USP1:WDR48 binds monoUb:K164-PCNA

Stable Identifier
R-HSA-5655481
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
USP1:WDR48 binds monoUb:K164-PCNA
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Ubiquitin protease complex composed of deubiquitinating enzyme USP1 and its accessory factor WDR48 (UAF1) binds monoubiquitinated PCNA (MonoUb:K164-PCNA) (Huang et al. 2006).

Literature References
PubMed ID Title Journal Year
16531995 Regulation of monoubiquitinated PCNA by DUB autocleavage

Ploegh, HL, Galardy, PJ, Haas, W, Cohn, MA, Nijman, SM, Gygi, SP, Huang, TT, Bernards, R, Mirchandani, KD, D'Andrea, AD

Nat. Cell Biol. 2006
Participants
Input
Output
Participates
as an event of
Orthologous Events
USP1:WDR48 binds monoUb:K164-PCNA (Caenorhabditis elegans)
USP1:WDR48 binds monoUb:K164-PCNA (Canis familiaris)
USP1:WDR48 binds monoUb:K164-PCNA (Danio rerio)
USP1:WDR48 binds monoUb:K164-PCNA (Drosophila melanogaster)
USP1:WDR48 binds monoUb:K164-PCNA (Gallus gallus)
USP1:WDR48 binds monoUb:K164-PCNA (Mus musculus)
USP1:WDR48 binds monoUb:K164-PCNA (Rattus norvegicus)
USP1:WDR48 binds monoUb:K164-PCNA (Saccharomyces cerevisiae)
USP1:WDR48 binds monoUb:K164-PCNA (Schizosaccharomyces pombe)
USP1:WDR48 binds monoUb:K164-PCNA (Sus scrofa)
Authored
Orlic-Milacic, M  (2014-12-11)
Reviewed
Borowiec, JA  (2015-01-07)
Created
Orlic-Milacic, M  (2014-12-05)
Cite Us!