Reactome: A Curated Pathway Database

FMNL3 binds RHOC:GTP

Stable Identifier
R-HSA-5665761
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

FMNL3 binds activated (GTP-bound) RHOC. RHOC-mediated activation of FMNL3 promotes polarized cell migration which may be involved in cancer cell invasion (Vega et al. 2011). Myristoylation of the N-terminal glycine may be required for the full activation of FMNL3 (Moriya et al. 2012).

Literature References
Participants
Participant Of
Orthologous Events