Reactome: A Curated Pathway Database

RHOD:GTP recruits DAIPH2-3 to endosomes

Stable Identifier
R-HSA-5666088
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Activated RHOD (RHOD:GTP) binds DIAPH2 transcription isoform DIAPH2-3 (DIAPH2C) and recruits it to endosomes. RHOD and DIAPH2 regulate endosome motility through SRC-dependent regulation of actin dynamics (Gasman et al. 2003).

Literature References
Participants
Participant Of
Orthologous Events