Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
ADRBK1 [cilium]
Stable Identifier
R-HSA-5632504
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cilium
Synonyms
GRK2, BARK, BARK1
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'on' state (Homo sapiens)
Activation of SMO (Homo sapiens)
ADRBK1 binds phosphorylated SMO dimer (Homo sapiens)
ADRBK1 [cilium] (Homo sapiens)
pS588, S590, T593, S595-SMO dimer:CSNK1A1:ADRBK1 [ciliary membrane] (Homo sapiens)
ADRBK1 [cilium] (Homo sapiens)
ADRBK1 phosphorylates SMO dimer (Homo sapiens)
ADRBK1 [cilium] (Homo sapiens)
p6S, T-SMO dimer:CSNK1A1:ADRBK1 [ciliary membrane] (Homo sapiens)
ADRBK1 [cilium] (Homo sapiens)
pS588, S590, T593, S595-SMO dimer:CSNK1A1:ADRBK1 [ciliary membrane] (Homo sapiens)
ADRBK1 [cilium] (Homo sapiens)
CSNK1A1 and ADRBK1 dissociate from p-SMO dimer (Homo sapiens)
ADRBK1 [cilium] (Homo sapiens)
p6S, T-SMO dimer:CSNK1A1:ADRBK1 [ciliary membrane] (Homo sapiens)
ADRBK1 [cilium] (Homo sapiens)
External Reference Information
External Reference
UniProt:P25098 GRK2
Gene Names
GRK2, ADRBK1, BARK, BARK1
Chain
chain:1-689
Reference Genes
BioGPS Gene:156 GRK2
COSMIC (genes):GRK2 GRK2
CTD Gene:156 GRK2
dbSNP Gene:156 GRK2
ENSEMBL:ENSG00000173020 GRK2
HGNC:289 GRK2
KEGG Gene (Homo sapiens):156 GRK2
Monarch:156 GRK2
NCBI Gene:156 GRK2
OMIM:109635 GRK2
UCSC:P25098 GRK2
Reference Transcript
RefSeq:NM_001619.3 GRK2
Other Identifiers
0003120273
0100360519
11716022_at
11716023_s_at
156
16727702
201401_s_at
201402_at
3336802
3336803
3336818
3336820
3336822
3336823
3336824
3336825
3336827
3336828
3336829
3336830
3336832
3336833
3336834
3336835
3336837
3336839
3336842
3336845
3336847
3336849
3336850
3336851
3336852
3336853
3336854
3336855
3336856
38447_at
7941797
A_23_P202667
A_24_P326635
A_33_P3384392
GE81046
GE87490
GO:0000166
GO:0002026
GO:0002029
GO:0003013
GO:0003108
GO:0003674
GO:0004672
GO:0004674
GO:0004703
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0005929
GO:0006464
GO:0006468
GO:0006810
GO:0007165
GO:0007186
GO:0007213
GO:0007217
GO:0007267
GO:0007507
GO:0008150
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018107
GO:0019079
GO:0031623
GO:0031694
GO:0031755
GO:0033605
GO:0043167
GO:0043226
GO:0044403
GO:0045202
GO:0045988
GO:0046718
GO:0047696
GO:0048856
GO:0060048
GO:1901081
HMNXSV003043248
ILMN_1673330
ILMN_3307926
PH_hs_0004771
TC11000682.hg
U08438_at
g179334_3p_s_at
g6138971_3p_at
g6138971_3p_s_at
Participates
as an input of
ADRBK1 binds phosphorylated SMO dimer (Homo sapiens)
as a component of
p6S, T-SMO dimer:CSNK1A1:ADRBK1 [ciliary membrane] (Homo sapiens)
pS588, S590, T593, S595-SMO dimer:CSNK1A1:ADRBK1 [ciliary membrane] (Homo sapiens)
as an output of
CSNK1A1 and ADRBK1 dissociate from p-SMO dimer (Homo sapiens)
Other forms of this molecule
p-S29-ADRBK1 [cytosol]
GRK2 [plasma membrane]
p-S29-ADRBK1 [plasma membrane]
Inferred To
Gprk1 [cilium]
(Drosophila melanogaster)
Adrbk1 [cilium]
(Mus musculus)
Grk2 [cilium]
(Rattus norvegicus)
grk3 [cilium]
(Danio rerio)
GRK2 [cilium]
(Canis familiaris)
Cross References
RefSeq
NP_001610.2
OpenTargets
ENSG00000173020
