Reactome | TRAF1 [cytosol]

TRAF1 [cytosol]

Stable Identifier

R-HSA-5634163

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

TNF receptor associated factor 1, Epstein-Barr virus-induced protein 6, EBI6

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13077 TRAF1

Gene Names

TRAF1, EBI6

Chain

chain:1-416

Reference Genes

BioGPS Gene:7185 TRAF1

COSMIC (genes):TRAF1 TRAF1

CTD Gene:7185 TRAF1

dbSNP Gene:7185 TRAF1

ENSEMBL:ENSG00000056558 TRAF1

HGNC:12031 TRAF1

KEGG Gene (Homo sapiens):7185 TRAF1

Monarch:7185 TRAF1

NCBI Gene:7185 TRAF1

OMIM:601711 TRAF1

UCSC:Q13077 TRAF1

Reference Transcript

Other Identifiers

0002630041

11721587_at

11721588_at

11721589_a_at

17097941

1852

205599_at

235116_at

3223741

3223742

3223743

3223744

3223745

3223748

3223749

3223750

3223753

3223754

3223759

3223764

3223765

3223767

3223770

3223771

3M0D

5E1T

5H10

7185

74382_g_at

74384_at

76878_at

8163825

848_at

849_g_at

90942_at

9593

A_23_P216970

A_24_P89891

AAA62309

AAH24145

AAV38215

AC006430

AK090468

AK295959

AK315476

AL832989

BAC03449

BAG37860

BAG58739

BC024145

BT019408

CAB009593

CAH56343

CCDS55335

CCDS6825

CH471090

EAW87479

ENSG00000056558

ENSP00000362994

ENSP00000438583

ENSP00000443183

ENST00000373887

ENST00000373887.7

ENST00000540010

ENST00000540010.1

ENST00000546084

ENST00000546084.5

EntrezGene:7185

EntrezGene:TRAF1

g5032192_3p_at

GE58373

GO:0003674

GO:0005164

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005829

GO:0005886

GO:0006464

GO:0006915

GO:0006950

GO:0007165

GO:0008150

GO:0008219

GO:0008270

GO:0009058

GO:0009898

GO:0010803

GO:0019899

GO:0022607

GO:0031625

GO:0031996

GO:0032991

GO:0033209

GO:0034641

GO:0035631

GO:0042802

GO:0042981

GO:0043122

GO:0043167

GO:0046330

GO:0051092

GO:0065003

GO:0070534

GO:2001236

HGNC:12031

HPA001852

Hs.129024.0.A1_3p_at

ILMN_1698218

ILMN_2171789

IPR002083

IPR008974

IPR012227

IPR027136

IPR032070

IPR037306

MIM:601711

NM_001190945

NM_001190947

NM_005658

NP_001177874

NP_001177876

NP_005649

PF16673

PH_hs_0032218

SM00061

TC09001541.hg

TRAF1

TRAF1-201

TRAF1-202

TRAF1-203

U19261

U19261_at

UPI0000001079

UPI00017A7143

Participant Of

input

hasComponent

TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane]

This entity regulates

Positively

TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2)

Other forms of this molecule

TRAF1(1-163) [cytosol]

TRAF1(164-416) [cytosol]

Inferred To

kbtbd3 [cytosol] (Xenopus tropicalis)

TRAF1 [cytosol] (Bos taurus)

TRAF1 [cytosol] (Canis familiaris)

TRAF1 [cytosol] (Dictyostelium discoideum)

TRAF1 [cytosol] (Gallus gallus)

TRAF1 [cytosol] (Plasmodium falciparum)

TRAF1 [cytosol] (Sus scrofa)

Traf1 [cytosol] (Mus musculus)

Traf1 [cytosol] (Rattus norvegicus)

Homologues of TRAF1 [cytosol] (Dictyostelium discoideum)

traf1 [cytosol] (Danio rerio)

