Reactome | LRRK2 [cytosol]

LRRK2 [cytosol]

Stable Identifier

R-HSA-5661173

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Leucine-rich repeat serine/threonine-protein kinase 2 ecNumber2.7.11.1/ecNumber, LRRK2_HUMAN, PARK8

Locations in the PathwayBrowser for interactor UniProt:P05141 SLC25A5

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External Reference Information

External Reference

UniProt:Q5S007 LRRK2

Gene Names

LRRK2, PARK8

Chain

chain:1-2527

Reference Genes

BioGPS Gene:120892 LRRK2

COSMIC (genes):LRRK2 LRRK2

CTD Gene:120892 LRRK2

dbSNP Gene:120892 LRRK2

ENSEMBL:ENSG00000188906 LRRK2

HGNC:18618 LRRK2

KEGG Gene (Homo sapiens):120892 LRRK2

Monarch:120892 LRRK2

NCBI Gene:120892 LRRK2

OMIM:609007 LRRK2

UCSC:Q5S007 LRRK2

Reference Transcript

RefSeq:NM_198578.3 LRRK2

Other Identifiers

0006760053

11735294_a_at

11735295_a_at

120892

16749939

229584_at

3411329

3411330

3411332

3411333

3411335

3411336

3411337

3411341

3411343

3411344

3411345

3411346

3411347

3411348

3411349

3411350

3411351

3411354

3411355

3411356

3411357

3411358

3411359

3411360

3411361

3411362

3411363

3411364

3411365

3411366

3411368

3411369

3411371

3411372

3411373

3411374

3411376

3411377

3411379

3411380

3411381

3411383

3411385

3411386

3411389

3411391

3411392

3411394

3411396

3411397

3411398

3411399

3411402

3411404

3411405

3411407

3411408

3411411

3411413

3411414

3411415

51362_at

7954810

81790_at

A_23_P128447

A_33_P3369058

GE79036

GE798909

GE87175

GO:0000003

GO:0000139

GO:0000149

GO:0000165

GO:0000166

GO:0000186

GO:0000187

GO:0000287

GO:0000902

GO:0001933

GO:0001934

GO:0002376

GO:0003674

GO:0003779

GO:0003924

GO:0004672

GO:0004674

GO:0004708

GO:0004722

GO:0005096

GO:0005515

GO:0005524

GO:0005525

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005741

GO:0005743

GO:0005759

GO:0005764

GO:0005768

GO:0005773

GO:0005783

GO:0005789

GO:0005794

GO:0005798

GO:0005802

GO:0005829

GO:0005886

GO:0005902

GO:0006464

GO:0006468

GO:0006470

GO:0006605

GO:0006606

GO:0006810

GO:0006897

GO:0006913

GO:0006914

GO:0006950

GO:0006979

GO:0007005

GO:0007029

GO:0007030

GO:0007034

GO:0007040

GO:0007165

GO:0007267

GO:0007283

GO:0007528

GO:0007568

GO:0008017

GO:0008021

GO:0008092

GO:0008150

GO:0008219

GO:0008283

GO:0008340

GO:0009056

GO:0009058

GO:0009267

GO:0010468

GO:0010506

GO:0010508

GO:0010738

GO:0010955

GO:0010977

GO:0014041

GO:0015031

GO:0015631

GO:0016020

GO:0016192

GO:0016234

GO:0016242

GO:0016301

GO:0016310

GO:0016740

GO:0016787

GO:0016791

GO:0017048

GO:0017075

GO:0018105

GO:0018107

GO:0019722

GO:0019899

GO:0021700

GO:0021756

GO:0021772

GO:0022028

GO:0022607

GO:0030054

GO:0030154

GO:0030159

GO:0030234

GO:0030276

GO:0030424

GO:0030425

GO:0030426

GO:0030672

GO:0030674

GO:0031398

GO:0031410

GO:0031647

GO:0031966

GO:0032091

GO:0032092

GO:0032436

GO:0032473

GO:0032839

GO:0032991

GO:0034211

GO:0034260

GO:0034330

GO:0034599

GO:0034613

GO:0034641

GO:0035556

GO:0035564

GO:0035640

GO:0035641

GO:0035751

GO:0036479

GO:0039706

GO:0040011

GO:0040012

GO:0042391

GO:0042592

GO:0042802

GO:0042803

GO:0042995

GO:0043005

GO:0043025

GO:0043068

GO:0043167

GO:0043195

GO:0043204

GO:0043226

GO:0043231

GO:0043406

GO:0043547

GO:0044281

GO:0044325

GO:0044753

GO:0044754

GO:0045121

GO:0045202

GO:0046039

GO:0046777

GO:0048312

GO:0048812

GO:0048856

GO:0048870

GO:0050877

GO:0051018

GO:0051276

GO:0051604

GO:0051646

GO:0051770

GO:0051900

GO:0051966

GO:0060070

GO:0060079

GO:0060159

GO:0060161

GO:0060628

GO:0060828

GO:0061001

GO:0065003

GO:0070062

GO:0070585

GO:0070971

GO:0070973

GO:0070997

GO:0071287

GO:0071407

GO:0072593

GO:0090140

GO:0090263

GO:0090394

GO:0097487

GO:0098794

GO:0099400

GO:0140058

GO:1900244

GO:1901214

GO:1901215

GO:1901727

GO:1902236

GO:1902499

GO:1902692

GO:1902803

GO:1902823

GO:1902902

GO:1903125

GO:1903206

GO:1903215

GO:1903217

GO:1903351

GO:1903980

GO:1904469

GO:1904713

GO:1904887

GO:1905279

GO:1905289

GO:1990904

GO:1990909

GO:2000172

GO:2000300

Hs.124292.0.A1_3p_at

ILMN_1776649

ILMN_2226015

PH_hs_0022858

PH_hs_0041186

TC12000309.hg

Participant Of

input

Phosphorylated GPNMB recruits PTK6 and LRRK2 in the presence of LINC01139

hasComponent

Inferred To

LRRK2 [cytosol] (Bos taurus)

LRRK2 [cytosol] (Canis familiaris)

LRRK2 [cytosol] (Sus scrofa)

lrrk2 [cytosol] (Danio rerio)

lrrk2 [cytosol] (Xenopus tropicalis)

Lrrk2 [cytosol] (Mus musculus)

