Reactome | RUNX1 [plasma membrane]

Stable Identifier

R-HSA-5667138

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Runt-related transcription factor 1, RUNX1_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:Q9H2X6 HIPK2

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External Reference Information

External Reference

UniProt:Q01196 RUNX1

Gene Names

RUNX1, AML1, CBFA2

Chain

chain:1-453

Reference Genes

COSMIC (genes):RUNX1 RUNX1

dbSNP Gene:861 RUNX1

ENSEMBL:ENSG00000159216 RUNX1

This entity regulates

Negatively

Other forms of this molecule

p-S249,S273,S276-RUNX1 [nucleoplasm]

p-7Y-RUNX1 [nucleoplasm]

MeR206,MeR210-RUNX1 [nucleoplasm]

RUNX1 [nucleoplasm]

Inferred To

RUNX1 [plasma membrane] (Bos taurus)

RUNX1 [plasma membrane] (Danio rerio)

RUNX1 [plasma membrane] (Gallus gallus)

RUNX1 [plasma membrane] (Mus musculus)

RUNX1 [plasma membrane] (Rattus norvegicus)

RUNX1 [plasma membrane] (Sus scrofa)

RUNX1 [plasma membrane] (Xenopus tropicalis)

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13951 CBFB	1	CBFB [nucleoplasm] (R-HSA-8865293)	0.872	7
UniProt:Q9H2X6 HIPK2	3	p-HIPK2 [nucleoplasm] (R-HSA-6799375) HIPK2 [nucleoplasm] (R-HSA-3215222) monoSUMO1-K32-HIPK2 [nucleoplasm] (R-HSA-4090405)	0.639	4
UniProt:Q00534 CDK6	3	p-T177-CDK6 [nucleoplasm] (R-HSA-69628) CDK6 [nucleoplasm] (R-HSA-141283) CDK6 [cytosol] (R-HSA-68336)	0.628	5
UniProt:P17542 TAL1	1	TAL1 [nucleoplasm] (R-HSA-8956511)	0.623	3
UniProt:Q15723 ELF2	1	ELF2 [nucleoplasm] (R-HSA-8938898)	0.544	2
UniProt:Q9GZV5 WWTR1	3	WWTR1 [nucleoplasm] (R-HSA-1629775) WWTR1 [cytosol] (R-HSA-1629773) p-S89-WWTR1 [cytosol] (R-HSA-2028665)	0.527	2

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