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GOPC [Golgi-associated vesicle membrane]
Stable Identifier
R-HSA-5627067
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi-associated vesicle membrane
Synonyms
Golgi-associated PDZ and coiled-coil motif-containing protein, PIST, CAL, FIG
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases regulate CFTR trafficking (Homo sapiens)
GOPC promotes translocation of CFTR to lysosomes (Homo sapiens)
GOPC dimer [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC dimer [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC [Golgi-associated vesicle membrane] (Homo sapiens)
RHOQ binds GOPC:CFTR (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC dimer [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC [Golgi-associated vesicle membrane] (Homo sapiens)
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC dimer [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC [Golgi-associated vesicle membrane] (Homo sapiens)
RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Homo sapiens)
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC dimer [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC [Golgi-associated vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HD26 GOPC
Gene Names
GOPC, CAL, FIG
Chain
initiator methionine:1, chain:2-462
Reference Genes
BioGPS Gene:57120 GOPC
COSMIC (genes):GOPC GOPC
CTD Gene:57120 GOPC
dbSNP Gene:57120 GOPC
ENSEMBL:ENSG00000047932 GOPC
HGNC:17643 GOPC
KEGG Gene (Homo sapiens):57120 GOPC
Monarch:57120 GOPC
NCBI Gene:57120 GOPC
OMIM:606845 GOPC
UCSC:Q9HD26 GOPC
Reference Transcript
RefSeq:NM_001017408.2 GOPC
RefSeq:NM_020399.3 GOPC
Other Identifiers
0002260044
11741271_a_at
11741272_a_at
17023051
19477
225022_at
225023_at
227214_at
227215_at
24018
2971379
2971380
2971381
2971382
2971385
2971386
2971387
2971388
2971390
2971391
2971392
2971395
2971399
2971400
2971401
2971402
2DC2
2LOB
45322_at
4E34
4E35
4JOE
4JOF
4JOG
4JOH
4JOJ
4JOK
4JOP
4JOR
4K6Y
4K72
4K75
4K76
4K78
4NMO
4NMP
4NMQ
4NMR
4NMS
4NMT
4NMV
4Q6H
4Q6S
57120
59685_s_at
5IC3
5K4F
74349_at
8129181
88844_at
A_23_P336040
A_23_P58877
AAG00572
AAH09553
AAK57733
AAL47160
AB209385
AF287894
AF450008
AL589939
AY033606
BAD92622
BC009553
CCDS34523
CCDS5117
CH471051
EAW48205
ENSG00000047932
ENSP00000052569
ENSP00000357484
ENST00000052569
ENST00000052569.10
ENST00000368498
ENST00000368498.6
EntrezGene:57120
EntrezGene:GOPC
F5H1Y4
GE88507
GO:0000139
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005794
GO:0005886
GO:0006810
GO:0006888
GO:0006893
GO:0008150
GO:0010360
GO:0014069
GO:0015031
GO:0016020
GO:0016192
GO:0022607
GO:0030054
GO:0030140
GO:0030425
GO:0030660
GO:0031410
GO:0032991
GO:0042995
GO:0043004
GO:0043226
GO:0044325
GO:0045176
GO:0045202
GO:0045211
GO:0051260
GO:0055085
GO:0065003
GO:2000009
GOPC
GOPC-201
GOPC-202
HGNC:17643
HPA019477
HPA024018
Hs.126268.0.S1_3p_at
Hs.126268.0.S2_3p_at
Hs.126268.0.S2_3p_x_at
Hs.23120.0.S1_3p_at
Hs.23120.0.S2_3p_at
ILMN_1695842
ILMN_2388585
IPR001478
IPR036034
IPR038879
MIM:606845
NM_001017408
NM_020399
NP_001017408
NP_065132
PF00595
PH_hs_0022918
SM00228
TC06003826.hg
TC06004056.hg
UPI000006D2C6
UPI0000070C27
XM_024446496
XP_024302264
Z85999
Participant Of
hasComponent
GOPC dimer [Golgi-associated vesicle membrane]
Other forms of this molecule
GOPC [lysosomal membrane]
GOPC [plasma membrane]
Inferred To
Homologues of GOPC [Golgi-associated vesicle membrane] (Rattus norvegicus)
GOPC [Golgi-associated vesicle membrane] (Bos taurus)
GOPC [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
GOPC [Golgi-associated vesicle membrane] (Canis familiaris)
GOPC [Golgi-associated vesicle membrane] (Danio rerio)
GOPC [Golgi-associated vesicle membrane] (Gallus gallus)
GOPC [Golgi-associated vesicle membrane] (Mus musculus)
GOPC [Golgi-associated vesicle membrane] (Rattus norvegicus)
GOPC [Golgi-associated vesicle membrane] (Sus scrofa)
GOPC [Golgi-associated vesicle membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_001017408.1
,
NP_065132.1
OpenTargets
ENSG00000047932
GeneCards
Q9HD26
PRO
Q9HD26
Orphanet
25778
HMDB Protein
HMDBP08220
PDB
4JOR
,
4JOH
,
4K78
,
4E35
,
4NMV
,
4NMQ
,
5K4F
,
4Q6H
,
2DC2
,
4JOE
,
4K6Y
,
4K72
,
4JOJ
,
4JOK
,
4NMO
,
4NMR
,
4JOF
,
4Q6S
,
2LOB
,
4K75
,
4NMS
,
4NMP
,
4JOP
,
4K76
,
4JOG
,
4E34
,
5IC3
,
4NMT
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04004 VTN
1
VTN [extracellular region]
(R-HSA-215971)
0.666
4
UniProt:P05412 JUN
4
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [nucleoplasm]
(R-HSA-450250)
JUN [cytosol]
(R-HSA-168194)
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
0.564
3
UniProt:Q99497 PARK7
7
PARK7 [nucleoplasm]
(R-HSA-3900141)
SUMO1-K130-PARK7 [nucleoplasm]
(R-HSA-4085351)
PolyUb-Misfolded PARK7 [late endosome lumen]
(R-HSA-9660005)
Ub-Misfolded PARK7 [cytosol]
(R-HSA-9641123)
Misfolded PARK7 [cytosol]
(R-HSA-9641100)
PolyUb-Misfolded PARK7 [cytosol]
(R-HSA-9641128)
PolyUb-Misfolded PARK7 [lysosomal lumen]
(R-HSA-9659997)
0.556
3
UniProt:Q15746 MYLK
2
MYLK(1-1914) [cytosol]
(R-HSA-445807)
p-S1208,S1759-MYLK(1-1914) [cytosol]
(R-HSA-5668975)
0.556
3
UniProt:P08631 HCK
1
HCK [cytosol]
(R-HSA-167708)
0.556
3
UniProt:Q6UWP7 LCLAT1
1
LCLAT1 [endoplasmic reticulum membrane]
(R-HSA-1498783)
0.556
3
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