Profilin:G-actin binds MKL1

Stable Identifier
R-HSA-5666001
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
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Summation

MKL1 (MAL) transcription cofactor is negatively regulated by binding to nonpolymerized actin (G-actin) (Miralles et al. 2003).

Literature References
PubMed ID Title Journal Year
12732141 Actin dynamics control SRF activity by regulation of its coactivator MAL

Miralles, F, Posern, G, Zaromytidou, AI, Treisman, R

Cell 2003
Participants
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Orthologous Events
Profilin:G-actin binds MKL1 (Bos taurus)
Profilin:G-actin binds MKL1 (Canis familiaris)
Profilin:G-actin binds MKL1 (Danio rerio)
Profilin:G-actin binds MKL1 (Mus musculus)
Profilin:G-actin binds MKL1 (Rattus norvegicus)
Profilin:G-actin binds MKL1 (Sus scrofa)
Profilin:G-actin binds MKL1 (Xenopus tropicalis)
Authored