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PAQR3 [Golgi membrane]
Stable Identifier
R-HSA-5674103
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
RKTG
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
Negative regulation of MAPK pathway (Homo sapiens)
PAQR3 binds inactive RAFs (Homo sapiens)
PAQR3 [Golgi membrane] (Homo sapiens)
PAQR3:inactive RAFs [Golgi membrane] (Homo sapiens)
PAQR3 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6TCH7 PAQR3
Gene Names
PAQR3
Chain
chain:1-311
Reference Genes
BioGPS Gene:152559 PAQR3
COSMIC (genes):PAQR3 PAQR3
CTD Gene:152559 PAQR3
dbSNP Gene:152559 PAQR3
ENSEMBL:ENSG00000163291 PAQR3
HGNC:30130 PAQR3
KEGG Gene (Homo sapiens):152559 PAQR3
Monarch:152559 PAQR3
NCBI Gene:152559 PAQR3
OMIM:614577 PAQR3
UCSC:Q6TCH7 PAQR3
Reference Transcript
RefSeq:NM_001040202.1 PAQR3
Other Identifiers
0006200546
11725818_a_at
11725819_s_at
11725820_s_at
11725821_x_at
11746428_a_at
11763887_s_at
152559
1557576_at
16977217
213372_at
2774818
2774819
2774820
2774825
2774826
2774827
2774828
2774829
2774830
2774831
2774832
2774833
2774834
2774835
2774837
2774838
2774842
2774844
2774845
2774849
2774851
2774852
2774871
2774873
2774875
39600_at
8101237
82517_s_at
82519_at
A_23_P167276
A_23_P337875
A_33_P3292235
GE56337
GO:0000139
GO:0000165
GO:0001933
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005794
GO:0006464
GO:0007165
GO:0008150
GO:0010977
GO:0016020
GO:0016021
GO:0030154
GO:0033137
GO:0034067
GO:0038023
GO:0043226
GO:0043407
GO:0048856
Hs.26860.0.S1_3p_at
Hs2.374711.1.S1_3p_at
Hs2.374711.1.S1_3p_s_at
ILMN_1716071
ILMN_3261837
PH_hs_0024063
TC04001325.hg
Participant Of
hasComponent
PAQR3:inactive RAFs [Golgi membrane]
input
PAQR3 binds inactive RAFs
Inferred To
Dmel\CG7530 [Golgi membrane] (Drosophila melanogaster)
Paqr3 [Golgi membrane] (Mus musculus)
Paqr3 [Golgi membrane] (Rattus norvegicus)
paqr3b [Golgi membrane] (Danio rerio)
paqr-3 [Golgi membrane] (Caenorhabditis elegans)
paqr3 [Golgi membrane] (Xenopus tropicalis)
IZH2 [Golgi membrane] (Saccharomyces cerevisiae)
IZH1 [Golgi membrane] (Saccharomyces cerevisiae)
PAQR3 [Golgi membrane] (Bos taurus)
PAQR3 [Golgi membrane] (Canis familiaris)
PAQR3 [Golgi membrane] (Dictyostelium discoideum)
PAQR3 [Golgi membrane] (Gallus gallus)
PAQR3 [Golgi membrane] (Plasmodium falciparum)
PAQR3 [Golgi membrane] (Schizosaccharomyces pombe)
PAQR3 [Golgi membrane] (Sus scrofa)
IZH3 [Golgi membrane] (Saccharomyces cerevisiae)
Homologues of PAQR3 [Golgi membrane] (Dictyostelium discoideum)
Homologues of PAQR3 [Golgi membrane] (Saccharomyces cerevisiae)
Homologues of PAQR3 [Golgi membrane] (Schizosaccharomyces pombe)
IZH4 [Golgi membrane] (Saccharomyces cerevisiae)
Cross References
RefSeq
NP_001035292.1
OpenTargets
ENSG00000163291
GeneCards
Q6TCH7
HPA
ENSG00000163291-PAQR3
Ensembl
ENSP00000378959
,
ENSP00000425080
,
ENSP00000426875
,
ENSP00000422357
,
ENSG00000163291
,
ENSP00000421981
,
ENST00000511594
,
ENST00000395594
,
ENST00000515853
,
ENST00000512733
,
ENST00000512760
PRO
Q6TCH7
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04049 RAF1
54
p-S338,Y340,Y341-RAF1 [cytosol]
