CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body

Stable Identifier
R-HSA-5638009
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The distal appendage protein CEP164 interacts with RAB3IP, and in this way recruits Golgi-derived vesicles to the basal body to initiate ciliary membrane biogenesis (Schmidt et al, 2012; Westlake et al, 2011; Rohatgi and Snell, 2010). RAB3IP recruitment to the distal appendages of centrioles promotes the appropriate localization and activation of RAB8A (Nachury et al, 2007; Yoshimura et al, 2007; Westlake et al, 2011; Schmidt et al, 2012).

Participants
Participant Of
Orthologous Events