TP53 binds the PTEN promoter

Stable Identifier
R-HSA-5632939
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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TP53 binds the PTEN promoter
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PTEN (phosphatase and tensin homolog deleted in chromosome 10) is a tumor suppressor gene that is deleted or mutated in a variety of human cancers. TP53 (p53) binds to the p53-binding site at the PTEN promoter level (Stambolic et al. 2001).
Literature References
PubMed ID Title Journal Year
11545734 Regulation of PTEN transcription by p53

Stambolic, V, Sas, D, Benchimol, S, Snow, B, Jang, Y, MacPherson, D, Lin, Y, Mak, TW

Mol. Cell 2001
Participants
Input
Output
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as an event of
Authored
Orlic-Milacic, M  (2014-12-23)
Reviewed
Salmena, L  (2016-08-11)
Leslie, N  (2016-09-30)
Kriplani, N  (2016-09-30)
Carracedo, A  (2016-08-11)
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Wang, PY  (2014-12-30)
Hwang, PM  (2014-12-30)
Kang, JG  (2014-12-30)
Created
Orlic-Milacic, M  (2014-10-29)
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