ZINC - Substances
ARBK1_HUMAN
HPA
ENSG00000173020-GRK2
GeneCards
P25098
ZINC - Biogenic
ARBK1_HUMAN
ZINC target
P25098
Ensembl
ENSP00000312262
,
ENST00000308595
,
ENSG00000173020
PRO
P25098
ZINC - Predictions - Purchasable
ARBK1_HUMAN
HMDB Protein
HMDBP01262
PDB
6C2Y
,
3KRX
,
7K7L
,
4PNK
,
6U7C
,
5UUU
,
5WG5
,
5UKL
,
3KRW
,
5WG4
,
5UKK
,
7K7Z
,
1BAK
,
5UVC
,
5WG3
,
5HE1
,
3V5W
,
4MK0
,
3CIK
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35626 GRK3
2
ADRBK2 [plasma membrane]
(R-HSA-8852029)
ADRBK2 [cytosol]
(R-HSA-8866004)
0.564
2
UniProt:P25963 NFKBIA
10
SUMO1-K21-NFKBIA [nucleoplasm]
(R-HSA-4656935)
PolyUb-NFKBIA [cytosol]
(R-HSA-6782960)
NFKBIA [cytosol]
(R-HSA-168151)
p-S32,S36-NFKBIA [cytosol]
(R-HSA-177677)
Ub-21,22-p-S32,S36-NFKBIA [cytosol]
(R-HSA-1168581)
K48PolyUb-K21,22-p-S32,S36-IkBA [cytosol]
(R-HSA-5607659)
NFKBIA S32I [cytosol]
(R-HSA-5228846)
NFKBIA F2_M37del [cytosol]
(R-HSA-9630119)
NFKBIA M37K [cytosol]
(R-HSA-5228805)
NFKBIA [nucleoplasm]
(R-HSA-4656929)
0.558
2
UniProt:P21860 ERBB3
0.556
3
UniProt:P48730-2 CSNK1D
0.556
3
UniProt:P05067 APP
20
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:P13591 NCAM1
2
NCAM1 [plasma membrane]
(R-HSA-190987)
6xN-linked glycan core-NCAM1 [Golgi membrane]
(R-HSA-422430)
0.556
3
UniProt:P0CG48 UBC
325
UBC(533-608) [endocytic vesicle membrane]
(R-HSA-939220)
UBC(381-456) [endocytic vesicle membrane]
(R-HSA-939218)
UBC(609-684) [endocytic vesicle membrane]
(R-HSA-939223)
UBC(457-532) [endocytic vesicle membrane]
(R-HSA-939195)
UBC(153-228) [endocytic vesicle membrane]
(R-HSA-939194)
UBC(305-380) [endocytic vesicle membrane]
(R-HSA-939228)
UBC(229-304) [endocytic vesicle membrane]
(R-HSA-939177)
UBC(77-152) [endocytic vesicle membrane]
(R-HSA-939210)
UBC(1-76) [endocytic vesicle membrane]
(R-HSA-939245)
Ub-566-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783166)
Ub-338-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783121)
Ub-186-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783154)
Ub-262-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783028)
Ub-414-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783061)
Ub-110-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783158)
Ub-642-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783182)
Ub-33-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783073)
Ub-488-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783078)
Ub-291-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783193)
Ub-595-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783130)
Ub-443-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783153)
Ub-139-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783155)
Ub-63-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783094)
Ub-671-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783083)
Ub-519-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783053)
Ub-367-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783105)
Ub-215-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783137)
Ub-386-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783067)
