Lymphotoxin-alpha (LTA) is a cytokine produced by lymphocytes that plays an important role in the inflammatory and immunologic response. LTA is a product of stimulated T cells and can help elicit cytotoxic effects on cancer cells. In its homotrimeric form, LTA binds the tumor necrosis factor receptor superfamily members TNFRSF1A, 1B and 14 (Aggarwal 2003).
