Reactome | TRAF1 [cytosol]

TRAF1 [cytosol]

Stable Identifier

R-HSA-5634163

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

TNF receptor associated factor 1, Epstein-Barr virus-induced protein 6, EBI6

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13077 TRAF1

Gene Names

TRAF1, EBI6

Chain

chain:1-416

Reference Genes

BioGPS Gene:7185 TRAF1

COSMIC (genes):TRAF1 TRAF1

CTD Gene:7185 TRAF1

dbSNP Gene:7185 TRAF1

ENSEMBL:ENSG00000056558 TRAF1

HGNC:12031 TRAF1

KEGG Gene (Homo sapiens):7185 TRAF1

Monarch:7185 TRAF1

NCBI Gene:7185 TRAF1

OMIM:601711 TRAF1

UCSC:Q13077 TRAF1

Reference Transcript

Other Identifiers

0002630041

11721587_at

11721588_at

11721589_a_at

17097941

205599_at

235116_at

3223741

3223742

3223743

3223744

3223745

3223748

3223749

3223750

3223753

3223754

3223759

3223764

3223765

3223767

3223770

3223771

7185

74382_g_at

74384_at

76878_at

8163825

848_at

849_g_at

90942_at

A_23_P216970

A_24_P89891

GE58373

GO:0003674

GO:0005164

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005829

GO:0005886

GO:0006464

GO:0006915

GO:0006950

GO:0007165

GO:0008150

GO:0008219

GO:0008270

GO:0009058

GO:0009898

GO:0010803

GO:0019899

GO:0022607

GO:0031625

GO:0031996

GO:0033209

GO:0034641

GO:0042802

GO:0042981

GO:0043122

GO:0043167

GO:0046330

GO:0051092

GO:0065003

GO:0070534

GO:2001236

Hs.129024.0.A1_3p_at

ILMN_1698218

ILMN_2171789

PH_hs_0032218

TC09001541.hg

U19261_at

g5032192_3p_at

Participant Of

input

hasComponent

TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane]

This entity regulates

Positively

TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2)

Other forms of this molecule

TRAF1(1-163) [cytosol]

TRAF1(164-416) [cytosol]

Inferred To

trf-2 [cytosol] (Caenorhabditis elegans)

TRAF1 [cytosol] (Canis familiaris)

TRAF1 [cytosol] (Dictyostelium discoideum)

TRAF1 [cytosol] (Gallus gallus)

TRAF1 [cytosol] (Sus scrofa)

TRAF1 [cytosol] (Xenopus tropicalis)

Traf1 [cytosol] (Mus musculus)

Traf1 [cytosol] (Rattus norvegicus)

Homologues of TRAF1 [cytosol] (Dictyostelium discoideum)

traf1 [cytosol] (Danio rerio)

Traf-like [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_001177876.1, NP_005649.1, NP_001177874.1