Ub-6-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783122)
Ub-310-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783027)
Ub-234-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783157)
Ub-614-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783063)
Ub-462-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783118)
Ub-538-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783011)
Ub-158-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783140)
Ub-82-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783175)
Ub-315-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783089)
Ub-163-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783091)
Ub-543-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783060)
Ub-239-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783092)
Ub-619-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783125)
Ub-467-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783181)
Ub-11-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783104)
Ub-391-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783170)
Ub-87-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783110)
Ub-656-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783134)
Ub-124-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783120)
Ub-428-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783090)
Ub-48-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783029)
Ub-504-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783113)
Ub-200-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783150)
Ub-580-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783119)
Ub-276-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783183)
Ub-352-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783201)
Ub-29-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783064)
Ub-182-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783097)
Ub-486-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783194)
Ub-334-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783199)
Ub-638-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783188)
Ub-106-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783031)
Ub-258-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783016)
Ub-562-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783172)
Ub-410-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783077)
Ub-636-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783128)
Ub-104-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783032)
Ub-256-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783004)
Ub-484-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783156)
Ub-27-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783022)
Ub-332-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783138)
Ub-180-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783107)
Ub-408-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783108)
Ub-560-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783174)
N6-glycyl-L-lysine-UBC(457-532) [cytosol]
(R-HSA-8869048)
N6-glycyl-L-lysine-UBC(609-684) [cytosol]
(R-HSA-8869052)
N6-glycyl-L-lysine-UBC(229-304) [cytosol]