Cross References

RefSeq

NP_001177874.1, NP_001177876.1, NP_005649.1

OpenTargets

ENSG00000056558

HPA

ENSG00000056558-TRAF1

GeneCards

Q13077

Ensembl

ENSP00000438583, ENST00000540010, ENSG00000056558, ENST00000546084, ENSP00000362994, ENSP00000443183, ENST00000373887

PRO

Q13077

PDB

5H10, 3M0D, 5E1T

Interactors (214)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y4K3 TRAF6	8	TRAF6 [cytosol] (R-HSA-166366) K48polyUb-TRAF6 [cytosol] (R-HSA-6783233) K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227) TRAF6 [plasma membrane] (R-HSA-936955) TRAF6 [endosome membrane] (R-HSA-450272) PolyUb-TRAF6 [cytosol] (R-HSA-6782845)	0.911	17
UniProt:Q12933 TRAF2	5	K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.855	11
UniProt:Q9BVL2 NUP58			0.841	9
UniProt:Q15555 MARE2			0.841	9
UniProt:Q13546 RIPK1	9	PolyUb-RIPK1 [cytosol] (R-HSA-6783197) K48polyUb-RIPK1 [cytosol] (R-HSA-6783308) K63pUb-K377-RIP1 [cytosol] (R-HSA-5212672) RIPK1(1-324) [cytosol] (R-HSA-5212664) p-S-RIPK1 [cytosol] (R-HSA-5218872) K63polyUb-RIPK1 [cytosol] (R-HSA-937021) RIPK1 [endosome membrane] (R-HSA-450326) RIPK1(325-671) [cytosol] (R-HSA-5212671) RIPK1 [cytosol] (R-HSA-168651)	0.798	8
UniProt:Q9BWG6 SCNM1			0.795	8
UniProt:Q6PF18 MORN3			0.795	8
UniProt:P56279 TCL1A			0.795	8
UniProt:Q13077 TRAF1	3	TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1 [cytosol] (R-HSA-5634163) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.785	5
UniProt:P20618 PSMB1	5	PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) PSMB1 [nucleoplasm] (R-HSA-174347) PSMB1 [cytosol] (R-HSA-68738)	0.781	7
UniProt:Q9H8Y8 GORASP2	2	p-T222,T225-GORASP2 [Golgi membrane] (R-HSA-2422965) GORASP2 [Golgi membrane] (R-HSA-2422385)	0.781	7
UniProt:Q9H7H0 MET17			0.781	7
UniProt:Q8IYI8 ZNF440	1	ZNF440 [nucleoplasm] (R-HSA-1247548)	0.781	7
UniProt:Q8TBZ5 ZN502			0.781	7
UniProt:Q96KM6 Z512B			0.781	7
UniProt:Q13490 BIRC2	5	K48pUb-BIRC2 [cytosol] (R-HSA-5675479) K63polyUb-BIRC2 [cytosol] (R-HSA-5668512) BIRC2(1-372) [cytosol] (R-HSA-202913) BIRC2(373-618) [cytosol] (R-HSA-202931) BIRC2 [cytosol] (R-HSA-50847)	0.738	5
UniProt:P42772 CDKN2B	1	CDKN2B [cytosol] (R-HSA-182586)	0.735	7
UniProt:Q15561 TEAD4	1	TEAD4 [nucleoplasm] (R-HSA-2032780)	0.718	6
UniProt:Q8TD31-3 CCHCR1			0.718	6
UniProt:Q8TAB5 CA216			0.718	6
UniProt:P55040 GEM			0.718	6
UniProt:Q96SQ5 ZNF587	1	ZNF587 [nucleoplasm] (R-HSA-2127565)	0.718	6
UniProt:P17024 ZNF20	1	ZNF20 [nucleoplasm] (R-HSA-975024)	0.718	6