OpenTargets

ENSG00000056558

HPA

ENSG00000056558-TRAF1

GeneCards

Q13077

Ensembl

ENST00000373887, ENSP00000362994, ENST00000540010, ENSP00000443183, ENSG00000056558, ENSP00000438583, ENST00000546084

PRO

Q13077

PDB

5H10, 5E1T, 3M0D

Interactors (214)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y4K3 TRAF6	8	TRAF6 [cytosol] (R-HSA-166366) K48polyUb-TRAF6 [cytosol] (R-HSA-6783233) K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) TRAF6 [plasma membrane] (R-HSA-936955) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227) TRAF6 [endosome membrane] (R-HSA-450272) PolyUb-TRAF6 [cytosol] (R-HSA-6782845)	0.911	17
UniProt:Q12933 TRAF2	5	K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.855	11
UniProt:Q15555 MARE2			0.841	9
UniProt:Q9BVL2 NUP58			0.841	9
UniProt:Q13546 RIPK1	14	PolyUb-RIPK1 [cytosol] (R-HSA-6783197) K48polyUb-RIPK1 [cytosol] (R-HSA-6783308) RIPK1 D324N [cytosol] (R-HSA-9693930) RIPK1 D324Y [cytosol] (R-HSA-9693931) RIPK1 D324V [cytosol] (R-HSA-9693927) RIPK1 D324H [cytosol] (R-HSA-9693922) RIPK1 [plasma membrane] (R-HSA-937073) K63pUb-K377-RIP1 [cytosol] (R-HSA-5212672) RIPK1(1-324) [cytosol] (R-HSA-5212664) RIPK1(325-671) [cytosol] (R-HSA-5212671) p-S166-RIPK1 [cytosol] (R-HSA-5218872) K63polyUb-RIPK1 [cytosol] (R-HSA-937021) RIPK1 [endosome membrane] (R-HSA-450326) RIPK1 [cytosol] (R-HSA-168651)	0.798	8
UniProt:Q9BWG6 SCNM1			0.795	8
UniProt:Q6PF18 MORN3			0.795	8
UniProt:P56279 TCL1A			0.795	8
UniProt:Q13077 TRAF1	3	TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1 [cytosol] (R-HSA-5634163) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.785	5
UniProt:P20618 PSMB1	5	PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [nucleoplasm] (R-HSA-174347) PSMB1 [cytosol] (R-HSA-68738)	0.781	7
UniProt:Q9H8Y8 GORASP2	2	p-T222,T225-GORASP2 [Golgi membrane] (R-HSA-2422965) GORASP2 [Golgi membrane] (R-HSA-2422385)	0.781	7
UniProt:Q9H7H0 MET17			0.781	7
UniProt:Q8IYI8 ZNF440	1	ZNF440 [nucleoplasm] (R-HSA-1247548)	0.781	7
UniProt:Q8TBZ5 ZN502			0.781	7
UniProt:Q96KM6 Z512B			0.781	7
UniProt:Q13490 BIRC2	5	K48pUb-BIRC2 [cytosol] (R-HSA-5675479) K63polyUb-BIRC2 [cytosol] (R-HSA-5668512) BIRC2(1-372) [cytosol] (R-HSA-202913) BIRC2(373-618) [cytosol] (R-HSA-202931) BIRC2 [cytosol] (R-HSA-50847)	0.738	5
UniProt:P42772 CDKN2B	1	CDKN2B [cytosol] (R-HSA-182586)	0.735	7
UniProt:Q8TD31-3 CCHCR1			0.718	6
UniProt:Q8TAB5 CA216			0.718	6
UniProt:P55040 GEM			0.718	6
UniProt:Q96SQ5 ZNF587	1	ZNF587 [nucleoplasm] (R-HSA-2127565)	0.718	6