(R-HSA-8869032)
N6-glycyl-L-lysine-UBC(533-608) [cytosol]
(R-HSA-8869033)
N6-glycyl-L-lysine-UBC(153-228) [cytosol]
(R-HSA-8869035)
N6-glycyl-L-lysine-UBC(305-380) [cytosol]
(R-HSA-8869036)
N6-glycyl-L-lysine-UBC(77-152) [cytosol]
(R-HSA-8869026)
N6-glycyl-L-lysine-UBC(1-76) [cytosol]
(R-HSA-8869030)
N6-glycyl-L-lysine-UBC(381-456) [cytosol]
(R-HSA-8869031)
adenylatedG608-UBC(533-608) [nucleoplasm]
(R-HSA-8852090)
adenylatedG380-UBC(305-380) [nucleoplasm]
(R-HSA-8852093)
adenylatedG532-UBC(457-532) [nucleoplasm]
(R-HSA-8852081)
adenylatedG304-UBC(229-304) [nucleoplasm]
(R-HSA-8852050)
adenylatedG152-UBC(77-152) [nucleoplasm]
(R-HSA-8852054)
adenylatedG684-UBC(609-684) [nucleoplasm]
(R-HSA-8852105)
adenylatedG228-UBC(153-228) [nucleoplasm]
(R-HSA-8852075)
adenylatedG76-UBC(1-76) [nucleoplasm]
(R-HSA-8852044)
adenylatedG456-UBC(381-456) [nucleoplasm]
(R-HSA-8852098)
UBC [cytosol]
(R-HSA-8853531)
adenylatedG380-UBC(305-380) [cytosol]
(R-HSA-8852062)
adenylatedG608-UBC(533-608) [cytosol]
(R-HSA-8852052)
adenylatedG76-UBC(1-76) [cytosol]
(R-HSA-8852053)
adenylatedG304-UBC(229-304) [cytosol]
(R-HSA-8852117)
adenylatedG684-UBC(609-684) [cytosol]
(R-HSA-8852118)
adenylatedG152-UBC(77-152) [cytosol]
(R-HSA-8852087)
adenylatedG532-UBC(457-532) [cytosol]
(R-HSA-8852045)
adenylatedG228-UBC(153-228) [cytosol]
(R-HSA-8852111)
adenylatedG456-UBC(381-456) [cytosol]
(R-HSA-8852069)
Ub-428-UBC(381-456) [endoplasmic reticulum membrane]
(R-HSA-8943062)
Ub-656-UBC(609-684) [endoplasmic reticulum membrane]
(R-HSA-8943120)
Ub-124-UBC(77-152) [endoplasmic reticulum membrane]
(R-HSA-8943129)
Ub-48-UBC(1-76) [endoplasmic reticulum membrane]
(R-HSA-8943079)
Ub-352-UBC(305-380) [endoplasmic reticulum membrane]
(R-HSA-8943108)
Ub-504-UBC(457-532) [endoplasmic reticulum membrane]
(R-HSA-8943075)
Ub-276-UBC(229-304) [endoplasmic reticulum membrane]
(R-HSA-8943106)
Ub-580-UBC(533-608) [endoplasmic reticulum membrane]
(R-HSA-8943137)
Ub-200-UBC(153-228) [endoplasmic reticulum membrane]
(R-HSA-8943087)
UBC(1-76) [plasma membrane]
(R-HSA-3149469)
UBC(457-532) [plasma membrane]
(R-HSA-3149468)
UBC(153-228) [plasma membrane]
(R-HSA-3149467)
UBC(609-684) [plasma membrane]
(R-HSA-3149466)
UBC(77-152) [plasma membrane]
(R-HSA-3149465)
UBC(229-304) [plasma membrane]
(R-HSA-3149464)
UBC(533-608) [plasma membrane]
(R-HSA-3149462)
UBC(381-456) [plasma membrane]
(R-HSA-3149459)
UBC(305-380) [plasma membrane]
(R-HSA-3149458)
UBC(1-76) [endosome membrane]
(R-HSA-939187)
UBC(533-608) [endosome membrane]
(R-HSA-939221)
UBC(77-152) [endosome membrane]
(R-HSA-939161)
UBC(305-380) [endosome membrane]
(R-HSA-939196)
UBC(457-532) [endosome membrane]
(R-HSA-939199)
UBC(381-456) [endosome membrane]
(R-HSA-939166)
UBC(153-228) [endosome membrane]
(R-HSA-939170)
UBC(609-684) [endosome membrane]
(R-HSA-939237)
UBC(229-304) [endosome membrane]
(R-HSA-939172)
UBC(77-152) [endoplasmic reticulum membrane]
(R-HSA-8943095)
UBC(381-456) [endoplasmic reticulum membrane]
(R-HSA-8943126)
UBC(533-608) [endoplasmic reticulum membrane]
(R-HSA-8943061)
UBC(609-684) [endoplasmic reticulum membrane]
(R-HSA-8943135)