UniProt:Q9BT49 THAP7			0.718	6
UniProt:Q99618 CDCA3			0.718	6
UniProt:Q15973 ZNF124	1	ZNF124 [nucleoplasm] (R-HSA-975017)	0.718	6
UniProt:Q9NQ94 A1CF	1	A1CF [nucleoplasm] (R-HSA-3211440)	0.718	6
UniProt:Q969H6 POP5	1	POP5 [nucleoplasm] (R-HSA-5696783)	0.718	6
UniProt:Q8IYX3 CC116			0.718	6
UniProt:Q8TBZ8 ZNF564	1	ZNF564 [nucleoplasm] (R-HSA-1973885)	0.718	6
UniProt:Q2TAL8 QRIC1			0.718	6
UniProt:Q01664 TFAP4			0.718	6
UniProt:Q9NX04 CA109			0.718	6
UniProt:Q9NZD8 SPG21			0.718	6
UniProt:P00540 MOS			0.718	6
UniProt:Q13188 STK3	4	p-T180-STK3(1-322) [cytosol] (R-HSA-2028696) STK3(1-491) [cytosol] (R-HSA-2028280) p-T180-STK3(1-491) [cytosol] (R-HSA-2028274) STK3(323-491) [cytosol] (R-HSA-2028684)	0.718	6
UniProt:Q9UBP5 HEY2	1	HEY2 [nucleoplasm] (R-HSA-1606745)	0.718	6
UniProt:Q7RTU3 OLIG3			0.718	6
UniProt:O15519 CFLAR	1	CFLAR(1-376) [cytosol] (R-HSA-51925)	0.718	6
UniProt:Q05516 ZBTB16	1	ZBTB16 [cytosol] (R-HSA-976047)	0.696	5
UniProt:Q08117-2 TLE5			0.696	6
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.696	5
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.696	7
UniProt:Q96EJ4 Q96EJ4			0.696	5
UniProt:P15408 FOSL2			0.696	5
UniProt:Q3B820 F161A			0.696	5
UniProt:P41182 BCL6	1	BCL6 [nucleoplasm] (R-HSA-5223066)	0.696	5
UniProt:Q13011 ECH1	2	ECH1(1-328) [cytosol] (R-HSA-9033152) ECH1(1-328) [peroxisomal matrix] (R-HSA-9033140)	0.666	4
UniProt:Q96BD5 PHF21A	1	PHF21A [nucleoplasm] (R-HSA-996754)	0.666	4
UniProt:Q8WXI9 GATAD2B	1	GATAD2B [nucleoplasm] (R-HSA-3702079)	0.666	4
UniProt:O76041 NEBL			0.666	4
UniProt:Q494U1 PKHN1			0.666	4
UniProt:Q96HB5-4 CCDC120			0.666	4
UniProt:Q7L591 DOK3	3	DOK3 [plasma membrane] (R-HSA-6801572) DOK3 [secretory granule membrane] (R-HSA-6801402) DOK3 [ficolin-1-rich granule membrane] (R-HSA-6801409)	0.666	4
UniProt:P09022 Hoxa1	1	Hoxa1 [nucleoplasm] (R-MMU-5617924)	0.592	4
UniProt:P0CG47 UBB	112	UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-110-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-186-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-182-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070) Ub-106-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783103) Ub-27-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783038) Ub-180-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783114) Ub-104-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783149) N6-glycyl-L-lysine-UBB(1-76) [cytosol] (R-HSA-8869049) N6-glycyl-L-lysine-UBB(153-228) [cytosol] (R-HSA-8869046) N6-glycyl-L-lysine-UBB(77-152) [cytosol] (R-HSA-8869047) Ub-106-UBB(77-152) [cytosol] (R-HSA-5689191) Ub-182-UBB(153-228) [cytosol] (R-HSA-5689214) Ub-29-UBB(1-76) [cytosol] (R-HSA-5689207) Ub-158-UBB(153-228) [cytosol] (R-HSA-5689099) Ub-82-UBB(77-152) [cytosol] (R-HSA-5689080) Ub-6-UBB(1-76) [cytosol] (R-HSA-5689075) Ub-33-UBB(1-76) [cytosol] (R-HSA-5689198) Ub-186-UBB(153-228) [cytosol] (R-HSA-5689146) Ub-110-UBB(77-152) [cytosol] (R-HSA-5689203) adenylatedG152-UBB(77-152) [nucleoplasm] (R-HSA-8852094) adenylatedG228-UBB(153-228) [nucleoplasm] (R-HSA-8852104) adenylatedG76-UBB(1-76) [nucleoplasm] (R-HSA-8852101) UBB [cytosol] (R-HSA-8853516) adenylatedG76-UBB(1-76) [cytosol] (R-HSA-8852121) adenylatedG228-UBB(153-228) [cytosol] (R-HSA-8852049) adenylatedG152-UBB(77-152) [cytosol] (R-HSA-8852113) Ub-124-UBB(77-152) [endoplasmic reticulum membrane] (R-HSA-8943100) Ub-48-UBB(1-76) [endoplasmic reticulum membrane] (R-HSA-8943138) Ub-200-UBB(153-228) [endoplasmic reticulum membrane] (R-HSA-8943117) UBB(153-228) [endoplasmic reticulum membrane] (R-HSA-8943098) UBB(77-152) [endoplasmic reticulum membrane] (R-HSA-8943111) UBB(1-76) [endoplasmic reticulum membrane] (R-HSA-8943078) UBB(153-228) [plasma membrane] (R-HSA-3149455) UBB(1-76) [plasma membrane] (R-HSA-3149453) UBB(77-152) [plasma membrane] (R-HSA-3149463) UBB(77-152) [endosome membrane] (R-HSA-939251) UBB(1-76) [endosome membrane] (R-HSA-939240) UBB(153-228) [endosome membrane] (R-HSA-939247) Ub-27-UBB(1-76) [cytosol] (R-HSA-5689161) Ub-104-UBB(77-152) [cytosol] (R-HSA-5689139) Ub-180-UBB(153-228) [cytosol] (R-HSA-5689138) Ub-11-UBB(1-76) [cytosol] (R-HSA-3095929) Ub-163-UBB(153-228) [cytosol] (R-HSA-3095932) Ub-87-UBB(77-152) [cytosol] (R-HSA-3095917) Ub-139-UBB(77-152) [endosome membrane] (R-HSA-939217) Ub-215-UBB(153-228) [endosome membrane] (R-HSA-939193) Ub-63-UBB(1-76) [endosome membrane] (R-HSA-939167) Ub-139-UBB(77-152) [plasma membrane] (R-HSA-939867) Ub-63-UBB(1-76) [plasma membrane] (R-HSA-939872) Ub-215-UBB(153-228) [plasma