Reactome | RTKN [cytosol]

RTKN [cytosol]

Stable Identifier

R-HSA-5666184

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Rhotekin, RTKN1

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External Reference Information

External Reference

UniProt:Q9BST9 RTKN

Gene Names

RTKN, RTKN1

Chain

chain:1-563

Reference Genes

BioGPS Gene:6242 RTKN

COSMIC (genes):RTKN RTKN

CTD Gene:6242 RTKN

dbSNP Gene:6242 RTKN

ENSEMBL:ENSG00000114993 RTKN

HGNC:10466 RTKN

Monarch:6242 RTKN

NCBI Gene:6242 RTKN

OMIM:602288 RTKN

UCSC:Q9BST9 RTKN

Reference Transcript

Other Identifiers

11722873_a_at

11724607_a_at

11741087_a_at

11758910_at

16899224

225150_PM_s_at

225150_s_at

225151_PM_at

225151_at

239653_PM_at

239653_at

2560078

2560079

2560080

2560081

2560082

2560083

2560084

2560085

2560086

2560088

2560089

2560090

2560091

2560092

2560093

2560094

2560095

2560096

2560097

2560098

2560099

2560100

2560101

2560102

2560103

2560104

2560105

2560106

2560110

2560111

2560112

2560113

2560114

2560115

2560116

2560117

2560118

2560119

2560120

2560121

53180_at

6242

8053142

85934_at

85936_g_at

85938_at

89137_at

89792_at

A_23_P120056

GE634970

GE88594

GO:0000281

GO:0000910

GO:0000915

GO:0005095

GO:0005515

GO:0005525

GO:0005575

GO:0005826

GO:0005829

GO:0006915

GO:0007010

GO:0007165

GO:0007266

GO:0012501

GO:0031106

GO:0031267

GO:0042981

GO:0098772

HMNXSV003017425

HMNXSV003023903

HMNXSV003037181

Hs.192854.0.A1_3p_at

Hs.58215.0.S1_3p_at

Hs.58215.0.S2_3p_a_at

Hs.58215.0.S2_3p_x_at

ILMN_1680591

ILMN_1688256

ILMN_1809336

ILMN_2392818

PH_hs_0003741

TC02001996.hg

Participates

as a member of

as a component of

as an input of

RTKN binds RHOA, RHOC or RHOB (Homo sapiens)

Inferred To

RTKN [cytosol] (Bos taurus)

RTKN [cytosol] (Caenorhabditis elegans)

RTKN [cytosol] (Canis familiaris)

RTKN [cytosol] (Gallus gallus)

RTKN [cytosol] (Sus scrofa)

mid1 [cytosol] (Schizosaccharomyces pombe)

Rtkn [cytosol] (Mus musculus)

Rtkn [cytosol] (Rattus norvegicus)

rtkn [cytosol] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000305557, ENSP00000272430, ENSP00000233330, ENSP00000305298, ENST00000233330, ENST00000272430

OpenTargets

ENSG00000114993

HPA

ENSG00000114993-RTKN

PRO

Q9BST9

Pharos - Targets

Q9BST9

HMDB Protein

HMDBP08570

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61586 RHOA	6	RHOA [plasma membrane] (R-HSA-194510) RHOA [cell junction] (R-HSA-2134503) RHOA [cytosol] (R-HSA-194866) RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082)	0.912	9
UniProt:Q9QUI0 Rhoa	6	RHOA [endoplasmic reticulum membrane] (R-MMU-5672082) RHOA [secretory granule membrane] (R-MMU-6804980) RHOA [ficolin-1-rich granule membrane] (R-MMU-6804971) RHOA [cytosol] (R-MMU-194866) RHOA [cell junction] (R-MMU-2134503) Rhoa [plasma membrane] (R-MMU-5625902)	0.589	2
UniProt:P08134 RHOC	3	RHOC [plasma membrane] (R-HSA-194870) RHOC [cytosol] (R-HSA-194853) RHOC [endoplasmic reticulum membrane] (R-HSA-9714362)	0.527	2
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.527	2
UniProt:O60504-2 SORBS3			0.524	3
UniProt:O60504 SORBS3	1	SORBS3 [cytosol] (R-HSA-445805)	0.508	3

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