Lrrk2 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_940980.3

ZINC - World Drugs

LRRK2_HUMAN

OpenTargets

ENSG00000188906

ZINC - FDA approved

LRRK2_HUMAN

ZINC - Substances

LRRK2_HUMAN

ZINC target

Q5S007

ZINC - Biogenic

LRRK2_HUMAN

PRO

Q5S007

PDB

2ZEJ, 6DLO, 5MYC, 5MY9, 6DLP, 3D6T

ZINC - Investigational

LRRK2_HUMAN

GeneCards

Q5S007

HPA

ENSG00000188906-LRRK2

Ensembl

ENST00000298910, ENSP00000298910, ENSG00000188906

ZINC - Predictions - Purchasable

LRRK2_HUMAN

Orphanet

16415

HMDB Protein

HMDBP09455

Interactors (233)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.986	68
GTP [ChEBI:15996]	13	GTP [early endosome membrane] (R-ALL-2130170) GTP [cilium] (R-ALL-5617813) GTP [lysosomal membrane] (R-ALL-2213216) GTP [platelet dense granule lumen] (R-ALL-114625) GTP [cytoplasmic vesicle membrane] (R-ALL-1996291) GTP [ER to Golgi transport vesicle membrane] (R-ALL-983318) GTP [extracellular region] (R-ALL-114626) GTP [Golgi lumen] (R-ALL-8851242) GTP [endocytic vesicle lumen] (R-ALL-8851508) GTP [Golgi membrane] (R-ALL-1806221) GTP [mitochondrial matrix] (R-ALL-113573) GTP [nucleoplasm] (R-ALL-113571) GTP [cytosol] (R-ALL-29438)	0.976	26
UniProt:P26038 MSN	1	MSN [cytosol] (R-HSA-437350)	0.956	19
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.907	11
UniProt:O00429 DNM1L	2	DNM1L [cytosol] (R-HSA-351943) DNM1L [mitochondrial outer membrane] (R-HSA-351942)	0.878	14
UniProt:P27348 YWHAQ	1	YWHAQ [cytosol] (R-HSA-1445116)	0.862	10
UniProt:Q16543 CDC37	1	CDC37 [cytosol] (R-HSA-1221609)	0.845	8
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.823	8
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.821	26
UniProt:P11142 HSPA8	10	HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [cytosol] (R-HSA-264476)	0.813	6
UniProt:P30048 PRDX3	1	PRDX3 [mitochondrial matrix] (R-HSA-3323081)	0.796	14
UniProt:O14976 GAK	3	GAK [Golgi membrane] (R-HSA-434340) GAK [cytosol] (R-HSA-8868619) GAK [cytoplasmic vesicle membrane] (R-HSA-434203)	0.793	11
UniProt:P07900 HSP90AA1	8	HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [cytosol] (R-HSA-192864) HSP90AA1 [lysosomal lumen] (R-HSA-9622850)	0.788	7
UniProt:P08238 HSP90AB1	6	HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491) HSP90AB1 [secretory granule lumen] (R-HSA-6801477) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [nucleoplasm] (R-HSA-5082399) HSP90AB1 [lysosomal lumen] (R-HSA-9622846)	0.788	7
GDP [ChEBI:17552]	12	GDP [cytoplasmic vesicle membrane] (R-ALL-1996292) GDP [lysosomal membrane] (R-ALL-9628545) GDP [cilium] (R-ALL-5617810) GDP [platelet dense granule lumen] (R-ALL-114622) GDP [nucleoplasm] (R-ALL-111349) GDP [endocytic vesicle lumen] (R-ALL-8851528) GDP [Golgi lumen] (R-ALL-205689) GDP [extracellular region] (R-ALL-114623) GDP [endoplasmic reticulum lumen] (R-ALL-1467290) GDP [plasma membrane] (R-ALL-114549) GDP [mitochondrial matrix] (R-ALL-113525) GDP [cytosol] (R-ALL-29420)	0.786	8
UniProt:P62841 RPS15	2	RPS15 [cytosol] (R-HSA-72335) RPS15 [nucleoplasm] (R-HSA-6798706)	0.783	9
UniProt:P61020 RAB5B	7	RAB5B [plasma membrane] (R-HSA-6804984) RAB5B [secretory granule membrane] (R-HSA-6804966) RAB5B [cytosol] (R-HSA-8870412) GGC-RAB5B [cytosol] (R-HSA-8870434) GGC-RAB5B [early endosome membrane] (R-HSA-8875327) RAB5B [early endosome membrane] (R-HSA-2029080) GGC-RAB5B [clathrin-coated endocytic vesicle membrane] (R-HSA-8871126)	0.761	9
UniProt:O14966 RAB29	2	RAB29 [cytosol] (R-HSA-8873713) GGC-RAB29 [cytosol] (R-HSA-8873957)	0.761	15
UniProt:Q13637 RAB32	3	GGC-RAB32 [cytosol] (R-HSA-8873980) GGC-RAB32 [melanosome membrane] (R-HSA-8877737) RAB32 [cytosol] (R-HSA-8873696)	0.753	12
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.75	5
UniProt:P07437 TUBB	3	TUBB [azurophil granule lumen] (R-HSA-6799370) TUBB [cytosol] (R-HSA-9020816) TUBB [extracellular region] (R-HSA-380317)	0.744	6
IntAct:EBI-6312987 NICTIDE			0.73	4
UniProt:P05060 CHGB	2	CHGB [endoplasmic reticulum lumen] (R-HSA-8956734) p-CHGB [endoplasmic reticulum lumen] (R-HSA-8956928)	0.73	3
UniProt:Q04917 YWHAH	1	YWHAH [cytosol] (R-HSA-1445107)	0.723	4
