LIG1 and POLB dissociate from repaired dsDNA

Stable Identifier
R-HSA-5651792
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
LIG1 and POLB dissociate from repaired dsDNA
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
After the POLB-dependent long patch base excision (BER) is completed, POLB and LIG1 dissociate from repaired DNA (Ranalli et al. 2002).
Literature References
PubMed ID Title Journal Year
12200445 AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair.

Ranalli, TA, Bambara, RA, Tom, S

J Biol Chem 2002
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2014-12-04)
Reviewed
Borowiec, JA  (2014-12-22)
Created
Orlic-Milacic, M  (2014-11-24)
Cite Us!