UniProt:O15519 CFLAR	1	CFLAR(1-376) [cytosol] (R-HSA-51925)	0.718	6
UniProt:P17024 ZNF20	1	ZNF20 [nucleoplasm] (R-HSA-975024)	0.718	6
UniProt:Q9BT49 THAP7			0.718	6
UniProt:Q99618 CDCA3			0.718	6
UniProt:Q15973 ZNF124	1	ZNF124 [nucleoplasm] (R-HSA-975017)	0.718	6
UniProt:Q969H6 POP5	1	POP5 [nucleoplasm] (R-HSA-5696783)	0.718	6
UniProt:Q8IYX3 CC116			0.718	6
UniProt:Q8TBZ8 ZNF564	1	ZNF564 [nucleoplasm] (R-HSA-1973885)	0.718	6
UniProt:Q2TAL8 QRIC1			0.718	6
UniProt:Q01664 TFAP4			0.718	6
UniProt:Q9NX04 CA109			0.718	6
UniProt:Q9NZD8 SPG21			0.718	6
UniProt:P00540 MOS			0.718	6
UniProt:Q7RTU3 OLIG3			0.718	6
UniProt:Q9NQ94 A1CF	1	A1CF [nucleoplasm] (R-HSA-3211440)	0.718	6
UniProt:Q13188 STK3	4	p-T180-STK3(1-322) [cytosol] (R-HSA-2028696) STK3(323-491) [cytosol] (R-HSA-2028684) p-T180-STK3(1-491) [cytosol] (R-HSA-2028274) STK3(1-491) [cytosol] (R-HSA-2028280)	0.718	6
UniProt:Q15561 TEAD4	1	TEAD4 [nucleoplasm] (R-HSA-2032780)	0.718	6
UniProt:Q9UBP5 HEY2	1	HEY2 [nucleoplasm] (R-HSA-1606745)	0.718	6
UniProt:Q05516 ZBTB16	1	ZBTB16 [cytosol] (R-HSA-976047)	0.696	5
UniProt:Q08117-2 TLE5			0.696	6
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.696	5
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.696	7
UniProt:Q96EJ4 Q96EJ4			0.696	5
UniProt:P15408 FOSL2			0.696	5
UniProt:Q3B820 F161A			0.696	5
UniProt:P41182 BCL6	1	BCL6 [nucleoplasm] (R-HSA-5223066)	0.696	5
UniProt:Q13011 ECH1	2	ECH1(1-328) [cytosol] (R-HSA-9033152) ECH1(1-328) [peroxisomal matrix] (R-HSA-9033140)	0.666	4
UniProt:Q96BD5 PHF21A	1	PHF21A [nucleoplasm] (R-HSA-996754)	0.666	4
UniProt:Q8WXI9 GATAD2B	1	GATAD2B [nucleoplasm] (R-HSA-3702079)	0.666	4
UniProt:O76041 NEBL			0.666	4
UniProt:Q494U1 PKHN1			0.666	4
UniProt:Q96HB5-4 CCDC120			0.666	4
UniProt:Q7L591 DOK3	3	DOK3 [plasma membrane] (R-HSA-6801572) DOK3 [secretory granule membrane] (R-HSA-6801402) DOK3 [ficolin-1-rich granule membrane] (R-HSA-6801409)	0.666	4
UniProt:P09022 Hoxa1	1	Hoxa1 [nucleoplasm] (R-MMU-5617924)	0.592	4
UniProt:P0CG47 UBB	109	UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-110-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-186-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-182-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070) Ub-106-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783103) Ub-27-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783038) Ub-180-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783114) Ub-104-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783149) N6-glycyl-L-lysine-UBB(1-76) [cytosol] (R-HSA-8869049) N6-glycyl-L-lysine-UBB(153-228) [cytosol] (R-HSA-8869046) N6-glycyl-L-lysine-UBB(77-152) [cytosol] (R-HSA-8869047) adenylatedG152-UBB(77-152) [nucleoplasm] (R-HSA-8852094) adenylatedG228-UBB(153-228) [nucleoplasm] (R-HSA-8852104) adenylatedG76-UBB(1-76) [nucleoplasm] (R-HSA-8852101) UBB [cytosol] (R-HSA-8853516) adenylatedG76-UBB(1-76) [cytosol] (R-HSA-8852121) adenylatedG228-UBB(153-228) [cytosol] (R-HSA-8852049) adenylatedG152-UBB(77-152) [cytosol] (R-HSA-8852113) Ub-124-UBB(77-152) [endoplasmic reticulum membrane] (R-HSA-8943100) Ub-48-UBB(1-76) [endoplasmic reticulum membrane] (R-HSA-8943138) Ub-200-UBB(153-228) [endoplasmic reticulum membrane] (R-HSA-8943117) UBB(153-228) [plasma membrane] (R-HSA-3149455) UBB(1-76) [plasma membrane] (R-HSA-3149453) UBB(77-152) [plasma membrane] (R-HSA-3149463) UBB(77-152) [endosome membrane] (R-HSA-939251) UBB(1-76) [endosome membrane] (R-HSA-939240) UBB(153-228) [endosome membrane] (R-HSA-939247) UBB(153-228) [endoplasmic reticulum membrane] (R-HSA-8943098) UBB(77-152) [endoplasmic reticulum membrane] (R-HSA-8943111) UBB(1-76) [endoplasmic reticulum membrane] (R-HSA-8943078) Ub-106-UBB(77-152) [cytosol] (R-HSA-5689191) Ub-182-UBB(153-228) [cytosol] (R-HSA-5689214) Ub-29-UBB(1-76) [cytosol] (R-HSA-5689207) Ub-158-UBB(153-228) [cytosol] (R-HSA-5689099) Ub-82-UBB(77-152) [cytosol] (R-HSA-5689080) Ub-6-UBB(1-76) [cytosol] (R-HSA-5689075) Ub-33-UBB(1-76) [cytosol] (R-HSA-5689198) Ub-186-UBB(153-228) [cytosol] (R-HSA-5689146) Ub-110-UBB(77-152) [cytosol] (R-HSA-5689203) Ub-27-UBB(1-76) [cytosol] (R-HSA-5689161) Ub-104-UBB(77-152) [cytosol] (R-HSA-5689139) Ub-180-UBB(153-228) [cytosol] (R-HSA-5689138) Ub-11-UBB(1-76) [cytosol] (R-HSA-3095929) Ub-163-UBB(153-228) [cytosol] (R-HSA-3095932) Ub-87-UBB(77-152) [cytosol] (R-HSA-3095917) Ub-139-UBB(77-152) [endosome membrane] (R-HSA-939217) Ub-215-UBB(153-228) [endosome membrane] (R-HSA-939193) Ub-63-UBB(1-76) [endosome membrane] (R-HSA-939167) Ub-139-UBB(77-152) [plasma membrane] (R-HSA-939867) Ub-63-UBB(1-76) [plasma membrane] (R-HSA-939872) Ub-215-UBB(153-228) [plasma membrane] (R-HSA-939852) Ub-27-UBB(1-76) [nucleoplasm] (R-HSA-6782673) Ub-180-UBB(153-228) [nucleoplasm] (R-HSA-6782604) Ub-104-UBB(77-152) [nucleoplasm] (R-HSA-6782627) Ub-106-UBB(77-152) [nucleoplasm] (R-HSA-6782652) Ub-182-UBB(153-228) [nucleoplasm] (R-HSA-6782665) Ub-29-UBB(1-76) [nucleoplasm] (R-HSA-6782595) Ub-124-UBB(77-152) [nucleoplasm] (R-HSA-6782527) Ub-48-UBB(1-76) [nucleoplasm] (R-HSA-6782