membrane] (R-HSA-939852) Ub-27-UBB(1-76) [nucleoplasm] (R-HSA-6782673) Ub-180-UBB(153-228) [nucleoplasm] (R-HSA-6782604) Ub-104-UBB(77-152) [nucleoplasm] (R-HSA-6782627) Ub-106-UBB(77-152) [nucleoplasm] (R-HSA-6782652) Ub-182-UBB(153-228) [nucleoplasm] (R-HSA-6782665) Ub-29-UBB(1-76) [nucleoplasm] (R-HSA-6782595) Ub-139-UBB(77-152) [nucleoplasm] (R-HSA-6782488) Ub-63-UBB(1-76) [nucleoplasm] (R-HSA-6782489) Ub-215-UBB(153-228) [nucleoplasm] (R-HSA-6782475) Ub-124-UBB(77-152) [nucleoplasm] (R-HSA-6782527) Ub-48-UBB(1-76) [nucleoplasm] (R-HSA-6782505) Ub-200-UBB(153-228) [nucleoplasm] (R-HSA-6782478) Ub-11-UBB(1-76) [nucleoplasm] (R-HSA-6782649) Ub-87-UBB(77-152) [nucleoplasm] (R-HSA-6782607) Ub-163-UBB(153-228) [nucleoplasm] (R-HSA-6782598) Ub-186-UBB(153-228) [nucleoplasm] (R-HSA-6782655) Ub-110-UBB(77-152) [nucleoplasm] (R-HSA-6782591) Ub-33-UBB(1-76) [nucleoplasm] (R-HSA-6782601) Ub-82-UBB(77-152) [nucleoplasm] (R-HSA-6782683) Ub-6-UBB(1-76) [nucleoplasm] (R-HSA-6782600) Ub-158-UBB(153-228) [nucleoplasm] (R-HSA-6782639) UBB(77-152) [nucleoplasm] (R-HSA-939870) UBB(1-76) [nucleoplasm] (R-HSA-939847) UBB(153-228) [nucleoplasm] (R-HSA-939854) Ub-48-UBB(1-76) [nucleoplasm] (R-HSA-5683040) Ub-124-UBB(77-152) [nucleoplasm] (R-HSA-5683036) Ub-200-UBB(153-228) [nucleoplasm] (R-HSA-5683038) Ub-139-UBB(77-152) [nucleoplasm] (R-HSA-5682845) Ub-215-UBB(153-228) [nucleoplasm] (R-HSA-5682844) Ub-63-UBB(1-76) [nucleoplasm] (R-HSA-5682846) UBB(153-228) [late endosome lumen] (R-HSA-9660014) UBB(77-152) [late endosome lumen] (R-HSA-9660021) UBB(1-76) [late endosome lumen] (R-HSA-9660017) Ub-48-UBB(1-76) [cytosol] (R-HSA-939249) Ub-124-UBB(77-152) [cytosol] (R-HSA-939225) Ub-200-UBB(153-228) [cytosol] (R-HSA-939197) UBB(153-228) [cytosol] (R-HSA-939230) UBB(77-152) [cytosol] (R-HSA-939213) UBB(1-76) [cytosol] (R-HSA-939214) UBB(77-152) [lysosomal lumen] (R-HSA-9660011) UBB(1-76) [lysosomal lumen] (R-HSA-9660024) UBB(153-228) [lysosomal lumen] (R-HSA-9660025) Ub-63-UBB(1-76) [cytosol] (R-HSA-939224) Ub-215-UBB(153-228) [cytosol] (R-HSA-939168) Ub-139-UBB(77-152) [cytosol] (R-HSA-939235)	0.564	2
UniProt:Q13489 BIRC3	3	K48pUb-BIRC3 [cytosol] (R-HSA-5675478) BIRC3 [cytosol] (R-HSA-50845) K63polyUb-BIRC3 [cytosol] (R-HSA-5668478)	0.564	2
UniProt:Q15560 TCEA2			0.556	3
UniProt:Q7Z417 NUFP2			0.556	3
UniProt:B2R8Y4 B2R8Y4			0.556	3
UniProt:Q7L945 ZNF627	1	ZNF627 [nucleoplasm] (R-HSA-2127594)	0.556	3
UniProt:Q9NQW5 PRDM7	1	PRDM7 [nucleoplasm] (R-HSA-3343767)	0.556	3
UniProt:D3DUQ6 D3DUQ6			0.556	3
UniProt:Q96CS2 HAUS1	1	HAUS1 [cytosol] (R-HSA-8855199)	0.556	3
UniProt:Q92529 SHC3	2	p-Y-SHC3 [cytosol] (R-HSA-3009043) SHC3 [cytosol] (R-HSA-3006448)	0.556	3
UniProt:P35452 HXD12			0.556	3
UniProt:Q99728 BARD1	2	BARD1 [nucleoplasm] (R-HSA-5659775) p-T714,T734-BARD1 [nucleoplasm] (R-HSA-5659846)	0.556	3
