Profilin:G-actin binds MKL1

Stable Identifier
R-HSA-5666001
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
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Summation

MKL1 (MAL) transcription cofactor is negatively regulated by binding to nonpolymerized actin (G-actin) (Miralles et al. 2003).

Literature References
PubMed ID Title Journal Year
12732141 Actin dynamics control SRF activity by regulation of its coactivator MAL Cell 2003
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
Profilin:G-actin binds MKL1 (Bos taurus)
Profilin:G-actin binds MKL1 (Canis familiaris)
Profilin:G-actin binds MKL1 (Danio rerio)
Profilin:G-actin binds MKL1 (Mus musculus)
Profilin:G-actin binds MKL1 (Rattus norvegicus)
Profilin:G-actin binds MKL1 (Sus scrofa)
Profilin:G-actin binds MKL1 (Xenopus tropicalis)