Lactose synthesis

Stable Identifier
R-HSA-5653890
Type
Pathway
Species
Homo sapiens
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Synthesis of the disaccharide lactose takes place within the Golgi apparatus of epithelial cells of the lactating mammary gland. The synthesis itself is a single chemical reaction of free glucose and UDP-galactose to form lactose and UDP. For this reaction to occur, glucose is transported from the cytosol into the Golgi lumen, and B4GALT1 interacts with LALBA (alpha-lactalbumin) to modulate its substrate specificity (Brew and Hill 1975).

Literature References
PubMed ID Title Journal Year
806951 Lactose biosynthesis

Brew, K, Hill, RL

Rev. Physiol. Biochem. Pharmacol. 1975
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Event Information
Orthologous Events
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