p-4Y-PLCG1 dissociates from activated FGFR2

Stable Identifier
R-HSA-5654157
Type
Reaction
Species
Homo sapiens
Compartment
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Dissociation from the activated receptor quickly follows phosphorylation of PLC-gamma. Phosphorylated PLC-gamma catalyzes the hydrolysis of phosphatidylinositol(4, 5)bisphosphate to generate two second messengers, diacylglycerol and inositol (1,4,5) triphosphate.

Literature References
PubMed ID Title Journal Year
10579907 Phospholipase C-gamma as a signal-transducing element

Carpenter, G, Ji, Q

Exp Cell Res 1999
Participants
Participant Of
Orthologous Events
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