B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac

Stable Identifier
R-HSA-5653878
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Glc + UDP-Gal => Lac + UDP
Locations in the PathwayBrowser
General
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In the Golgi membrane, the B4GALT1 subunit of the B4GALT1:LALBA (beta-1,4-galactosyltransferase 1 : alpha-lactalbumin) complex catalyzes the transfer of galactose from UDP-galactose to free glucose to form galactose and UDP (Andrews 1970; Ramakrishnan & Qasba 2001). The representation here of a stable protein complex catalyzing the transformation of small molecule substrates provides a simplified view of the true reaction mechanism (Brew and Hill 1975), but is sufficient to identify the key participating molecules and their roles.

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
lactose synthase activity of B4GALT1:LALBA [Golgi membrane]
Physical Entity
Activity
Orthologous Events
Reviewed
Created