Lymphotoxin-alpha (LTA) is a cytokine produced by lymphocytes that plays an important role in the inflammatory and immunologic response. LTA is a product of stimulated T cells and can help elicit cytotoxic effects on cancer cells. In its homotrimeric form, LTA binds the tumor necrosis factor receptor superfamily members TNFRSF1A, 1B and 14 (Aggarwal 2003).
Aggarwal, BB
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