SPOP [nucleoplasm]

Stable Identifier
R-HSA-5635035
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
26344095 SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression

Gan, W, Dai, X, Lunardi, A, Li, Z, Inuzuka, H, Liu, P, Varmeh, S, Zhang, J, Cheng, L, Sun, Y, Asara, JM, Beck, AH, Huang, J, Pandolfi, PP, Wei, W

Mol. Cell 2015
External Reference Information
External Reference
UniProt:O43791 SPOP
Gene Names
SPOP
Chain
chain:1-374
Reference Genes
BioGPS Gene:8405 SPOP
COSMIC (genes):SPOP SPOP
CTD Gene:8405 SPOP
dbSNP Gene:8405 SPOP
ENSEMBL:ENSG00000121067 SPOP
HGNC:11254 SPOP
KEGG Gene (Homo sapiens):8405 SPOP
Monarch:8405 SPOP
NCBI Gene:8405 SPOP
OMIM:602650 SPOP
UCSC:O43791 SPOP
Reference Transcript
Other Identifiers
0002470278
11730177_a_at
11730178_s_at
11730179_a_at
11743913_s_at
16846448
204640_s_at
208927_at
238923_at
2CR2
3761902
3761904
3761906
3761907
3761908
3761909
3761912
3761917
3761919
3761923
3761926
3761927
3761928
3761930
3761931
3761936
3761938
3761947
3761948
39423_f_at
3HQH
3HQI
3HQL
3HQM
3HSV
3HTM
3HU6
3IVB
3IVQ
3IVV
44052_at
4EOZ
4HS2
4J8Z
4O1V
6F8F
6F8G
8016562
80786_at
8405
A_23_P107257
A_24_P270890
AAH01269
AAH03385
AJ000644
AK222589
AK312691
BAD96309
BAG35570
BC001269
BC003385
CAA04199
CCDS11551
CH471109
D6RA79
D6RBR3
D6RD94
D6RDG8
D6RFL7
D6RGZ4
D6RIS7
EAW94671
EAW94672
EAW94673
EAW94674
EAW94675
ENSG00000121067
ENSP00000240327
ENSP00000377001
ENSP00000420908
ENSP00000425905
ENST00000347630
ENST00000347630.6
ENST00000393328
ENST00000393328.6
ENST00000503676
ENST00000503676.5
ENST00000504102
EntrezGene:8405
EntrezGene:SPOP
g4507182_3p_a_at
GE55133
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0006464
GO:0006511
GO:0008150
GO:0009056
GO:0016567
GO:0016607
GO:0019899
GO:0030162
GO:0031463
GO:0031625
GO:0032991
GO:0043161
GO:0043226
HGNC:11254
Hs.129951.1.S2_3p_at
Hs.151316.0.A1_3p_at
ILMN_1795404
ILMN_2397024
IPR000210
IPR002083
IPR008974
IPR011333
IPR034089
MIM:602650
NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_003563
NP_001007227
NP_001007228
NP_001007229
NP_001007230
NP_003554
PF00651
PF00917
PH_hs_0007623
SM00061
SM00225
SPOP
SPOP-201
SPOP-202
SPOP-205
SPOP-206
TC17001670.hg
UPI0000003F5C
XM_005257723
XM_005257724
XM_017025204
XM_024450995
XP_005257780
XP_005257781
XP_016880693
XP_024306763
Participant Of
hasComponent
Inferred To
Homologues of SPOP [nucleoplasm] (Caenorhabditis elegans)
Homologues of SPOP [nucleoplasm] (Dictyostelium discoideum)
Homologues of SPOP [nucleoplasm] (Drosophila melanogaster)
SPOP [nucleoplasm] (Bos taurus)
SPOP [nucleoplasm] (Caenorhabditis elegans)
SPOP [nucleoplasm] (Canis familiaris)
SPOP [nucleoplasm] (Danio rerio)
SPOP [nucleoplasm] (Dictyostelium discoideum)
SPOP [nucleoplasm] (Drosophila melanogaster)
SPOP [nucleoplasm] (Gallus gallus)
SPOP [nucleoplasm] (Mus musculus)
SPOP [nucleoplasm] (Rattus norvegicus)
SPOP [nucleoplasm] (Sus scrofa)
SPOP [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
PRO
PDB
Interactors (4)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q99836 MYD88  9 0.786 7
 UniProt:Q9UER7 DAXX  2 0.69 5
 UniProt:Q9Y6Q9 NCOA3  2 0.632 6
 UniProt:P60484 PTEN  41 0.611 4