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p-5Y-EGFRvIII:GRB2:GAB1:PI3K [plasma membrane]
Stable Identifier
R-HSA-5637693
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by EGFR in Cancer (Homo sapiens)
Signaling by EGFRvIII in Cancer (Homo sapiens)
Constitutive Signaling by EGFRvIII (Homo sapiens)
Binding of PI3K to complex of GRB2:GAB1 and p-EGFRvIII (Homo sapiens)
p-5Y-EGFRvIII:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII (Homo sapiens)
p-5Y-EGFRvIII:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
Participants
components
p-5Y-EGFRvIII:GRB2:GAB1 [plasma membrane]
(Homo sapiens)
PIK3CA:PIK3R1 [cytosol]
(Homo sapiens)
Participates
as an output of
Binding of PI3K to complex of GRB2:GAB1 and p-EGFRvIII (Homo sapiens)
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