UniProt:Q9UL15 BAG5	1	BAG5 [cytosol] (R-HSA-5255453)	0.718	12
UniProt:Q14155 ARHGEF7	1	ARHGEF7 [cytosol] (R-HSA-430346)	0.715	7
UniProt:Q9UNE7 STUB1	1	STUB1 [cytosol] (R-HSA-975970)	0.713	4
UniProt:P30084 ECHS1	1	ECHS1 [mitochondrial matrix] (R-HSA-54125)	0.713	4
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.713	5
UniProt:P61006 RAB8A	6	RAB8A [cytosol] (R-HSA-5623399) RAB8A [Golgi membrane] (R-HSA-2562535) GGC-RAB8A [cytosol] (R-HSA-8874063) GGC-RAB8A [trans-Golgi network membrane] (R-HSA-8876082) RAB8A [recycling endosome membrane] (R-HSA-8854145) GGC-RAB8A [cytoplasmic vesicle membrane] (R-HSA-1445093)	0.704	7
UniProt:P60866 RPS20	2	RPS20 [cytosol] (R-HSA-72349) RPS20 [nucleoplasm] (R-HSA-6798727)	0.688	4
UniProt:P61026 RAB10	5	GGC-RAB10 [cytosol] (R-HSA-8873783) GGC-RAB10 [cytoplasmic vesicle membrane] (R-HSA-8876076) RAB10 [cytosol] (R-HSA-8873669) RAB10 [plasma membrane] (R-HSA-6804816) RAB10 [secretory granule membrane] (R-HSA-6804788)	0.688	7
UniProt:Q8WUM0 NUP133	2	NUP133 [cytosol] (R-HSA-376251) NUP133 [nuclear envelope] (R-HSA-157743)	0.688	4
UniProt:Q13191 CBLB	1	CBLB [cytosol] (R-HSA-976009)	0.683	4
UniProt:P10636-8 MAPT	2	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.676	9
UniProt:Q13501 SQSTM1	2	SQSTM1 [cytosol] (R-HSA-193937) SQSTM1 [nucleoplasm] (R-HSA-210961)	0.676	18
UniProt:P04350 TUBB4A	6	TUBB4A unfolded [cytosol] (R-HSA-392778) TUBB4A folding intermediate [cytosol] (R-HSA-392789) Polyglycyl-TUBB4A [cytosol] (R-HSA-8867397) Polyglutamyl-TUBB4A [cytosol] (R-HSA-8867425) TUBB4A [cytosol] (R-HSA-190588) TUBB4A [axonemal microtubule] (R-HSA-5610435)	0.67	6
UniProt:P39053	3	Dnm1 [cytosol] (R-MMU-2213182) Dnm1 [lysosomal membrane] (R-MMU-196150) Dnm1 [plasma membrane] (R-MMU-177488)	0.669	3
UniProt:O95295 SNAPIN	2	SNAPIN [cytoplasmic vesicle membrane] (R-HSA-434204) SNAPIN [Golgi membrane] (R-HSA-434344)	0.66	5
UniProt:O75581 LRP6	8	p-S1490-LRP6 [plasma membrane] (R-HSA-206156) p-T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-205884) LRP6 [early endosome membrane] (R-HSA-5368481) p-LRP6 [early endosome membrane] (R-HSA-5368496) LRP6N [extracellular region] (R-HSA-5334021) p-2S,S1490,2T-LRP6 [plasma membrane] (R-HSA-1458894) p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-1458895) LRP6 [plasma membrane] (R-HSA-206252)	0.657	4
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.65	6
UniProt:P61983	1	Ywhag [cytosol] (R-RNO-380312)	0.65	6
UniProt:O15027 SEC16A	1	SEC16A [cytosol] (R-HSA-5685728)	0.649	8
UniProt:P49841 GSK3B	4	p-S9-GSK3B [cytosol] (R-HSA-3149577) GSK3B del304-316 [cytosol] (R-HSA-5339682) GSK3B [cytosol] (R-HSA-2997551) GSK3B [nucleoplasm] (R-HSA-2022823)	0.645	7
UniProt:P19338 NCL	1	NCL [nucleoplasm] (R-HSA-6791213)	0.643	4
UniProt:P62249 RPS16	2	RPS16 [cytosol] (R-HSA-72337) RPS16 [nucleoplasm] (R-HSA-6791196)	0.642	4
UniProt:P15880 RPS2	3	Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [nucleoplasm] (R-HSA-6790655) RPS2 [cytosol] (R-HSA-72347)	0.642	4
UniProt:P42677 RPS27	2	RPS27 [cytosol] (R-HSA-72361) RPS27 [nucleoplasm] (R-HSA-6791190)	0.642	4
UniProt:P62280 RPS11	2	RPS11 [cytosol] (R-HSA-72327) RPS11 [nucleoplasm] (R-HSA-6791212)	0.642	5
UniProt:P23396 RPS3	2	RPS3 [cytosol] (R-HSA-72369) RPS3 [nucleoplasm] (R-HSA-6798714)	0.642	4
UniProt:P26373 RPL13	1	RPL13 [cytosol] (R-HSA-72410)	0.642	4
UniProt:P62906 RPL10A	1	RPL10A [cytosol] (R-HSA-72404)	0.642	4
UniProt:P63151 PPP2R2A	2	PPP2R2A [nucleoplasm] (R-HSA-1564978) PPP2R2A [cytosol] (R-HSA-377253)	0.641	4
UniProt:O14641 DVL2	5	pp-DVL2 [cytosol] (R-HSA-3772398) DVL2 [cytosol] (R-HSA-201694) p-DVL2 [cytosol] (R-HSA-201706) p-DVL2 [clathrin-coated endocytic vesicle] (R-HSA-5138444) ub-DVL2 [cytosol] (R-HSA-4652689)	0.632	5
UniProt:Q99962 SH3GL2	4	SH3GL2 [cytosol] (R-HSA-182958) SH3GL2 [plasma membrane] (R-HSA-177495) SH3GL2 [clathrin-coated endocytic vesicle membrane] (R-HSA-2130629) SH3GL2 [Golgi membrane] (R-HSA-351189)	0.623	4
UniProt:Q9NQU5 PAK6	1	PAK6 [cytosol] (R-HSA-428454)	0.623	2
UniProt:Q8N8V4 ANS4B			0.623	2
UniProt:P02687 MBP			0.623	3
UniProt:P42679 MATK	1	MATK [cytosol] (R-HSA-1433581)	0.623	2