505) Ub-200-UBB(153-228) [nucleoplasm] (R-HSA-6782478) Ub-11-UBB(1-76) [nucleoplasm] (R-HSA-6782649) Ub-87-UBB(77-152) [nucleoplasm] (R-HSA-6782607) Ub-163-UBB(153-228) [nucleoplasm] (R-HSA-6782598) Ub-186-UBB(153-228) [nucleoplasm] (R-HSA-6782655) Ub-110-UBB(77-152) [nucleoplasm] (R-HSA-6782591) Ub-33-UBB(1-76) [nucleoplasm] (R-HSA-6782601) UBB(77-152) [nucleoplasm] (R-HSA-939870) UBB(1-76) [nucleoplasm] (R-HSA-939847) UBB(153-228) [nucleoplasm] (R-HSA-939854) Ub-48-UBB(1-76) [nucleoplasm] (R-HSA-5683040) Ub-124-UBB(77-152) [nucleoplasm] (R-HSA-5683036) Ub-200-UBB(153-228) [nucleoplasm] (R-HSA-5683038) Ub-139-UBB(77-152) [nucleoplasm] (R-HSA-6782488) Ub-63-UBB(1-76) [nucleoplasm] (R-HSA-6782489) Ub-215-UBB(153-228) [nucleoplasm] (R-HSA-6782475) Ub-82-UBB(77-152) [nucleoplasm] (R-HSA-6782683) Ub-6-UBB(1-76) [nucleoplasm] (R-HSA-6782600) Ub-158-UBB(153-228) [nucleoplasm] (R-HSA-6782639) UBB(153-228) [late endosome lumen] (R-HSA-9660014) UBB(77-152) [late endosome lumen] (R-HSA-9660021) UBB(1-76) [late endosome lumen] (R-HSA-9660017) Ub-48-UBB(1-76) [cytosol] (R-HSA-939249) Ub-124-UBB(77-152) [cytosol] (R-HSA-939225) Ub-200-UBB(153-228) [cytosol] (R-HSA-939197) UBB(153-228) [cytosol] (R-HSA-939230) UBB(77-152) [cytosol] (R-HSA-939213) UBB(1-76) [cytosol] (R-HSA-939214) UBB(77-152) [lysosomal lumen] (R-HSA-9660011) UBB(1-76) [lysosomal lumen] (R-HSA-9660024) UBB(153-228) [lysosomal lumen] (R-HSA-9660025) Ub-63-UBB(1-76) [cytosol] (R-HSA-939224) Ub-215-UBB(153-228) [cytosol] (R-HSA-939168) Ub-139-UBB(77-152) [cytosol] (R-HSA-939235)	0.564	2
UniProt:Q13489 BIRC3	3	K48pUb-BIRC3 [cytosol] (R-HSA-5675478) BIRC3 [cytosol] (R-HSA-50845) K63polyUb-BIRC3 [cytosol] (R-HSA-5668478)	0.564	2
UniProt:Q15560 TCEA2			0.556	3
UniProt:Q7Z417 NUFP2			0.556	3
UniProt:B2R8Y4 B2R8Y4			0.556	3
UniProt:Q7L945 ZNF627	1	ZNF627 [nucleoplasm] (R-HSA-2127594)	0.556	3
UniProt:Q9NQW5 PRDM7	1	PRDM7 [nucleoplasm] (R-HSA-3343767)	0.556	3
UniProt:D3DUQ6 D3DUQ6			0.556	3
UniProt:Q96CS2 HAUS1	1	HAUS1 [cytosol] (R-HSA-8855199)	0.556	3
UniProt:Q92529 SHC3	2	p-Y-SHC3 [cytosol] (R-HSA-3009043) SHC3 [cytosol] (R-HSA-3006448)	0.556	3
UniProt:P35452 HXD12			0.556	3
UniProt:Q01844 EWS			0.556	3
UniProt:Q8N0S2 SYCE1	1	SYCE1 [nucleoplasm] (R-HSA-912456)	0.556	3
UniProt:Q9H0I2 ENKD1			0.556	3
UniProt:Q99697-2 PITX2			0.556	3
UniProt:Q8IUH3-3 RBM45			0.556	3
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
UniProt:Q9BXY8 BEX2			0.556	3
UniProt:Q14119 VEZF1			0.556	3
UniProt:Q8TB45 DPTOR			0.556	3