UniProt:Q01844 EWS			0.556	3
UniProt:Q8N0S2 SYCE1	1	SYCE1 [nucleoplasm] (R-HSA-912456)	0.556	3
UniProt:Q9BTA9 WAC	1	WAC [nucleoplasm] (R-HSA-8942150)	0.556	3
UniProt:Q9H0I2 ENKD1			0.556	3
UniProt:Q99697-2 PITX2			0.556	3
UniProt:Q8IUH3-3 RBM45			0.556	3
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
UniProt:Q9BXY8 BEX2			0.556	3
UniProt:Q14119 VEZF1			0.556	3
UniProt:Q8TB45 DPTOR			0.556	3
UniProt:Q96BR6 ZNF669	1	ZNF669 [nucleoplasm] (R-HSA-2248869)	0.556	3
UniProt:P63218 GNG5	1	GNG5 [plasma membrane] (R-HSA-164383)	0.556	3
UniProt:Q5JUK2 SOLH1			0.556	3
UniProt:Q96JN0 LCOR			0.556	3
UniProt:Q5T5P2-6 KIAA1217			0.556	3
UniProt:Q07002 CDK18			0.556	3
UniProt:P10606 COX5B	1	COX5B [mitochondrial inner membrane] (R-HSA-164307)	0.556	3
UniProt:Q96GY3 LIN37	1	LIN37 [nucleoplasm] (R-HSA-389101)	0.556	3
UniProt:Q13115 DUSP4	1	DUSP4 [nucleoplasm] (R-HSA-203794)	0.556	3
UniProt:Q6PJG3 Q6PJG3			0.556	3
UniProt:P09067 HXB5			0.556	3
UniProt:Q8IUH3 RBM45			0.556	3
UniProt:P36406 TRI23			0.556	3
UniProt:O75603 GCM2			0.556	3
UniProt:O95678 KRT75	1	KRT75 [cytosol] (R-HSA-6809652)	0.556	3
UniProt:Q96KQ4 PPP1R13B	1	PPP1R13B [nucleoplasm] (R-HSA-6799775)	0.556	3
UniProt:Q8NEA6-2 GLIS3			0.556	3
UniProt:O75604 USP2	2	USP2 [nucleoplasm] (R-HSA-5689946) USP2 [cytosol] (R-HSA-5212661)	0.556	3
UniProt:Q16512 PKN1	3	PKN1 [cytosol] (R-HSA-5623613) p-T774-PKN1 [cytosol] (R-HSA-5623651) p-T774-PKN1 [nucleoplasm] (R-HSA-5625721)	0.556	3
UniProt:Q3SYA9 P12L1			0.556	3
UniProt:Q8TAE8 GADD45GIP1	1	GADD45GIP1 [mitochondrial matrix] (R-HSA-5368253)	0.556	3
UniProt:Q9Y2K2-7 SIK3			0.556	3
UniProt:Q24JT5 Q24JT5			0.556	3
UniProt:Q9P0T4 ZN581			0.556	3
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.556	3
UniProt:P12236 SLC25A6	2	SLC25A6 [mitochondrial inner membrane] (R-HSA-49745) SLC25A6 [mitochondrial intermembrane space] (R-HSA-1955374)	0.556	3
UniProt:Q9NQL9 DMRT3			0.556	3
UniProt:Q96MK2 RIPR3			0.556	3
UniProt:Q9BV90 SNRNP25	1	SNRNP25 [nucleoplasm] (R-HSA-6787847)	0.556	3
UniProt:Q14D33 RTP5	1	RTP5 [plasma membrane] (R-HSA-8939451)	0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:Q5JS98 Q5JS98			0.556	3
UniProt:A0A087WSW0 A0A087WSW0			0.556	3
UniProt:Q5T619 ZN648			0.556	3
UniProt:Q9NP98 MYOZ1			0.556	3
UniProt:Q53FD0 ZC21C			0.556	3
UniProt:Q494U1-3 PLEKHN1			0.556	3
UniProt:Q9ULM2 ZNF490	1	ZNF490 [nucleoplasm] (R-HSA-1247870)	0.556	3
UniProt:A0A0S2Z5X4 A0A0S2Z5X4			0.556	3
UniProt:Q8IYE0-2 CCDC146			0.556	3
