RORA, EP300, PPARGC1A bind NR1D1 gene

Stable Identifier
R-HSA-5663273
Type
Reaction [binding]
Species
Homo sapiens
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As inferred from mouse, RORA binds RRE DNA elements and recruits the coactivators PGC-1alpha (PPARGC1A) and p300 (EP300, a histone acetylase). RORA binds the NR1D1 (REV-ERBA) promoter and activates transcription.

Literature References
PubMed ID Title Journal Year
12377782 Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha

Raspè, E, Mautino, G, Duval, C, Fontaine, C, Duez, H, Barbier, O, Monte, D, Fruchart, J, Fruchart, JC, Staels, B

J Biol Chem 2002
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