RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes

Stable Identifier
R-HSA-5666070
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, endosome membrane
ReviewStatus
5/5
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RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes
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Activated RHOB (RHOB:GTP) recruits DIAPH1 or DIAPH3 to endosomes where they regulate actin coat formation around endosomes and endosome motility/trafficking (Fernandez-Borja et al. 2005, Wallar et al. 2007).
Literature References
PubMed ID Title Journal Year
15944396 RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1

Janssen, L, Fernandez-Borja, M, Neefjes, J, Hordijk, P, Verwoerd, D

J. Cell. Sci. 2005
17198702 RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking

Wallar, BJ, Alberts, AS, Deward, AD, Resau, JH

Exp. Cell Res. 2007
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Output
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Orthologous Events
RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Caenorhabditis elegans)
RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Canis familiaris)
RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Drosophila melanogaster)
RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Gallus gallus)
RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Mus musculus)
RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Rattus norvegicus)
RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Sus scrofa)
Authored
Orlic-Milacic, M  (2014-10-24)
Rivero Crespo, F  (2014-12-26)
Created
Orlic-Milacic, M  (2015-01-21)
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