UniProt:Q96BR6 ZNF669	1	ZNF669 [nucleoplasm] (R-HSA-2248869)	0.556	3
UniProt:P63218 GNG5	1	GNG5 [plasma membrane] (R-HSA-164383)	0.556	3
UniProt:Q5JUK2 SOLH1			0.556	3
UniProt:Q96JN0 LCOR			0.556	3
UniProt:Q5T5P2-6 KIAA1217			0.556	3
UniProt:Q07002 CDK18			0.556	3
UniProt:P10606 COX5B	1	COX5B [mitochondrial inner membrane] (R-HSA-164307)	0.556	3
UniProt:Q96GY3 LIN37	1	LIN37 [nucleoplasm] (R-HSA-389101)	0.556	3
UniProt:Q13115 DUSP4	1	DUSP4 [nucleoplasm] (R-HSA-203794)	0.556	3
UniProt:Q6PJG3 Q6PJG3			0.556	3
UniProt:P09067 HXB5			0.556	3
UniProt:Q8IUH3 RBM45			0.556	3
UniProt:P36406 TRI23			0.556	3
UniProt:O75603 GCM2			0.556	3
UniProt:O95678 KRT75	1	KRT75 [cytosol] (R-HSA-6809652)	0.556	3
UniProt:Q96KQ4 PPP1R13B	1	PPP1R13B [nucleoplasm] (R-HSA-6799775)	0.556	3
UniProt:Q8NEA6-2 GLIS3			0.556	3
UniProt:Q3SYA9 P12L1			0.556	3
UniProt:Q8TAE8 GADD45GIP1	1	GADD45GIP1 [mitochondrial matrix] (R-HSA-5368253)	0.556	3
UniProt:Q9Y2K2-7 SIK3			0.556	3
UniProt:Q24JT5 Q24JT5			0.556	3
UniProt:Q9P0T4 ZN581			0.556	3
UniProt:Q9NQL9 DMRT3			0.556	3
UniProt:Q96MK2 RIPR3			0.556	3
UniProt:Q9BV90 SNRNP25	1	SNRNP25 [nucleoplasm] (R-HSA-6787847)	0.556	3
UniProt:Q14D33 RTP5	1	RTP5 [plasma membrane] (R-HSA-8939451)	0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:Q5JS98 Q5JS98			0.556	3
UniProt:A0A087WSW0 A0A087WSW0			0.556	3
UniProt:Q5T619 ZN648			0.556	3
UniProt:Q9NP98 MYOZ1			0.556	3
UniProt:Q53FD0 ZC21C			0.556	3
UniProt:Q494U1-3 PLEKHN1			0.556	3
UniProt:Q9ULM2 ZNF490	1	ZNF490 [nucleoplasm] (R-HSA-1247870)	0.556	3
UniProt:A0A0S2Z5X4 A0A0S2Z5X4			0.556	3
UniProt:Q9NX63 CHCHD3	3	CHCHD3 [mitochondrial intermembrane space] (R-HSA-8874907) CHCHD3 (MIC19) [mitochondrial inner membrane] (R-HSA-8949583) 4xHC-CHCHD3 [mitochondrial intermembrane space] (R-HSA-8874910)	0.556	3
UniProt:Q8IYE0-2 CCDC146			0.556	3
UniProt:Q8N5N6 Q8N5N6			0.556	3
IntAct:EBI-22317744 CCSB ORF ID			0.556	3
UniProt:Q9UJF2 RASAL2	1	RASAL2 [cytosol] (R-HSA-5658224)	0.556	3
UniProt:Q9HAK2 COE2			0.556	3
UniProt:Q8N715 CC185			0.556	3
UniProt:P17027 ZNF23	1	ZNF23 [nucleoplasm] (R-HSA-1027395)	0.556	3
UniProt:Q7L591-3 DOK3			0.556	3
UniProt:Q96JN0-2 LCOR			0.556	3
UniProt:Q0D2K3 RIPP1			0.556	3
UniProt:Q8WWW0 RASF5			0.556	3
UniProt:Q96MY7 F161B			0.556	3
UniProt:O95759 TBCD8			0.556	3
UniProt:Q8TAU3 ZNF417	1	ZNF417 [nucleoplasm] (R-HSA-1247539)	0.556	3
UniProt:Q8TES7-6 FBF1			0.556	3
UniProt:Q15040 JOSD1	1	JOSD1 [cytosol] (R-HSA-5688784)	0.556	3
UniProt:Q9H596 DUS21			0.556	3
UniProt:Q6UXK5 LRRN1			0.556	3