UniProt:Q9UKI2 CDC42EP3	2	CDC42EP3 [cytosol] (R-HSA-5692689) p-CDC42EP3 [cytosol] (R-HSA-5692659)	0.623	2
UniProt:P20700 LMNB1	8	LMNB1 [nucleoplasm] (R-HSA-264867) LMNB1 [cytosol] (R-HSA-2995384) p-S395, S405-LMNB1 [nucleoplasm] (R-HSA-5228738) p-S23, S395, S405-LMNB1 [nucleoplasm] (R-HSA-5229018) LMNB1(1-231) [nuclear envelope] (R-HSA-352244) LMNB1(232-586) [nuclear envelope] (R-HSA-352248) LMNB1(2-586) [nuclear envelope] (R-HSA-912402) p-S23,S393-LMNB1 [nucleoplasm] (R-HSA-8868341)	0.623	4
ChEBI:132484 MLI-2			0.623	2
UniProt:Q96PY6 NEK1			0.623	2
UniProt:O95816 BAG2	1	BAG2 [cytosol] (R-HSA-5255445)	0.623	3
UniProt:Q9NWM3 CUED1			0.623	2
UniProt:O55143	2	Atp2a2 [endoplasmic reticulum membrane] (R-MMU-391962) Atp2a2 [platelet dense tubular network membrane] (R-MMU-427903)	0.623	13
ChEBI:78408 GUANOSINE 5'-[BETA,GAMMA-IMIDO]TRIPHOSPHATE			0.623	5
UniProt:Q7L592 NDUFAF7	1	NDUFAF7 [mitochondrial matrix] (R-HSA-6788525)	0.623	2
UniProt:P60953 CDC42	3	CDC42 [cytosol] (R-HSA-442630) CDC42 [endoplasmic reticulum membrane] (R-HSA-5672086) CDC42 [plasma membrane] (R-HSA-449545)	0.621	3
UniProt:P46821-PRO_0000018605 MAP1B			0.611	5
UniProt:Q62848	1	Arfgap1 [cytosol] (R-RNO-200464)	0.61	7
UniProt:O60313 OPA1	3	OPA1(88-194) [mitochondrial inner membrane] (R-HSA-8867509) OPA1 [mitochondrial inner membrane] (R-HSA-8867508) OPA1(195-960) [mitochondrial inner membrane] (R-HSA-8867513)	0.602	5
UniProt:P55060 XPO2			0.597	4
UniProt:O00231 PSMD11	5	PSMD11 [extracellular region] (R-HSA-6806441) PSMD11 [ficolin-1-rich granule lumen] (R-HSA-6800436) PSMD11 [secretory granule lumen] (R-HSA-6800943) PSMD11 [nucleoplasm] (R-HSA-174327) PSMD11 [cytosol] (R-HSA-68790)	0.597	4
UniProt:P62269 RPS18	2	RPS18 [cytosol] (R-HSA-72341) RPS18 [nucleoplasm] (R-HSA-6798701)	0.59	3
UniProt:Q9Y6A4 CFA20			0.59	3
UniProt:Q6P3X3 TTC27			0.59	3
UniProt:Q99961 SH3GL1	1	SH3GL1 [cytosol] (R-HSA-8867732)	0.59	3
UniProt:O95218 ZRAB2			0.59	2
UniProt:Q12972 PP1R8			0.59	3
UniProt:Q53GS9 USP39	1	USP39 [nucleoplasm] (R-HSA-6806793)	0.59	3
UniProt:P49406 MRPL19	1	MRPL19 [mitochondrial inner membrane] (R-HSA-5368215)	0.59	3
UniProt:Q4G0J3 LARP7			0.59	3
UniProt:P62277 RPS13	2	RPS13 [cytosol] (R-HSA-72331) RPS13 [nucleoplasm] (R-HSA-6791198)	0.59	3
UniProt:P17612 PRKACA	3	PRKACA [cytosol] (R-HSA-57844) PRKACA [ciliary base] (R-HSA-5610402) PRKACA [nucleoplasm] (R-HSA-111936)	0.59	6
UniProt:P49207 RPL34	1	RPL34 [cytosol] (R-HSA-72458)	0.59	3
UniProt:O43865 AHCYL1	1	AHCYL1 [endoplasmic reticulum membrane] (R-HSA-5215973)	0.59	3
UniProt:P62888 RPL30	1	RPL30 [cytosol] (R-HSA-72452)	0.59	3
UniProt:Q9BQ70 TCF25			0.59	3
UniProt:Q9H0U4 RAB1B	8	GGC-RAB1B [transport vesicle membrane] (R-HSA-8877470) RAB1B [endoplasmic reticulum membrane] (R-HSA-6810977) GGC-RAB1B [cytosol] (R-HSA-8870426) RAB1B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-6807768) RAB1B [transport vesicle] (R-HSA-6808799) RAB1B [cytosol] (R-HSA-5685727) RAB1B [Golgi membrane] (R-HSA-2422381) p-T191-RAB1B [Golgi membrane] (R-HSA-2422374)	0.59	5
UniProt:Q71RC2 LARP4			0.59	3
UniProt:P46734 MAP2K3	3	p-S189,T193-MAP2K3 [cytosol] (R-HSA-167955) MAP2K3 [cytosol] (R-HSA-168051) p-S189,T193-MAP2K3 [nucleoplasm] (R-HSA-450229)	0.589	5
UniProt:Q38SD2 LRRK1			0.589	5
UniProt:P41220 RGS2	1	RGS2 [plasma membrane] (R-HSA-939787)	0.571	6
UniProt:Q05639 EEF1A2	1	EEF1A2 [cytosol] (R-HSA-3907261)	0.564	3
UniProt:Q9UKV8 AGO2	2	AGO2 [cytosol] (R-HSA-209723) EIF2C2 [nucleoplasm] (R-HSA-5578701)	0.564	3
UniProt:P05141 SLC25A5	1	SLC25A5 [mitochondrial inner membrane] (R-HSA-49743)	0.564	2
UniProt:P12236 SLC25A6	2	SLC25A6 [mitochondrial inner membrane] (R-HSA-49745) SLC25A6 [mitochondrial intermembrane space] (R-HSA-1955374)	0.564	2
UniProt:P12235 SLC25A4	3	SLC25A4 [cytosol] (R-HSA-1267975) SLC25A4 [mitochondrial intermembrane space] (R-HSA-1267984) SLC25A4 [mitochondrial inner membrane] (R-HSA-49741)	0.564	2
UniProt:P21796 VDAC1	4	PolyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-6783079) VDAC1 [mitochondrial intermembrane space] (R-HSA-1267960) K48polyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-5205624) VDAC1 [mitochondrial outer membrane] (R-HSA-1267988)	0.564	3
