PDE6D dissociates from ARL13B:INPP5E

Stable Identifier
R-HSA-5638012
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cilium
ReviewStatus
5/5
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PDE6D dissociates from ARL13B:INPP5E
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ARL13B promotes the ciliary localization of INPP5E by interacting with it directly and displacing PDE6D from the complex (Humbert et al, 2012).
Literature References
PubMed ID Title Journal Year
23150559 ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting

Seo, S, Searby, CC, Li, Y, Pope, RM, Sheffield, VC, Humbert, MC, Weihbrecht, K

Proc. Natl. Acad. Sci. U.S.A. 2012
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Orthologous Events
PDE6D dissociates from ARL13B:INPP5E (Bos taurus)
PDE6D dissociates from ARL13B:INPP5E (Canis familiaris)
PDE6D dissociates from ARL13B:INPP5E (Gallus gallus)
PDE6D dissociates from ARL13B:INPP5E (Mus musculus)
PDE6D dissociates from ARL13B:INPP5E (Rattus norvegicus)
PDE6D dissociates from ARL13B:INPP5E (Sus scrofa)
Authored
Rothfels, K  (2014-10-30)
Reviewed
Lorentzen, E  (2014-11-10)
Goncalves, J  (2014-11-14)
Created
Rothfels, K  (2014-11-13)
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