UniProt:Q9BSW2 CRACR2A	2	CRACR2A [specific granule lumen] (R-HSA-6799553) CRACR2A [extracellular region] (R-HSA-6806289)	0.556	3
UniProt:Q9P2K3-2 RCOR3			0.556	3
UniProt:Q9BQ24 ZFY21			0.556	3
UniProt:Q8IVT4 Q8IVT4			0.556	3
UniProt:Q53TS8 C2CD6			0.556	3
UniProt:P12035 KRT3	1	KRT3 [cytosol] (R-HSA-6809628)	0.556	3
UniProt:Q7Z5V6-2 PPP1R32			0.556	3
UniProt:Q96LM5 CD045			0.556	3
UniProt:Q03989 ARI5A			0.556	3
UniProt:Q6BCY4 CYB5R2	1	CYB5R2 [endoplasmic reticulum membrane] (R-HSA-6806861)	0.556	3
UniProt:A0AVN2 A0AVN2			0.556	3
UniProt:Q7Z3I7 ZN572			0.556	6
UniProt:Q9NQB0-10 TCF7L2			0.556	3
UniProt:Q9HBE1-4 PATZ1			0.556	3
UniProt:O14964 HGS	2	HGS [phagocytic vesicle lumen] (R-HSA-9635660) HGS [cytosol] (R-HSA-182954)	0.556	3
UniProt:Q8NEA9 GMCL2			0.556	3
UniProt:Q08AG5 ZN844			0.556	3
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.556	3
UniProt:Q9Y5U2 TSSC4			0.556	3
UniProt:Q96HB5 CC120			0.556	3
UniProt:P52272 HNRNPM	1	HNRNPM [nucleoplasm] (R-HSA-71949)	0.556	3
UniProt:Q5T0L3 SPT46			0.556	3
UniProt:Q8IXW0 LMTD2			0.556	3
UniProt:Q9UII6 DS13B			0.556	3
UniProt:Q5W150 YT011			0.556	3
UniProt:Q9NRE2 TSH2			0.556	3
UniProt:Q9P2K5-2 MYEF2			0.556	3
UniProt:Q7Z6R9 TFAP2D	1	TFAP2D [nucleoplasm] (R-HSA-5626817)	0.556	3
UniProt:Q15915 ZIC1			0.556	3
UniProt:Q96NU1 SAM11			0.556	3
UniProt:Q8IWZ5 TRI42			0.556	3
UniProt:Q9Y260 Q9Y260			0.556	3
UniProt:Q9NUL5 SHFL			0.556	3
UniProt:Q68DK2-5 ZFYVE26			0.556	3
UniProt:O95935 TBX18			0.556	3
UniProt:Q96D16 Q96D16			0.556	3
UniProt:Q96AL5 Q96AL5			0.556	3
UniProt:Q08043 ACTN3	1	ACTN3 [cytosol] (R-HSA-390565)	0.556	3
UniProt:Q5TAP6 UTP14C	1	UTP14C [nucleoplasm] (R-HSA-8867818)	0.556	3
UniProt:Q9Y2V2 CHSP1			0.556	3
UniProt:P23769 GATA2	1	GATA2 [nucleoplasm] (R-HSA-996735)	0.556	3
UniProt:Q02040-3 AKAP17A			0.556	3
UniProt:Q08499 PDE4D	1	PDE4D [cytosol] (R-HSA-52389)	0.556	3
UniProt:P43243 MATR3			0.556	3
UniProt:Q6ZS27-3 ZNF662			0.556	3
UniProt:Q49AN0 CRY2	4	p-S-CRY2 [nucleoplasm] (R-HSA-400328) p-S-CRY2 [cytosol] (R-HSA-400305) CRY2 [cytosol] (R-HSA-400255) Ub-p-S-CRY2 [nucleoplasm] (R-HSA-517935)	0.556	3
UniProt:A6NI15 MSGN1			0.556	3
UniProt:Q9NWL9 Q9NWL9			0.556	3
UniProt:Q9NVL1 F86C1			0.556	3
UniProt:P31273 HXC8			0.556	3
UniProt:Q9NVL8 CC198			0.556	3
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:Q6ZT89 S2548			0.556	3
UniProt:Q96GV9 MACIR			0.556	3
UniProt:P28676 GCA	2	GCA [azurophil granule lumen] (R-HSA-6799167) GCA [extracellular region] (R-HSA-6806174)	0.556	3
UniProt:Q96IZ5 RBM41			0.556	3
UniProt:P78337 PITX1			0.556	3
UniProt:Q9NUL5-4 SHFL			0.556	3
