WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27)

Stable Identifier
R-HSA-5638333
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
WHSC1 methylates lysine-28 of histone H3
Locations in the PathwayBrowser
General
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WHSC1 (KMT3G, MMSET) is able to mono-, di- and trimethylate lysine-28 (Kim et al. 2008).

Literature References
PubMed ID Title Journal Year
18172012 Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity

Kim, JY, Kee, HJ, Choe, NW, Kim, SM, Eom, GH, Baek, HJ, Kook, H, Kook, H, Seo, SB

Mol. Cell. Biol. 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
histone-lysine N-methyltransferase activity of WHSC1, WHSC1L1 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created