary tip] (R-HSA-5625367)	0.638	5
UniProt:Q9H7X7 IFT22	2	RABL5 [cilium] (R-HSA-5617605) RABL5 [ciliary tip] (R-HSA-5625388)	0.638	4
UniProt:A0AVF1 TTC26	2	TTC26 [ciliary tip] (R-HSA-5637962) TTC26 [cilium] (R-HSA-5637963)	0.638	4
UniProt:Q96LB3 IFT74	2	IFT74 [cilium] (R-HSA-5617616) IFT74 [ciliary tip] (R-HSA-5625364)	0.638	5
UniProt:Q8N4P2 IFT70B	2	TTC30B [ciliary tip] (R-HSA-5637970) TTC30B [cilium] (R-HSA-5637971)	0.638	4
UniProt:Q9Y366 IFT52	2	IFT52 [ciliary tip] (R-HSA-5625360) IFT52 [cilium] (R-HSA-5610387)	0.638	4
UniProt:Q86WT1 IFT70A	2	TTC30A [ciliary tip] (R-HSA-5637966) TTC30A [cilium] (R-HSA-5637968)	0.638	5
UniProt:Q8WYA0 IFT81	2	IFT81 [cilium] (R-HSA-5617769) IFT81 [ciliary tip] (R-HSA-5625369)	0.638	4
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.508	2
UniProt:P52429 DGKE	1	DGKE [plasma membrane] (R-HSA-426061)	0.508	2
UniProt:Q96AJ1 CLUAP1	2	CLUAP [ciliary tip] (R-HSA-5637957) CLUAP [cilium] (R-HSA-5637960)	0.508	2
UniProt:Q9NWB7 IFT57	2	IFT57 [cilium] (R-HSA-5610389) IFT57 [ciliary tip] (R-HSA-5625363)	0.508	3
UniProt:Q8IY31 IFT20	3	IFT20 [cilium] (R-HSA-5617624) IFT20 [Golgi membrane] (R-HSA-5617625) IFT20 [ciliary tip] (R-HSA-5625355)	0.508	2

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