(R-HSA-5624465)
RAF1 [cytosol]
(R-HSA-167205)
p-S338-RAF1 [cytosol]
(R-HSA-5624469)
p-S621-RAF1 S259F [cytosol]
(R-HSA-9656124)
p-S621-RAF1 S257L [cytosol]
(R-HSA-9656121)
p-S621-RAF1 P261L [cytosol]
(R-HSA-9656106)
p-S621-RAF1 N262K [cytosol]
(R-HSA-9656101)
p-S621-RAF1 P261A [cytosol]
(R-HSA-9656103)
p-S621-RAF1 P261S [cytosol]
(R-HSA-9656113)
p-S621-RAF1 S259T [cytosol]
(R-HSA-9656130)
p-S621-RAF1 P261T [cytosol]
(R-HSA-9656115)
p-S621-RAF1 P261R [cytosol]
(R-HSA-9656110)
p-S621-RAF1 S259P [cytosol]
(R-HSA-9656127)
p-S621-RAF1 T260I [cytosol]
(R-HSA-9656136)
p-S621-RAF1 T260R [cytosol]
(R-HSA-9656139)
p-S621-RAF1 V263A [cytosol]
(R-HSA-9656148)
p-S621-RAF1 R256S [cytosol]
(R-HSA-9656119)
p-S621-RAF1 T491I [cytosol]
(R-HSA-9656143)
p-S621-RAF1 D486N [cytosol]
(R-HSA-9656088)
p-S621-RAF1 S427G [cytosol]
(R-HSA-9656134)
p-S621-RAF1 L613V [cytosol]
(R-HSA-9656098)
p-S621-RAF1 G361A [cytosol]
(R-HSA-9656092)
p-S621-RAF1 G370R [cytosol]
(R-HSA-9656094)
p-S621-RAF1 D486G [cytosol]
(R-HSA-9656085)
p-S621-RAF1 T491R [cytosol]
(R-HSA-9656145)
p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol]
(R-HSA-9656026)
p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol]
(R-HSA-9656070)
p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol]
(R-HSA-9656035)
p-S338,Y341,S494,S621-RAF1 T491I [cytosol]
(R-HSA-9656019)
p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol]
(R-HSA-9656029)
p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol]
(R-HSA-9656031)
p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol]
(R-HSA-9656023)
p-S338,Y341,S494,S621 RAF1 T491R [cytosol]
(R-HSA-9656017)
p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol]
(R-HSA-9656062)
p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol]
(R-HSA-9656041)
p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol]
(R-HSA-9656058)
p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol]
(R-HSA-9656043)
p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol]
(R-HSA-9656053)
p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol]
(R-HSA-9656037)
p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol]
(R-HSA-9656050)
p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol]
(R-HSA-9656067)
p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol]
(R-HSA-9656077)
p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol]
(R-HSA-9656047)
p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol]
(R-HSA-9656056)
p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol]
(R-HSA-9656074)
p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol]
(R-HSA-9656080)
p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol]
(R-HSA-9656065)
hyperphosphorylated RAF1 [plasma membrane]
(R-HSA-5675193)
p-S621-RAF1 [plasma membrane]
(R-HSA-206222)
p-Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5675420)
p-S259,S621-RAF1 [cytosol]
(R-HSA-109786)
p-S621-RAF1 [cytosol]
(R-HSA-206028)
p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5672665)
p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-HSA-5672664)
0.576
3
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