EHMT2 (KMT1C, G9A) and EHMT1 (KMT1D, GLP) are the euchromatic histone H3 lysine-10 (H3K9) mono and di-methyltransferases in mammals (Tachibana et al. 2002, Rice et al. 2003, Tachibana et al. 2005). In vivo they exist predominantly as a heteromeric complex together with WIZ, a multi-zinc finger protein, (Ueda et al. 2006) and are responsible for global H3K9 mono- and di-methylation (Shinkai & Tchibana 2011).
Tachibana, M, Sugimoto, K, Nozaki, M, Ueda, J, Ohta, T, Ohki, M, Fukuda, M, Takeda, N, Niida, H, Kato, H, Shinkai, Y
Rice, JC, Briggs, SD, Ueberheide, B, Barber, CM, Shabanowitz, J, Hunt, DF, Shinkai, Y, Allis, CD
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