UniProt:Q8N5N6 Q8N5N6			0.556	3
IntAct:EBI-22317744 CCSB ORF ID			0.556	3
UniProt:Q9UJF2 RASAL2	1	RASAL2 [cytosol] (R-HSA-5658224)	0.556	3
UniProt:Q9HAK2 COE2			0.556	3
UniProt:Q8N715 CC185			0.556	3
UniProt:P17027 ZNF23	1	ZNF23 [nucleoplasm] (R-HSA-1027395)	0.556	3
UniProt:Q7L591-3 DOK3			0.556	3
UniProt:Q96JN0-2 LCOR			0.556	3
UniProt:Q0D2K3 RIPP1			0.556	3
UniProt:Q8WWW0 RASF5			0.556	3
UniProt:Q96MY7 F161B			0.556	3
UniProt:O95759 TBCD8			0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q8TAU3 ZNF417	1	ZNF417 [nucleoplasm] (R-HSA-1247539)	0.556	3
UniProt:Q8TES7-6 FBF1			0.556	3
UniProt:Q15040 JOSD1	1	JOSD1 [cytosol] (R-HSA-5688784)	0.556	3
UniProt:Q9H596 DUS21			0.556	3
UniProt:Q6UXK5 LRRN1			0.556	3
UniProt:Q9BSW2 CRACR2A	2	CRACR2A [specific granule lumen] (R-HSA-6799553) CRACR2A [extracellular region] (R-HSA-6806289)	0.556	3
UniProt:Q9P2K3-2 RCOR3			0.556	3
UniProt:Q9BQ24 ZFY21			0.556	3
UniProt:Q8IVT4 Q8IVT4			0.556	3
UniProt:Q53TS8 C2CD6			0.556	3
UniProt:P12035 KRT3	1	KRT3 [cytosol] (R-HSA-6809628)	0.556	3
UniProt:Q7Z5V6-2 PPP1R32			0.556	3
UniProt:Q96LM5 CD045			0.556	3
UniProt:Q03989 ARI5A			0.556	3
UniProt:Q6BCY4 CYB5R2	1	CYB5R2 [endoplasmic reticulum membrane] (R-HSA-6806861)	0.556	3
UniProt:A0AVN2 A0AVN2			0.556	3
UniProt:Q7Z3I7 ZN572			0.556	6
UniProt:Q9NQB0-10 TCF7L2			0.556	3
UniProt:Q9HBE1-4 PATZ1			0.556	3
UniProt:O14964 HGS	2	HGS [phagocytic vesicle lumen] (R-HSA-9635660) HGS [cytosol] (R-HSA-182954)	0.556	3
UniProt:Q8NEA9 GMCL2			0.556	3
UniProt:Q08AG5 ZN844			0.556	3
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.556	3
UniProt:Q9Y5U2 TSSC4			0.556	3
UniProt:Q96HB5 CC120			0.556	3
UniProt:P52272 HNRNPM	1	HNRNPM [nucleoplasm] (R-HSA-71949)	0.556	3
UniProt:Q5T0L3 SPT46			0.556	3
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.556	3
UniProt:Q8IXW0 LMTD2			0.556	3
UniProt:Q9UII6 DS13B			0.556	3
UniProt:Q5W150 YT011			0.556	3
UniProt:Q9NRE2 TSH2			0.556	3
UniProt:Q9P2K5-2 MYEF2			0.556	3
UniProt:Q7Z6R9 TFAP2D	1	TFAP2D [nucleoplasm] (R-HSA-5626817)	0.556	3
UniProt:Q15915 ZIC1			0.556	3
UniProt:Q96NU1 SAM11			0.556	3
UniProt:Q8IWZ5 TRI42			0.556	3
UniProt:Q9Y260 Q9Y260			0.556	3
UniProt:Q9NUL5 SHFL			0.556	3
UniProt:Q68DK2-5 ZFYVE26			0.556	3
UniProt:O95935 TBX18			0.556	3
UniProt:Q96D16 Q96D16			0.556	3
UniProt:Q96AL5 Q96AL5			0.556	3
UniProt:Q08043 ACTN3	1	ACTN3 [cytosol] (R-HSA-390565)	0.556	3
UniProt:Q5TAP6 UTP14C	1	UTP14C [nucleoplasm] (R-HSA-8867818)	0.556	3
