There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

Regulation of RAS by GAPs

Stable Identifier
R-HSA-5658442
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

The intrinsic GTPase activity of RAS proteins is stimulated by the GAP proteins, of which there are at least 10 in the human genome (reviewed in King et al, 2013).

Literature References
PubMed ID Title Journal Year
23443682 Nonredundant functions for Ras GTPase-activating proteins in tissue homeostasis Sci Signal 2013
Participants
Participant Of
Orthologous Events