UniProt:Q03252 LMNB2			0.564	3
UniProt:P31749 AKT1	13	p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308-AKT1 [cytosol] (R-HSA-198634) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) AKT1 [cytosol] (R-HSA-58252) AKT1 [plasma membrane] (R-HSA-199416) p-S473-AKT1 [plasma membrane] (R-HSA-377265) p-T308,S473-AKT1 [cytosol] (R-HSA-198356)	0.558	6
UniProt:Q13469 NFATC2	4	p-S243-NFATC2 [nucleoplasm] (R-HSA-2025894) NFATC2 [nucleoplasm] (R-HSA-3791114) p-S243-NFATC2 [cytosol] (R-HSA-2685626) p-14S-NFATC2 [cytosol] (R-HSA-2025848)	0.558	3
ChEBI:78374 GPPNHP			0.558	2
UniProt:P57729 RAB38	3	GGC-RAB38 [cytosol] (R-HSA-8873999) GGC-RAB38 [melanosome membrane] (R-HSA-8877740) RAB38 [cytosol] (R-HSA-8873711)	0.558	4
UniProt:P37840 SNCA	4	SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.556	6
UniProt:Q8NHS9 SPT22			0.556	3
UniProt:P60896 SEM1	2	SHFM1 [cytosol] (R-HSA-8866674) SHFM1 [nucleoplasm] (R-HSA-8866665)	0.556	3
UniProt:P63000 RAC1	6	RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802) RAC1 [secretory granule membrane] (R-HSA-6804770) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [cytosol] (R-HSA-442615) RAC1 [plasma membrane] (R-HSA-351141)	0.556	5
UniProt:P48730-2 CSNK1D			0.556	3
IntAct:EBI-25831191 CCSB			0.556	3
UniProt:Q9BUL9 RPP25	1	RPP25 [nucleoplasm] (R-HSA-5696782)	0.556	3
UniProt:Q8N6T3 ARFGAP1	1	ARFGAP1 [cytosol] (R-HSA-200464)	0.554	2
UniProt:P68371 TUBB4B	8	TUBB4B unfolded [cytosol] (R-HSA-392779) TUBB4B folding intermediate [cytosol] (R-HSA-392788) TUBB4B [cytosol] (R-HSA-191702) TUBB4B [azurophil granule lumen] (R-HSA-6799347) TUBB4B [extracellular region] (R-HSA-6806178) TUBB4B [axonemal microtubule] (R-HSA-5610441) Polyglutamyl-TUBB4B [cytosol] (R-HSA-8867427) Polyglycyl-TUBB4B [cytosol] (R-HSA-8867452)	0.547	3
UniProt:Q9BUF5 TUBB6	6	TUBB6 unfolded [cytosol] (R-HSA-392780) TUBB6 folding intermediate [cytosol] (R-HSA-392787) Polyglycyl-TUBB6 [cytosol] (R-HSA-8867396) TUBB6 [cytosol] (R-HSA-191698) TUBB6 [axonemal microtubule] (R-HSA-5610438) Polyglutamyl-TUBB6 [cytosol] (R-HSA-8867399)	0.547	3
UniProt:Q13885 TUBB2A	6	TUBB2A [axonemal microtubule] (R-HSA-5610431) TUBB2A [cytosol] (R-HSA-191699) Polyglutamyl-TUBB2A [cytosol] (R-HSA-8867392) Polyglycyl-TUBB2A [cytosol] (R-HSA-8867466) TUBB2A unfolded [cytosol] (R-HSA-392776) TUBB2A folding intermediate [cytosol] (R-HSA-392802)	0.547	3
UniProt:Q8N6T3-2 ARFGAP1			0.544	6
UniProt:Q05193 DNM1	3	DNM1 [cytosol] (R-HSA-2213182) DNM1 [lysosomal membrane] (R-HSA-196150) DNM1 [plasma membrane] (R-HSA-177488)	0.543	4
UniProt:Q92997 DVL3	4	p-DVL3 [cytosol] (R-HSA-201680) pp-DVL3 [cytosol] (R-HSA-3772400) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.543	4
UniProt:O14640-2 DVL1			0.543	7
UniProt:Q9Y6I7 WSB1	1	WSB1 [cytosol] (R-HSA-976016)	0.543	5
UniProt:Q9DBG3	5	Ap2b1 [endocytic vesicle membrane] (R-MMU-416642) Ap2b1 [endolysosome membrane] (R-MMU-6784827) Ap2b1 [plasma membrane] (R-MMU-167690) Ap2b1 [clathrin-coated endocytic vesicle membrane] (R-MMU-2130489) Ap2b1 [cytosol] (R-MMU-182166)	0.527	2
UniProt:P62263 RPS14	2	RPS14 [cytosol] (R-HSA-72333) RPS14 [nucleoplasm] (R-HSA-6790669)	0.527	3
UniProt:P46460	1	Nsf [cytosol] (R-MMU-264471)	0.527	5
UniProt:Q9JIS5 SV2A			0.527	2
UniProt:P00338 LDHA	1	LDHA [cytosol] (R-HSA-70502)	0.527	3
UniProt:Q68FD5	6	Cltc [cytosol] (R-MMU-350824) Cltc [lysosomal membrane] (R-MMU-2980660) Cltc [trans-Golgi network membrane] (R-MMU-2130474) Cltc [endolysosome membrane] (R-MMU-8870827) Cltc [clathrin-coated endocytic vesicle membrane] (R-MMU-5138450) Cltc [plasma membrane] (R-MMU-2980668)	0.527	2
UniProt:P62259 Ywhae	1	14-3-3 epsilon [cytosol] (R-MMU-1445119)	0.527	2
UniProt:P14618 PKM	3	PKM [extracellular region] (R-HSA-6806491) PKM [ficolin-1-rich granule lumen] (R-HSA-6801387) PKM [secretory granule lumen] (R-HSA-6801401)	0.527	3
UniProt:P39023 RPL3	1	RPL3 [cytosol] (R-HSA-72448)	0.527	3
UniProt:Q16531 DDB1	1	DDB1 [nucleoplasm] (R-HSA-53489)	0.527	3
UniProt:Q01813 PFKP	1	PFKP [cytosol] (R-HSA-71452)	0.527	3
UniProt:P62244 RPS15A	2	RPS15A [cytosol] (R-HSA-72345) RPS15A [nucleoplasm] (R-HSA-6791191)	0.527	3
