Reactome | PAQR3 [Golgi membrane]

PAQR3 [Golgi membrane]

Stable Identifier

R-HSA-5674103

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

RKTG

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6TCH7 PAQR3

Gene Names

PAQR3

Chain

chain:1-311

Reference Genes

BioGPS Gene:152559 PAQR3

COSMIC (genes):PAQR3 PAQR3

CTD Gene:152559 PAQR3

dbSNP Gene:152559 PAQR3

ENSEMBL:ENSG00000163291 PAQR3

HGNC:30130 PAQR3

KEGG Gene (Homo sapiens):152559 PAQR3

Monarch:152559 PAQR3

NCBI Gene:152559 PAQR3

OMIM:614577 PAQR3

UCSC:Q6TCH7 PAQR3

Reference Transcript

RefSeq:NM_001040202.1 PAQR3

Other Identifiers

0006200546

11725818_a_at

11725819_s_at

11725820_s_at

11725821_x_at

11746428_a_at

11763887_s_at

152559

1557576_at

16977217

213372_at

2774818

2774819

2774820

2774825

2774826

2774827

2774828

2774829

2774830

2774831

2774832

2774833

2774834

2774835

2774837

2774838

2774842

2774844

2774845

2774849

2774851

2774852

2774871

2774873

2774875

39600_at

8101237

82517_s_at

82519_at

A_23_P167276

A_23_P337875

A_33_P3292235

GE56337

GO:0000139

GO:0000165

GO:0001933

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005794

GO:0006464

GO:0007165

GO:0008150

GO:0010977

GO:0016020

GO:0016021

GO:0030154

GO:0033137

GO:0034067

GO:0038023

GO:0043226

GO:0043407

GO:0048856

HMNXSV003037864

HMNXSV003042805

Hs.26860.0.S1_3p_at

Hs2.374711.1.S1_3p_at

Hs2.374711.1.S1_3p_s_at

ILMN_1716071

ILMN_3261837

PH_hs_0024063

TC04001325.hg

Participates

as a component of

PAQR3:inactive RAFs [Golgi membrane] (Homo sapiens)

as an input of

PAQR3 binds inactive RAFs (Homo sapiens)

Inferred To

Dmel\CG7530 [Golgi membrane] (Drosophila melanogaster)

Paqr3 [Golgi membrane] (Mus musculus)

Paqr3 [Golgi membrane] (Rattus norvegicus)

paqr-3 [Golgi membrane] (Caenorhabditis elegans)

paqr3a [Golgi membrane] (Danio rerio)

IZH2 [Golgi membrane] (Saccharomyces cerevisiae)

IZH1 [Golgi membrane] (Saccharomyces cerevisiae)

PAQR3 [Golgi membrane] (Bos taurus)

PAQR3 [Golgi membrane] (Canis familiaris)

PAQR3 [Golgi membrane] (Dictyostelium discoideum)

PAQR3 [Golgi membrane] (Gallus gallus)

PAQR3 [Golgi membrane] (Schizosaccharomyces pombe)

PAQR3 [Golgi membrane] (Sus scrofa)

IZH3 [Golgi membrane] (Saccharomyces cerevisiae)

Homologues of PAQR3 [Golgi membrane] (Dictyostelium discoideum)

Homologues of PAQR3 [Golgi membrane] (Saccharomyces cerevisiae)

Homologues of PAQR3 [Golgi membrane] (Schizosaccharomyces pombe)

IZH4 [Golgi membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_001035292.1

OpenTargets

ENSG00000163291

HPA

ENSG00000163291-PAQR3

GeneCards

Q6TCH7

Ensembl

ENSP00000421981, ENSP00000425080, ENST00000515853, ENSP00000426875, ENSP00000422357, ENST00000512733, ENSP00000378959, ENST00000512760, ENST00000395594, ENSG00000163291, ENST00000511594

PRO

Q6TCH7

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04049 RAF1	54	p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098) p-S621-RAF1 G361A [cytosol] (R-HSA-9656092) p-S621-RAF1 G370R [cytosol] (R-HSA-9656094) p-S621-RAF1 D486G [cytosol] (R-HSA-9656085) p-S621-RAF1 T491R [cytosol] (R-HSA-9656145) p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol] (R-HSA-9656026) p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol] (R-HSA-9656070) p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol] (R-HSA-9656035) p-S338,Y341,S494,S621-RAF1 T491I [cytosol] (R-HSA-9656019) p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol] (R-HSA-9656029) p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol] (R-HSA-9656031) p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol] (R-HSA-9656023) p-S338,Y341,S494,S621 RAF1 T491R [cytosol] (R-HSA-9656017) p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol] (R-HSA-9656062) p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol] (R-HSA-9656041) p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol] (R-HSA-9656058) p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol] (R-HSA-9656043) p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol] (R-HSA-9656053) p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol] (R-HSA-9656037) p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol] (R-HSA-9656050) p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol] (R-HSA-9656067) p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol] (R-HSA-9656077) p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol] (R-HSA-9656047) p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol] (R-HSA-9656056) p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol] (R-HSA-9656074) p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol] (R-HSA-9656080) p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol] (R-HSA-9656065) RAF1 [cytosol] (R-HSA-167205) p-S338,Y340,Y341-RAF1 [cytosol] (R-HSA-5624465) p-S338-RAF1 [cytosol] (R-HSA-5624469) p-S621-RAF1 [plasma membrane] (R-HSA-206222) p-Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5675420) p-S259,S621-RAF1 [cytosol] (R-HSA-109786) hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S621-RAF1 [cytosol] (R-HSA-206028) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (R-HSA-5672664)	0.576	3

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