UBC(229-304) [endoplasmic reticulum membrane]
(R-HSA-8943103)
UBC(153-228) [endoplasmic reticulum membrane]
(R-HSA-8943068)
UBC(1-76) [endoplasmic reticulum membrane]
(R-HSA-8943077)
UBC(305-380) [endoplasmic reticulum membrane]
(R-HSA-8943084)
UBC(457-532) [endoplasmic reticulum membrane]
(R-HSA-8943112)
Ub-29-UBC(1-76) [cytosol]
(R-HSA-5689165)
Ub-258-UBC(229-304) [cytosol]
(R-HSA-5689167)
Ub-334-UBC(305-380) [cytosol]
(R-HSA-5689166)
Ub-410-UBC(381-456) [cytosol]
(R-HSA-5689185)
Ub-486-UBC(457-532) [cytosol]
(R-HSA-5689176)
Ub-562-UBC(533-608) [cytosol]
(R-HSA-5689151)
Ub-106-UBC(77-152) [cytosol]
(R-HSA-5689183)
Ub-182-UBC(153-228) [cytosol]
(R-HSA-5689169)
Ub-638-UBC(609-684) [cytosol]
(R-HSA-5689136)
Ub-310-UBC(305-380) [cytosol]
(R-HSA-5689097)
Ub-6-UBC(1-76) [cytosol]
(R-HSA-5689091)
Ub-462-UBC(457-532) [cytosol]
(R-HSA-5689092)
Ub-386-UBC(381-456) [cytosol]
(R-HSA-5689086)
Ub-538-UBC(533-608) [cytosol]
(R-HSA-5689104)
Ub-158-UBC(153-228) [cytosol]
(R-HSA-5689107)
Ub-614-UBC(609-684) [cytosol]
(R-HSA-5689076)
Ub-234-UBC(229-304) [cytosol]
(R-HSA-5689110)
Ub-82-UBC(77-152) [cytosol]
(R-HSA-5689078)
Ub-110-UBC(77-152) [cytosol]
(R-HSA-5689196)
Ub-33-UBC(1-76) [cytosol]
(R-HSA-5689134)
Ub-488-UBC(457-532) [cytosol]
(R-HSA-5689153)
Ub-338-UBC(305-380) [cytosol]
(R-HSA-5689152)
Ub-642-UBC(609-684) [cytosol]
(R-HSA-5689218)
Ub-414-UBC(381-456) [cytosol]
(R-HSA-5689157)
Ub-262-UBC(229-304) [cytosol]
(R-HSA-5689150)
Ub-566-UBC(533-608) [cytosol]
(R-HSA-5689205)
Ub-186-UBC(153-228) [cytosol]
(R-HSA-5689140)
Ub-256-UBC(229-304) [cytosol]
(R-HSA-5689135)
Ub-180-UBC(153-228) [cytosol]
(R-HSA-5689221)
Ub-104-UBC(77-152) [cytosol]
(R-HSA-5689189)
Ub-484-UBC(457-532) [cytosol]
(R-HSA-5689220)
Ub-560-UBC(533-608) [cytosol]
(R-HSA-5689145)
Ub-636-UBC(609-684) [cytosol]
(R-HSA-5689144)
Ub-332-UBC(305-380) [cytosol]
(R-HSA-5689211)
Ub-27-UBC(1-76) [cytosol]
(R-HSA-5689179)
Ub-408-UBC(381-456) [cytosol]
(R-HSA-5689182)
Ub-87-UBC(77-152) [cytosol]
(R-HSA-3095920)
Ub-163-UBC(153-228) [cytosol]
(R-HSA-3095924)
Ub-619-UBC(609-684) [cytosol]
(R-HSA-3095925)
Ub-467-UBC(457-532) [cytosol]
(R-HSA-3095935)
Ub-11-UBC(1-76) [cytosol]
(R-HSA-3095906)
Ub-543-UBC(533-608) [cytosol]
(R-HSA-3095912)
Ub-391-UBC(381-456) [cytosol]
(R-HSA-3095914)
Ub-315-UBC(305-380) [cytosol]
(R-HSA-3095916)
Ub-239-UBC(229-304) [cytosol]
(R-HSA-3095919)
Ub-519-UBC(457-532) [endosome membrane]
(R-HSA-939227)
Ub-367-UBC(305-380) [endosome membrane]
(R-HSA-939162)
Ub-291-UBC(229-304) [endosome membrane]
(R-HSA-939226)
Ub-443-UBC(381-456) [endosome membrane]
(R-HSA-939204)
Ub-215-UBC(153-228) [endosome membrane]
(R-HSA-939175)
Ub-63-UBC(1-76) [endosome membrane]
(R-HSA-939174)
Ub-595-UBC(533-608) [endosome membrane]
(R-HSA-939242)
Ub-139-UBC(77-152) [endosome membrane]
(R-HSA-939244)
Ub-671-UBC(609-684) [endosome membrane]
(R-HSA-939183)
Ub-291-UBC(229-304) [plasma membrane]
(R-HSA-939859)
Ub-595-UBC(533-608) [plasma membrane]
(R-HSA-939858)
Ub-367-UBC(305-380) [plasma membrane]
(R-HSA-939861)
Ub-63-UBC(1-76) [plasma membrane]
(R-HSA-939860)
Ub-139-UBC(77-152) [plasma membrane]
(R-HSA-939865)