UniProt:Q9Y3Z3 SAMHD1	1	SAMHD1 [nucleoplasm] (R-HSA-5624198)	0.527	3
UniProt:P11499	5	Hsp90ab1 [extracellular region] (R-MMU-6806463) Hsp90ab1 [ficolin-1-rich granule lumen] (R-MMU-6801491) Hsp90ab1 [secretory granule lumen] (R-MMU-6801477) Hsp90ab1 [cytosol] (R-MMU-419617) Hsp90ab1 [nucleoplasm] (R-MMU-5082399)	0.527	2
UniProt:O00273 DFFA	6	DFFA(1-?) [nucleoplasm] (R-HSA-211228) DFFA [cytosol] (R-HSA-211221) DFFA(225-331) [nucleoplasm] (R-HSA-211188) DFFA(118-224) [nucleoplasm] (R-HSA-211205) DFFA(118-331) [nucleoplasm] (R-HSA-211199) DFFA(1-117) [nucleoplasm] (R-HSA-211185)	0.527	3
UniProt:O00159 MYO1C	1	MYO1C [cytosol] (R-HSA-1449619)	0.527	3
UniProt:P10155 RO60			0.527	3
UniProt:P61264	1	Stx1b [plasma membrane] (R-MMU-181479)	0.527	2
UniProt:Q9UKV3 ACIN1	3	ACIN1(1094-1341) [cytosol] (R-HSA-212516) ACIN1 [cytosol] (R-HSA-212519) ACIN1(1-1093) [cytosol] (R-HSA-212520)	0.527	3
UniProt:P62913 RPL11	1	RPL11 [cytosol] (R-HSA-72406)	0.527	3
UniProt:O94906 PRPF6	1	PRPF6 [nucleoplasm] (R-HSA-71881)	0.527	3
UniProt:P12004 PCNA	5	K63polyUb-K164-PCNA [nucleoplasm] (R-HSA-8943000) SUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-HSA-5653768) MonoUb-K164-PCNA [nucleoplasm] (R-HSA-5651986) PCNA [nucleoplasm] (R-HSA-68439)	0.527	3
UniProt:Q96T76 MMS19	1	MMS19 [cytosol] (R-HSA-2161121)	0.527	3
UniProt:Q9NU22 MDN1			0.527	3
UniProt:P31689 DNAJA1	1	DNAJA1 [cytosol] (R-HSA-3371544)	0.527	3
UniProt:P78527 PRKDC	4	PRKDC [nucleoplasm] (R-HSA-62161) p-T2609,S2612,T2638,T2647-PRKDC [nucleoplasm] (R-HSA-76302) PRKDC [cytosol] (R-HSA-3134816) K48polyUb-PRKDC [cytosol] (R-HSA-8938766)	0.527	3
UniProt:P23258 TUBG1	1	TUBG1 [cytosol] (R-HSA-379269)	0.527	3
UniProt:Q9P035 HACD3	1	PTPLAD1 [endoplasmic reticulum membrane] (R-HSA-5676074)	0.527	3
UniProt:P26641 EEF1G	1	EEF1G [cytosol] (R-HSA-156925)	0.527	3
UniProt:Q16186 ADRM1	1	ADRM1 [cytosol] (R-HSA-5665939)	0.527	3
UniProt:P38646 HSPA9	6	HSPA9 [cytosol] (R-HSA-5251993) HSPA9 [nucleoplasm] (R-HSA-5252128) HSPA9 [mitochondrial matrix] (R-HSA-8878802) HSPA9(1-679) [mitochondrial intermembrane space] (R-HSA-1267968) HSPA9 [mitochondrial inner membrane] (R-HSA-1252206) HSPA9(1-679) [cytosol] (R-HSA-1267964)	0.527	3
UniProt:P83731 RPL24	1	RPL24 [cytosol] (R-HSA-72434)	0.527	3
UniProt:P63261 ACTG1	3	ACTG1 [cytosol] (R-HSA-201858) ACTG1 [lysosomal membrane] (R-HSA-196169) ACTG1 [plasma membrane] (R-HSA-196044)	0.527	3
UniProt:P49411 TUFM	1	TUFM [mitochondrial matrix] (R-HSA-5389846)	0.527	3
UniProt:P50402 EMD	3	EMD [cytosol] (R-HSA-9613988) EMD [endoplasmic reticulum membrane] (R-HSA-9613998) EMD [nuclear envelope] (R-HSA-201573)	0.527	3
UniProt:O43795 MYO1B			0.527	3
UniProt:Q96EY7 PTCD3	1	PTCD3 [mitochondrial inner membrane] (R-HSA-5368165)	0.527	3
UniProt:P12270 TPR	3	TPR L458P [nucleoplasm] (R-HSA-5661460) TPR M489P [nucleoplasm] (R-HSA-5661477) TPR [nucleoplasm] (R-HSA-157692)	0.527	3
UniProt:Q13435 SF3B2	1	SF3B2 [nucleoplasm] (R-HSA-71971)	0.527	3
UniProt:P07901 Hsp90aa1	7	Hsp90aa1 [extracellular region] (R-MMU-3221946) Hsp90aa1 [ficolin-1-rich granule lumen] (R-MMU-6801470) Hsp90aa1 [secretory granule lumen] (R-MMU-6801515) Hsp90aa1 [plasma membrane] (R-MMU-534996) Hsp90aa1 [nucleoplasm] (R-MMU-5082401) Hsp90aa1 [cytosol] (R-MMU-5605275) Hsp90aa1 [cytosol] (R-MMU-192864)	0.527	2
UniProt:Q9UBF2 COPG2	4	COPG2 [transport vesicle] (R-HSA-6808753) COPG2 [endoplasmic reticulum membrane] (R-HSA-6810962) COPG2 [cytosol] (R-HSA-6807747) COPG2 [Golgi membrane] (R-HSA-6808751)	0.527	3
UniProt:P09543 CN37			0.527	3
UniProt:Q86WJ1 CHD1L	1	CHD1L [nucleoplasm] (R-HSA-5688916)	0.527	3
UniProt:P68373 Tuba1c	6	Tuba1c [axonemal microtubule] (R-MMU-5624856) Tuba1c [cytosol] (R-MMU-5618314) Tuba1c [cytosol] (R-MMU-8867405) Tuba1c [cytosol] (R-MMU-8867401) Tuba1c [axonemal microtubule] (R-MMU-5610439) Tubulin alpha-1C chain [cytosol] (R-MMU-2316300)	0.527	2
UniProt:Q8N1G4 LRC47			0.527	3
UniProt:Q9Y2L1 DIS3	2	DIS3 [cytosol] (R-HSA-429935) DIS3 [nucleoplasm] (R-HSA-6791517)	0.527	3
UniProt:Q8NI60 COQ8A			0.527	3
UniProt:Q13200 PSMD2	5	PSMD2 [extracellular region] (R-HSA-6806479) PSMD2 [ficolin-1-rich granule lumen] (R-HSA-6800435) PSMD2 [secretory granule lumen] (R-HSA-6800919) PSMD2 [nucleoplasm] (R-HSA-174311) PSMD2 [cytosol] (R-HSA-68796)	0.527	3
