Reactome: A Curated Pathway Database

RHOA:GTP:RTKN binds TAX1BP3

Stable Identifier
R-HSA-5666216
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The PDZ domain of TAX1BP3 (TIP-1) binds the C-terminus of RTKN (rhotekin) associated with activated RHOA (RHOA:GTP). Binding of TAX1BP3 to the RHOA:GTP:RTKN complex stimulates SRF-mediated transcription through an unknown mechanism (Reynaud et al. 2000).

Literature References
Participants
Participant Of
Orthologous Events