Ub-215-UBC(153-228) [plasma membrane]
(R-HSA-939864)
Ub-519-UBC(457-532) [plasma membrane]
(R-HSA-939845)
Ub-671-UBC(609-684) [plasma membrane]
(R-HSA-939846)
Ub-443-UBC(381-456) [plasma membrane]
(R-HSA-939848)
Ub-408-UBC(381-456) [nucleoplasm]
(R-HSA-6782681)
Ub-484-UBC(457-532) [nucleoplasm]
(R-HSA-6782650)
Ub-104-UBC(77-152) [nucleoplasm]
(R-HSA-6782651)
Ub-256-UBC(229-304) [nucleoplasm]
(R-HSA-6782641)
Ub-180-UBC(153-228) [nucleoplasm]
(R-HSA-6782603)
Ub-560-UBC(533-608) [nucleoplasm]
(R-HSA-6782637)
Ub-27-UBC(1-76) [nucleoplasm]
(R-HSA-6782625)
Ub-636-UBC(609-684) [nucleoplasm]
(R-HSA-6782597)
Ub-332-UBC(305-380) [nucleoplasm]
(R-HSA-6782630)
Ub-638-UBC(609-684) [nucleoplasm]
(R-HSA-6782680)
Ub-258-UBC(229-304) [nucleoplasm]
(R-HSA-6782621)
Ub-562-UBC(533-608) [nucleoplasm]
(R-HSA-6782672)
Ub-410-UBC(381-456) [nucleoplasm]
(R-HSA-6782642)
Ub-182-UBC(153-228) [nucleoplasm]
(R-HSA-6782678)
Ub-106-UBC(77-152) [nucleoplasm]
(R-HSA-6782602)
Ub-334-UBC(305-380) [nucleoplasm]
(R-HSA-6782638)
Ub-29-UBC(1-76) [nucleoplasm]
(R-HSA-6782659)
Ub-486-UBC(457-532) [nucleoplasm]
(R-HSA-6782661)
Ub-48-UBC(1-76) [nucleoplasm]
(R-HSA-6782524)
Ub-428-UBC(381-456) [nucleoplasm]
(R-HSA-6782462)
Ub-504-UBC(457-532) [nucleoplasm]
(R-HSA-6782512)
Ub-276-UBC(229-304) [nucleoplasm]
(R-HSA-6782482)
Ub-200-UBC(153-228) [nucleoplasm]
(R-HSA-6782487)
Ub-656-UBC(609-684) [nucleoplasm]
(R-HSA-6782474)
Ub-580-UBC(533-608) [nucleoplasm]
(R-HSA-6782477)
Ub-124-UBC(77-152) [nucleoplasm]
(R-HSA-6782498)
Ub-352-UBC(305-380) [nucleoplasm]
(R-HSA-6782467)
Ub-467-UBC(457-532) [nucleoplasm]
(R-HSA-6782619)
Ub-163-UBC(153-228) [nucleoplasm]
(R-HSA-6782622)
Ub-11-UBC(1-76) [nucleoplasm]
(R-HSA-6782609)
Ub-87-UBC(77-152) [nucleoplasm]
(R-HSA-6782632)
Ub-239-UBC(229-304) [nucleoplasm]
(R-HSA-6782669)
Ub-543-UBC(533-608) [nucleoplasm]
(R-HSA-6782594)
Ub-391-UBC(381-456) [nucleoplasm]
(R-HSA-6782626)
Ub-315-UBC(305-380) [nucleoplasm]
(R-HSA-6782660)
Ub-619-UBC(609-684) [nucleoplasm]
(R-HSA-6782662)
Ub-186-UBC(153-228) [nucleoplasm]
(R-HSA-6782617)
Ub-338-UBC(305-380) [nucleoplasm]
(R-HSA-6782620)
Ub-33-UBC(1-76) [nucleoplasm]
(R-HSA-6782653)
Ub-110-UBC(77-152) [nucleoplasm]
(R-HSA-6782590)
Ub-262-UBC(229-304) [nucleoplasm]
(R-HSA-6782640)
Ub-642-UBC(609-684) [nucleoplasm]
(R-HSA-6782674)
Ub-566-UBC(533-608) [nucleoplasm]
(R-HSA-6782646)
Ub-414-UBC(381-456) [nucleoplasm]
(R-HSA-6782636)
Ub-488-UBC(457-532) [nucleoplasm]
(R-HSA-6782599)
UBC(229-304) [nucleoplasm]
(R-HSA-939857)
UBC(381-456) [nucleoplasm]
(R-HSA-939856)
UBC(305-380) [nucleoplasm]
(R-HSA-939863)
UBC(457-532) [nucleoplasm]
(R-HSA-939862)
UBC(533-608) [nucleoplasm]
(R-HSA-939866)
UBC(77-152) [nucleoplasm]
(R-HSA-939869)
UBC(609-684) [nucleoplasm]
(R-HSA-939868)
UBC(1-76) [nucleoplasm]
(R-HSA-939871)
UBC(153-228) [nucleoplasm]
(R-HSA-939853)
Ub-124-UBC(77-152) [nucleoplasm]
(R-HSA-5683048)
Ub-580-UBC(533-608) [nucleoplasm]
(R-HSA-5683050)
Ub-428-UBC(381-456) [nucleoplasm]
(R-HSA-5683041)
Ub-276-UBC(229-304) [nucleoplasm]
(R-HSA-5683042)
Ub-352-UBC(305-380) [nucleoplasm]
(R-HSA-5683045)
Ub-200-UBC(153-228) [nucleoplasm]
(R-HSA-5683046)
