RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes

Stable Identifier
R-HSA-5666070
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Activated RHOB (RHOB:GTP) recruits DIAPH1 or DIAPH3 to endosomes where they regulate actin coat formation around endosomes and endosome motility/trafficking (Fernandez-Borja et al. 2005, Wallar et al. 2007).

Literature References
PubMed ID Title Journal Year
17198702 RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking

Wallar, BJ, Deward, AD, Resau, JH, Alberts, AS

Exp. Cell Res. 2007
15944396 RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1

Fernandez-Borja, M, Janssen, L, Verwoerd, D, Hordijk, P, Neefjes, J

J. Cell. Sci. 2005
Participants
Participant Of
Orthologous Events
Authored