Reactome | RHOA:GTP:RTKN binds LIN7B

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RHOA:GTP:RTKN binds LIN7B

Stable Identifier

R-HSA-5666197

Type

Reaction

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Summation

RTKN (rhotekin) associated with activated RHOA (RHOA:GTP) binds LIN7B, a cell polarity-related protein. Both LIN7B and RTKN are highly expressed in neurons (Sudo et al. 2006).

Literature References

PubMed ID	Title	Journal	Year
16979770	Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons	Neurosci. Res.	2006

Participants

Input

Output

RHOA:GTP:RTKN:LIN7B [plasma membrane] (Homo sapiens)

Participant Of

hasEvent

RHO GTPases Activate Rhotekin and Rhophilins

Orthologous Events

RHOA:GTP:RTKN binds LIN7B (Bos taurus)

RHOA:GTP:RTKN binds LIN7B (Canis familiaris)

RHOA:GTP:RTKN binds LIN7B (Danio rerio)

RHOA:GTP:RTKN binds LIN7B (Gallus gallus)

RHOA:GTP:RTKN binds LIN7B (Mus musculus)

RHOA:GTP:RTKN binds LIN7B (Rattus norvegicus)

RHOA:GTP:RTKN binds LIN7B (Sus scrofa)

RHOA:GTP:RTKN binds LIN7B (Xenopus tropicalis)