UniProt:Q9UN37 VPS4A	1	VPS4A [cytosol] (R-HSA-917732)	0.527	3
UniProt:O15269 SPTLC1	1	PXLP-K-SPTLC1 [endoplasmic reticulum membrane] (R-HSA-428155)	0.527	3
UniProt:P99024 Tubb5	4	unfolded beta 5 tubulin [cytosol] (R-MMU-391398) beta 5 tubulin [cytosol] (R-MMU-391459) Tubb5 [azurophil granule lumen] (R-MMU-6799370) Tubb5 [extracellular region] (R-MMU-380317)	0.527	2
UniProt:Q71U36 TUBA1A	9	Ac K40 TUBA1A [axonemal microtubule] (R-HSA-5624852) AcK-TUBA1A [cytosol] (R-HSA-5618312) TUBA1A folding intermediate [cytosol] (R-HSA-392805) TUBA1A unfolded [cytosol] (R-HSA-392767) L-isoglutamyl polyglycyl-TUBA1A [cytosol] (R-HSA-8867428) TUBA1A [cytosol] (R-HSA-191689) TUBA1A [axonemal microtubule] (R-HSA-5610433) TUBA1A(1-450) [cytosol] (R-HSA-8955577) Polyglutamyl-TUBA1A [cytosol] (R-HSA-8867408)	0.527	2
UniProt:P57740 NUP107	2	NUP107 [cytosol] (R-HSA-376241) NUP107 [nuclear envelope] (R-HSA-157717)	0.527	3
UniProt:Q9H9B4 SFXN1			0.527	3
UniProt:P07814 EPRS1	1	EPRS [cytosol] (R-HSA-379649)	0.527	3
UniProt:P62081 RPS7	2	RPS7 [cytosol] (R-HSA-72383) RPS7 [nucleoplasm] (R-HSA-6790635)	0.527	3
UniProt:P49792 RANBP2	4	SUMO1-K2592,K2650,K2723-RANBP2 [nuclear envelope] (R-HSA-4551599) SUMO2-K2652,K2725-RANBP2 [nuclear envelope] (R-HSA-4551720) RANBP2 [cytosol] (R-HSA-157703) RANBP2 [nuclear envelope] (R-HSA-2993756)	0.527	3
UniProt:Q15393 SF3B3	1	SF3B3 [nucleoplasm] (R-HSA-71973)	0.527	3
UniProt:Q969V3 NCLN			0.527	3
UniProt:O95831 AIFM1			0.527	3
UniProt:Q14974 KPNB1	5	KPNB1 [nucleoplasm] (R-HSA-180714) KPNB1 [cytosol] (R-HSA-180733) KPNB1 [specific granule lumen] (R-HSA-6799646) KPNB1 [extracellular region] (R-HSA-6806306) KPNB1 [ficolin-1-rich granule lumen] (R-HSA-6800978)	0.527	3
UniProt:Q13185 CBX3	1	CBX3 [nucleoplasm] (R-HSA-427386)	0.527	3
UniProt:O00139 KIF2A	1	KIF2A [cytosol] (R-HSA-376232)	0.527	3
UniProt:Q9H4L4 SENP3	1	SENP3 [nucleoplasm] (R-HSA-2984296)	0.527	3
UniProt:P84098 RPL19	1	RPL19 [cytosol] (R-HSA-72424)	0.527	3
UniProt:Q61548	1	Snap91 [cytosol] (R-MMU-8867597)	0.527	2
UniProt:P49368 CCT3	1	CCT3 [cytosol] (R-HSA-390463)	0.527	3
UniProt:Q12769 NUP160	2	NUP160 [cytosol] (R-HSA-376253) NUP160 [nuclear envelope] (R-HSA-157721)	0.527	3
UniProt:O35526 Stx1a	3	Syntaxin-1A [plasma membrane] (R-MMU-216884) Stx1a [cytosol] (R-MMU-9609866) Stx1a [plasma membrane] (R-MMU-449128)	0.527	2
UniProt:Q02978 SLC25A11	1	SLC25A11 [mitochondrial inner membrane] (R-HSA-198451)	0.527	3
UniProt:P61247 RPS3A	2	RPS3A [cytosol] (R-HSA-72373) RPS3A [nucleoplasm] (R-HSA-6791182)	0.527	3
UniProt:Q5S006	1	Lrrk2 [cytosol] (R-MMU-5661173)	0.527	2
UniProt:Q7L576 CYFIP1	5	CYFIP1 [secretory granule lumen] (R-HSA-6800940) CYFIP1 [specific granule lumen] (R-HSA-6800167) CYFIP1 [extracellular region] (R-HSA-6800473) CYFIP1 [tertiary granule lumen] (R-HSA-6800176) CYFIP1 [cytosol] (R-HSA-5672575)	0.527	3
UniProt:P48047 ATP5PO	1	ATP5O [mitochondrial inner membrane] (R-HSA-164533)	0.527	3
UniProt:P51571 SSR4	1	SSR4 [endoplasmic reticulum membrane] (R-HSA-265026)	0.527	3
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.527	3
UniProt:Q15008 PSMD6	5	PSMD6 [extracellular region] (R-HSA-6806486) PSMD6 [ficolin-1-rich granule lumen] (R-HSA-6800440) PSMD6 [secretory granule lumen] (R-HSA-6801036) PSMD6 [nucleoplasm] (R-HSA-174316) PSMD6 [cytosol] (R-HSA-68804)	0.527	3
UniProt:P30050 RPL12	1	RPL12 [cytosol] (R-HSA-72408)	0.527	3
UniProt:P13995 MTHFD2	1	MTHFD2 [mitochondrial matrix] (R-HSA-6801347)	0.527	3
UniProt:P13639 EEF2	10	EEF2 [extracellular region] (R-HSA-6806499) EEF2 [secretory granule lumen] (R-HSA-6801504) EEF2 [ficolin-1-rich granule lumen] (R-HSA-6801513) aminocarboxypropyl EEF2 [cytosol] (R-HSA-5358478) Me-diphthine EEF2 [cytosol] (R-HSA-5367025) nascent EEF2 [cytosol] (R-HSA-5358472) diphthine EEF2 [cytosol] (R-HSA-5358501) EEF2 [cytosol] (R-HSA-156901) ADP-ribo-EEF2 [cytosol] (R-HSA-5334764) Me3K525-EEF2 [cytosol] (R-HSA-8932237)	0.527	3
UniProt:Q9H936 SLC25A22	1	SLC25A22 [mitochondrial inner membrane] (R-HSA-5216091)	0.527	3