UniProt:Q2WGJ6 KLH38			0.556	3
UniProt:P38936 CDKN1A	5	p-Y77-CDKN1A [cytosol] (R-HSA-8942601) p-T145-CDKN1A [cytosol] (R-HSA-198614) CDKN1A [cytosol] (R-HSA-182512) p-S130-CDKN1A [nucleoplasm] (R-HSA-187857) CDKN1A [nucleoplasm] (R-HSA-182585)	0.556	3
UniProt:A1L4H1 SSC5D	1	SSC5D [extracellular region] (R-HSA-8878615)	0.556	3
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.556	3
UniProt:Q16512 PKN1	3	PKN1 [cytosol] (R-HSA-5623613) p-T774-PKN1 [cytosol] (R-HSA-5623651) p-T774-PKN1 [nucleoplasm] (R-HSA-5625721)	0.556	3
UniProt:O75604 USP2	2	USP2 [cytosol] (R-HSA-5212661) USP2 [nucleoplasm] (R-HSA-5689946)	0.556	3
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.556	3
UniProt:Q99728 BARD1	13	BARD1 C71Y [nucleoplasm] (R-HSA-9700808) BARD1 G623E [nucleoplasm] (R-HSA-9699135) BARD1 C53W [nucleoplasm] (R-HSA-9700807) BARD1 G623W [nucleoplasm] (R-HSA-9699148) BARD1 W34R [nucleoplasm] (R-HSA-9699166) p-T714,T734-BARD1 [nucleoplasm] (R-HSA-5659846) K6PolyUb,p-T714,T734-BARD1 [nucleoplasm] (R-HSA-9707286) K6PolyUb-BARD1 [nucleoplasm] (R-HSA-9701024) BARD1 [nucleoplasm] (R-HSA-5659775) BARD1 C83G [nucleoplasm] (R-HSA-9699139) BARD1 C50G [nucleoplasm] (R-HSA-9699137) BARD1 L44R [nucleoplasm] (R-HSA-9699126) BARD1 H68Y [nucleoplasm] (R-HSA-9699151)	0.556	3
UniProt:Q08426 EHHADH	2	EHHADH [cytosol] (R-HSA-9033147) EHHADH [peroxisomal matrix] (R-HSA-400155)	0.556	3
UniProt:Q9BTA9 WAC	1	WAC [nucleoplasm] (R-HSA-8942150)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:P12236 SLC25A6	2	SLC25A6 [mitochondrial inner membrane] (R-HSA-49745) SLC25A6 [mitochondrial intermembrane space] (R-HSA-1955374)	0.556	3
UniProt:Q92844 TANK	2	TANK [cytosol] (R-HSA-933407) K63polyUb-TANK [cytosol] (R-HSA-5362480)	0.547	2
UniProt:P69974 YSCK			0.508	2
UniProt:Q14161 GIT2			0.508	2
UniProt:A0A024R4Q5 A0A024R4Q5			0.488	4
UniProt:Q9H190 SDCB2			0.488	2
UniProt:O75934 BCAS2	1	BCAS2 [nucleoplasm] (R-HSA-5420902)	0.488	2
UniProt:Q96CG3 TIFA	2	p-T9-TIFA [cytosol] (R-HSA-9645512) TIFA [cytosol] (R-HSA-451582)	0.488	2
UniProt:Q96HA8 NTAQ1			0.488	2
UniProt:Q9Y2K1 ZBTB1			0.488	2
UniProt:O43741 PRKAB2	3	PRKAB2 [nucleoplasm] (R-HSA-164096) PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [cytosol] (R-HSA-200411)	0.488	2
UniProt:O75791 GRAP2	1	GRAP2 [cytosol] (R-HSA-202367)	0.488	2
UniProt:P15976-2 GATA1			0.488	3
UniProt:Q9NR46 SHLB2			0.488	2
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.488	2
UniProt:Q8N448 LNX2			0.488	2

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