TNFs bind their physiological receptors

Stable Identifier
R-HSA-5669034
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Pathway
Species
Homo sapiens
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Members of the tumour necrosis factor superfamily (TNFSF) and TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity. These members are implicated in various acquired or genetic human diseases, ranging from septic shock to autoimmune disorders, allograft rejection and cancer (So et al. 2006).

Literature References
PubMed ID Title Journal Year
16443545 Tumor necrosis factor/tumor necrosis factor receptor family members that positively regulate immunity

So, T, Lee, SW, Croft, M

Int. J. Hematol. 2006
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