UniProt:P11216 PYGB	4	PXLP-PYGB [azurophil granule lumen] (R-HSA-6799164) PXLP-PYGB [extracellular region] (R-HSA-6801536) PXLP-p-S14-PYGB [cytosol] (R-HSA-71868) PXLP-PYGB [cytosol] (R-HSA-71862)	0.527	3
UniProt:P43246 MSH2	3	MSH2 GLN601TER [nucleoplasm] (R-HSA-5577243) MSH2 [nucleoplasm] (R-HSA-5357525) MSH2 R406* [nucleoplasm] (R-HSA-5575594)	0.527	3
UniProt:Q5UIP0 RIF1	1	RIF1 [nucleoplasm] (R-HSA-480742)	0.527	3
UniProt:Q14008 CKAP5	1	CKAP5 [cytosol] (R-HSA-377729)	0.527	3
UniProt:Q9Y4W2 LAS1L	1	LAS1L [nucleoplasm] (R-HSA-6791521)	0.527	3
UniProt:P61221 ABCE1	2	ABCE1 [cytosol] (R-HSA-8985209) ABCE1 [mitochondrial matrix] (R-HSA-5216010)	0.527	3
UniProt:P42166 TMPO			0.527	3
UniProt:Q13724 MOGS	3	MOGS R486T [endoplasmic reticulum membrane] (R-HSA-4839818) MOGS F652L [endoplasmic reticulum membrane] (R-HSA-4839779) MOGS [endoplasmic reticulum membrane] (R-HSA-532676)	0.527	3
UniProt:Q14498 RBM39			0.527	3
UniProt:P05213 Tuba1b	7	Tuba1b [axonemal microtubule] (R-MMU-5624854) Tuba1b [cytosol] (R-MMU-5618285) unfolded alpha 2 tubulin [cytosol] (R-MMU-391420) Tuba1b [cytosol] (R-MMU-8867436) Tuba1b [cytosol] (R-MMU-8867435) Tuba1b [axonemal microtubule] (R-MMU-5610434) Tubulin alpha-1B chain [cytosol] (R-MMU-2316298)	0.527	2
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.527	3
UniProt:P62266 RPS23	2	RPS23 [cytosol] (R-HSA-72353) RPS23 [nucleoplasm] (R-HSA-6791209)	0.525	2
UniProt:P62750 RPL23A	1	RPL23A [cytosol] (R-HSA-72432)	0.525	2
UniProt:P50914 RPL14	1	RPL14 [cytosol] (R-HSA-72414)	0.525	2
UniProt:P07195 LDHB	1	LDHB [cytosol] (R-HSA-70503)	0.525	2
UniProt:P12369 Prkar2b	3	Prkar2b [ciliary base] (R-RNO-5610414) cAMP-dependent protein kinase type II-beta regulatory subunit [cytosol] (R-RNO-446975) Prkar2b [cytosol] (R-RNO-57842)	0.524	3
UniProt:P30275	1	Ckmt1 [mitochondrial inner membrane] (R-MMU-200361)	0.524	2
UniProt:P61021	6	Rab5b [early endosome membrane] (R-MMU-8875327) Rab5b [clathrin-coated endocytic vesicle membrane] (R-MMU-8871126) Rab5b [cytosol] (R-MMU-8870434) Rab5b [cytosol] (R-MMU-8870412) Rab5b [plasma membrane] (R-MMU-6804984) Rab5b [secretory granule membrane] (R-MMU-6804966)	0.499	2
UniProt:Q6IQ22 RAB12	3	GGC-RAB12 [cytosol] (R-HSA-8873777) GGC-RAB12 [recycling endosome membrane] (R-HSA-8876449) RAB12 [cytosol] (R-HSA-8873672)	0.499	2
UniProt:Q13158 FADD	1	FADD [cytosol] (R-HSA-54639)	0.499	4
UniProt:Q13509 TUBB3	6	TUBB3 unfolded [cytosol] (R-HSA-392770) TUBB3 folding intermediate [cytosol] (R-HSA-392806) Polyglycyl-TUBB3 [cytosol] (R-HSA-8867372) TUBB3 [cytosol] (R-HSA-190532) TUBB3 [axonemal microtubule] (R-HSA-5610436) Polyglutamyl-TUBB3 [cytosol] (R-HSA-8867464)	0.482	2
UniProt:P52564 MAP2K6	3	p-S207,T211-MAP2K6 [cytosol] (R-HSA-206255) p-S207,T211-MAP2K6 [nucleoplasm] (R-HSA-450258) MAP2K6 [cytosol] (R-HSA-167998)	0.463	4
UniProt:Q91YQ1	2	Rab29 [cytosol] (R-MMU-8873713) Rab29 [cytosol] (R-MMU-8873957)	0.463	2
UniProt:P13473 LAMP2	5	LAMP2 [azurophil granule membrane] (R-HSA-6799150) LAMP2 [platelet dense granule membrane] (R-HSA-58648) LAMP2 [plasma membrane] (R-HSA-114679) LAMP2 [ficolin-1-rich granule membrane] (R-HSA-6800941) LAMP2 [lysosomal membrane] (R-HSA-2029007)	0.463	2
UniProt:Q63481	2	Rab29 [cytosol] (R-RNO-8873713) Rab29 [cytosol] (R-RNO-8873957)	0.463	3
UniProt:O95140 MFN2	2	K48polyUb-MFN2 [mitochondrial outer membrane] (R-HSA-5205668) MFN2 [mitochondrial outer membrane] (R-HSA-992714)	0.463	3
UniProt:Q811U4	2	Mfn1 [mitochondrial outer membrane] (R-MMU-5205679) Mfn1 [mitochondrial outer membrane] (R-MMU-992745)	0.463	3
UniProt:Q32KD4	6	AGO1 [nucleoplasm] (R-DME-5578701) AGO1 [nucleoplasm] (R-DME-5578686) AGO1 [cytosol] (R-DME-209723) AGO1 [cytosol] (R-DME-210616) AGO1 [cytosol] (R-DME-210612) AGO1 [cytosol] (R-DME-210615)	0.463	2
UniProt:P46940 IQGAP1	3	IQGAP1 [secretory granule membrane] (R-HSA-6804803) IQGAP1 [cytosol] (R-HSA-5626371) IQGAP1 [plasma membrane] (R-HSA-381681)	0.462	2
UniProt:P30153 PPP2R1A	2	PPP2R1A [nucleoplasm] (R-HSA-165968) PPP2R1A [cytosol] (R-HSA-165982)	0.462	2
UniProt:Q92973 TNPO1	2	TNPO1 [cytosol] (R-HSA-180743) TNPO1 [cilium] (R-HSA-5624896)	0.462	2

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