Ub-48-UBC(1-76) [nucleoplasm]
(R-HSA-5683033)
Ub-656-UBC(609-684) [nucleoplasm]
(R-HSA-5683035)
Ub-504-UBC(457-532) [nucleoplasm]
(R-HSA-5683039)
Ub-671-UBC(609-684) [nucleoplasm]
(R-HSA-6782523)
Ub-215-UBC(153-228) [nucleoplasm]
(R-HSA-6782491)
Ub-63-UBC(1-76) [nucleoplasm]
(R-HSA-6782492)
Ub-443-UBC(381-456) [nucleoplasm]
(R-HSA-6782480)
Ub-367-UBC(305-380) [nucleoplasm]
(R-HSA-6782479)
Ub-139-UBC(77-152) [nucleoplasm]
(R-HSA-6782496)
Ub-519-UBC(457-532) [nucleoplasm]
(R-HSA-6782497)
Ub-595-UBC(533-608) [nucleoplasm]
(R-HSA-6782499)
Ub-291-UBC(229-304) [nucleoplasm]
(R-HSA-6782500)
Ub-82-UBC(77-152) [nucleoplasm]
(R-HSA-6782675)
Ub-6-UBC(1-76) [nucleoplasm]
(R-HSA-6782611)
Ub-234-UBC(229-304) [nucleoplasm]
(R-HSA-6782677)
Ub-158-UBC(153-228) [nucleoplasm]
(R-HSA-6782645)
Ub-310-UBC(305-380) [nucleoplasm]
(R-HSA-6782614)
Ub-538-UBC(533-608) [nucleoplasm]
(R-HSA-6782664)
Ub-462-UBC(457-532) [nucleoplasm]
(R-HSA-6782634)
Ub-386-UBC(381-456) [nucleoplasm]
(R-HSA-6782605)
Ub-614-UBC(609-684) [nucleoplasm]
(R-HSA-6782657)
UBC(609-684) [late endosome lumen]
(R-HSA-9660012)
UBC(153-228) [late endosome lumen]
(R-HSA-9659979)
UBC(305-380) [late endosome lumen]
(R-HSA-9660033)
UBC(77-152) [late endosome lumen]
(R-HSA-9659992)
UBC(533-608) [late endosome lumen]
(R-HSA-9659993)
UBC(229-304) [late endosome lumen]
(R-HSA-9659994)
UBC(457-532) [late endosome lumen]
(R-HSA-9659995)
UBC(381-456) [late endosome lumen]
(R-HSA-9660023)
UBC(1-76) [late endosome lumen]
(R-HSA-9659985)
Ub-48-UBC(1-76) [cytosol]
(R-HSA-939219)
Ub-656-UBC(609-684) [cytosol]
(R-HSA-939255)
Ub-428-UBC(381-456) [cytosol]
(R-HSA-939190)
Ub-504-UBC(457-532) [cytosol]
(R-HSA-939257)
Ub-580-UBC(533-608) [cytosol]
(R-HSA-939256)
Ub-276-UBC(229-304) [cytosol]
(R-HSA-939207)
Ub-124-UBC(77-152) [cytosol]
(R-HSA-939209)
Ub-200-UBC(153-228) [cytosol]
(R-HSA-939179)
Ub-352-UBC(305-380) [cytosol]
(R-HSA-939181)
UBC(457-532) [cytosol]
(R-HSA-939184)
UBC(1-76) [cytosol]
(R-HSA-939188)
UBC(381-456) [cytosol]
(R-HSA-939191)
UBC(229-304) [cytosol]
(R-HSA-939192)
UBC(153-228) [cytosol]
(R-HSA-939258)
UBC(609-684) [cytosol]
(R-HSA-939165)
UBC(77-152) [cytosol]
(R-HSA-939164)
UBC(305-380) [cytosol]
(R-HSA-939232)
UBC(533-608) [cytosol]
(R-HSA-939239)
UBC(1-76) [lysosomal lumen]
(R-HSA-9659981)
UBC(305-380) [lysosomal lumen]
(R-HSA-9660008)
UBC(77-152) [lysosomal lumen]
(R-HSA-9659978)
UBC(609-684) [lysosomal lumen]
(R-HSA-9660020)
UBC(153-228) [lysosomal lumen]
(R-HSA-9659988)
UBC(457-532) [lysosomal lumen]
(R-HSA-9659989)
UBC(381-456) [lysosomal lumen]
(R-HSA-9659984)
UBC(229-304) [lysosomal lumen]
(R-HSA-9660018)
UBC(533-608) [lysosomal lumen]
(R-HSA-9659987)
Ub-215-UBC(153-228) [cytosol]
(R-HSA-939186)
Ub-139-UBC(77-152) [cytosol]
(R-HSA-939254)
Ub-595-UBC(533-608) [cytosol]
(R-HSA-939198)
Ub-291-UBC(229-304) [cytosol]
(R-HSA-939173)
Ub-367-UBC(305-380) [cytosol]
(R-HSA-939206)
Ub-671-UBC(609-684) [cytosol]
(R-HSA-939241)
Ub-63-UBC(1-76) [cytosol]
(R-HSA-939176)
Ub-519-UBC(457-532) [cytosol]
(R-HSA-939212)
Ub-443-UBC(381-456) [cytosol]
(R-HSA-939182)
0.524
3
UniProt:P21462 FPR1
4
FPR1 [secretory granule membrane]
(R-HSA-6800929)