UniProt:Q9Y2V2 CHSP1			0.556	3
UniProt:P23769 GATA2	1	GATA2 [nucleoplasm] (R-HSA-996735)	0.556	3
UniProt:Q02040-3 AKAP17A			0.556	3
UniProt:Q08499 PDE4D	1	PDE4D [cytosol] (R-HSA-52389)	0.556	3
UniProt:P43243 MATR3			0.556	3
UniProt:Q6ZS27-3 ZNF662			0.556	3
UniProt:A6NI15 MSGN1			0.556	3
UniProt:Q9NWL9 Q9NWL9			0.556	3
UniProt:Q9NVL1 FA86C			0.556	3
UniProt:P31273 HXC8			0.556	3
UniProt:Q9NVL8 CC198			0.556	3
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:Q6ZT89 S2548			0.556	3
UniProt:Q96GV9 MACIR			0.556	3
UniProt:P28676 GCA	2	GCA [azurophil granule lumen] (R-HSA-6799167) GCA [extracellular region] (R-HSA-6806174)	0.556	3
UniProt:Q96IZ5 RBM41			0.556	3
UniProt:P78337 PITX1			0.556	3
UniProt:Q9NUL5-4 SHFL			0.556	3
UniProt:Q2WGJ6 KLH38			0.556	3
UniProt:Q9NX63 CHCHD3	3	CHCHD3 [mitochondrial intermembrane space] (R-HSA-8874907) CHCHD3 (MIC19) [mitochondrial inner membrane] (R-HSA-8949583) 4xHC-CHCHD3 [mitochondrial intermembrane space] (R-HSA-8874910)	0.556	3
UniProt:A1L4H1 SSC5D	1	SSC5D [extracellular region] (R-HSA-8878615)	0.556	3
UniProt:P38936 CDKN1A	5	p-S130-CDKN1A [nucleoplasm] (R-HSA-187857) p-T145-CDKN1A [cytosol] (R-HSA-198614) p-Y77-CDKN1A [cytosol] (R-HSA-8942601) CDKN1A [cytosol] (R-HSA-182512) CDKN1A [nucleoplasm] (R-HSA-182585)	0.556	3
UniProt:Q49AN0 CRY2	4	p-S-CRY2 [nucleoplasm] (R-HSA-400328) p-S-CRY2 [cytosol] (R-HSA-400305) CRY2 [cytosol] (R-HSA-400255) Ub-p-S-CRY2 [nucleoplasm] (R-HSA-517935)	0.556	3
UniProt:Q08426 EHHADH	2	EHHADH [cytosol] (R-HSA-9033147) EHHADH [peroxisomal matrix] (R-HSA-400155)	0.556	3
UniProt:Q92844 TANK	2	TANK [cytosol] (R-HSA-933407) K63polyUb-TANK [cytosol] (R-HSA-5362480)	0.547	2
UniProt:P69974 YSCK			0.508	2
UniProt:Q14161 GIT2			0.508	2
UniProt:A0A024R4Q5 A0A024R4Q5			0.488	4
UniProt:Q9H190 SDCB2			0.488	2
UniProt:O75934 BCAS2	1	BCAS2 [nucleoplasm] (R-HSA-5420902)	0.488	2
UniProt:Q96CG3 TIFA	2	p-T9-TIFA [cytosol] (R-HSA-9645512) TIFA [cytosol] (R-HSA-451582)	0.488	2
UniProt:Q96HA8 NTAQ1			0.488	2
UniProt:Q9Y2K1 ZBTB1			0.488	2
UniProt:O43741 PRKAB2	3	PRKAB2 [nucleoplasm] (R-HSA-164096) PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [cytosol] (R-HSA-200411)	0.488	2
UniProt:P15976-2 GATA1			0.488	3
UniProt:Q9NR46 SHLB2			0.488	2
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.488	2
UniProt:Q8N448 LNX2			0.488	2
UniProt:O75791 GRAP2	1	GRAP2 [cytosol] (R-HSA-202367)	0.488	2

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