Reactome | p-GLI1 [ciliary tip]

p-GLI1 [ciliary tip]

Stable Identifier

R-HSA-5635040

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ciliary tip

Synonyms

Zinc finger protein GLI1, GLI1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P08151 GLI1

Gene Names

GLI1, GLI

Chain

chain:1-1106

Reference Genes

COSMIC (genes):GLI1 GLI1

dbSNP Gene:2735 GLI1

ENSEMBL:ENSG00000111087 GLI1

Participates

as a member of

p-GLI1,2,3 [ciliary tip] (Homo sapiens)

Other forms of this molecule

ub-GLI1 [cytosol]

ub-pS-GLI1 [ciliary base]

pS-GLI1 [ciliary base]

GLI1 [cytosol]

2p-GLI1 [nucleoplasm]

p-GLI1 [nucleoplasm]

GLI1 [ciliary base]

GLI1 [ciliary tip]

Inferred To

phospho-p-GLI1 [ciliary tip] (Gallus gallus)

phospho-Gli1 [ciliary tip] (Mus musculus)

phospho-Gli1 [ciliary tip] (Rattus norvegicus)

phospho-gli1 [ciliary tip] (Xenopus tropicalis)

phospho-ci [ciliary tip] (Drosophila melanogaster)

phospho-GLI1 [ciliary tip] (Bos taurus)

phospho-GLI1 [ciliary tip] (Canis familiaris)

phospho-GLI1 [ciliary tip] (Sus scrofa)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UMX1 SUFU	3	SUFU [ciliary base] (R-HSA-5610424) SUFU [cytosol] (R-HSA-445455) SUFU [ciliary tip] (R-HSA-5610426)	0.968	27
UniProt:Q9QZS3-2 NUMB			0.611	4
UniProt:Q96J02 ITCH	2	Ub-C871-ITCH [cytosol] (R-HSA-8864515) ITCH [cytosol] (R-HSA-975995)	0.602	4
UniProt:Q9UMX1-2 SUFU			0.571	4
UniProt:Q96CN9 GCC1	1	GCC1 [cytosol] (R-HSA-6813877)	0.556	3
UniProt:P54646 PRKAA2	4	PRKAA2 [cytosol] (R-HSA-200405) p-T172-PRKAA2 [cytosol] (R-HSA-200417) p-T172-PRKAA2 [nucleoplasm] (R-HSA-164171) PRKAA2 [nucleoplasm] (R-HSA-163682)	0.556	3
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.556	3
UniProt:Q8IWZ5 TRI42			0.556	3
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.556	3
UniProt:P53673 CRBA4			0.556	3
UniProt:Q8NEC5 CATSPER1	1	CATSPER1 [plasma membrane] (R-HSA-2534335)	0.556	3
UniProt:P23443-2 RPS6KB1			0.544	2
UniProt:Q9NRP7 STK36			0.536	2
UniProt:P46684 ZIC1			0.524	2
UniProt:P40337 VHL	3	monoSUMO1-K159,171,196-VHL [nucleoplasm] (R-HSA-4551697) VHL [nucleoplasm] (R-HSA-1234127) VHL [cytosol] (R-HSA-391423)	0.463	2

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