FPR1 [azurophil granule membrane]
(R-HSA-6799143)
FPR1 [ficolin-1-rich granule membrane]
(R-HSA-6800878)
FPR1 [plasma membrane]
(R-HSA-375450)
0.499
3
UniProt:Q13635 PTCH1
4
ub-PTCH1 [endocytic vesicle membrane]
(R-HSA-5632520)
PTCH1 [plasma membrane]
(R-HSA-445133)
ub-PTCH1 [ciliary membrane]
(R-HSA-5632517)
PTCH1 [ciliary membrane]
(R-HSA-5610415)
0.499
2
UniProt:Q9UBN7 HDAC6
5
HDAC6 [late endosome lumen]
(R-HSA-9659980)
HDAC6 [nucleoplasm]
(R-HSA-351589)
HDAC6 [cytosol]
(R-HSA-5324660)
HDAC6 [cytosol]
(R-HSA-9646404)
HDAC6 [lysosomal lumen]
(R-HSA-9660002)
0.463
2
UniProt:P00533 EGFR
59
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR M766_A767insASV [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR D770_N771insNPH [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR V738_K739insKIPVAI [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
p-6Y-EGFR A289V [plasma membrane]
(R-HSA-1996334)
p-6Y-EGFR T263P [plasma membrane]
(R-HSA-1996336)
p-6Y-EGFR G598V [plasma membrane]
(R-HSA-1996339)
p-6Y-EGFR R108K [plasma membrane]
(R-HSA-1996338)
p-6Y-EGFR A289T [plasma membrane]
(R-HSA-1996341)
p-6Y-EGFR G719C [plasma membrane]
(R-HSA-1177530)
p-6Y-EGFR A289D [plasma membrane]
(R-HSA-1996340)
p-6Y-EGFR G719A [plasma membrane]
(R-HSA-1177528)
EGFR L858R;T790M [plasma membrane]
(R-HSA-1181386)
EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1181399)
EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996322)
EGFR V738_K739insKIPVAI [plasma membrane]
(R-HSA-1996325)
EGFR M766_A767insASV [plasma membrane]
(R-HSA-1996326)
EGFR D770_N771insNPH [plasma membrane]
(R-HSA-1996317)
EGFR L858R [plasma membrane]
(R-HSA-1173212)
EGFR G719S [plasma membrane]
(R-HSA-1169418)
EGFR E746_A750del [plasma membrane]
(R-HSA-1181211)
EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228010)
EGFR A289V [plasma membrane]
(R-HSA-1996321)
EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228012)
EGFR L747_T751del [plasma membrane]
(R-HSA-1228015)
EGFR A289D [plasma membrane]
(R-HSA-1996327)
EGFR L861Q [plasma membrane]
(R-HSA-1177542)
EGFR R108K [plasma membrane]
(R-HSA-1996330)
EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228034)
EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228031)
EGFR G719A [plasma membrane]
(R-HSA-1177532)
EGFR A289T [plasma membrane]
(R-HSA-1996306)
EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228025)
EGFR G719C [plasma membrane]
(R-HSA-1177531)
EGFR T263P [plasma membrane]
(R-HSA-1996315)
EGFR G598V [plasma membrane]
(R-HSA-1996314)
EGFR L747_S752del [plasma membrane]
(R-HSA-1228016)
EGFR [endosome membrane]
(R-HSA-9611160)
p-4Y-EGFR [plasma membrane]
(R-HSA-180287)
p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR [plasma membrane]
(R-HSA-8864019)
p-Y1086,Y1101-EGFR [plasma membrane]
(R-HSA-179868)
EGFR [plasma membrane]
(R-HSA-179837)
p-6Y-EGFR [plasma membrane]
(R-HSA-179803)
0.463
3
UniProt:Q9Y2X7 GIT1
2
GIT1 [cytosol]
(R-HSA-430326)
p-Y383-GIT1 [cytosol]
(R-HSA-3928463)
0.463
5
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
![ADRBK1 [cilium] icon](/icon/R-ICO-012798.svg){kind=icon}
