hyperphosphorylated RAF1 [plasma membrane]

Stable Identifier
R-HSA-5675193
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-S29,S43,S259,S296,S301,S338,Y341,T491,S494,S621,S642 RAF1, RAF proto-oncogene serine/threonine-protein kinase , Raf-1, C-RAF, cRaf
hyperphosphorylated RAF1 [plasma membrane] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
RAF1, RAF
Chain
chain:1-648
Other Identifiers
11716472_a_at
11748273_a_at
16950848
1917_at
201244_s_at
2663243
2663245
2663246
2663247
2663248
2663251
2663253
2663258
2663261
2663263
2663270
2663271
2663272
2663273
2663274
2663275
2663278
2663279
2663280
2663281
2663282
2663283
2663284
2663292
38742_s_at
38743_f_at
5894
8085374
A_23_P40952
GE59649
GO:0000165
GO:0000166
GO:0000186
GO:0001666
GO:0001678
GO:0001934
GO:0002223
GO:0002376
GO:0003674
GO:0004672
GO:0004674
GO:0004709
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005794
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006810
GO:0006915
GO:0006950
GO:0007010
GO:0007165
GO:0007190
GO:0007267
GO:0007507
GO:0008150
GO:0008179
GO:0008219
GO:0008283
GO:0008285
GO:0009058
GO:0010856
GO:0015031
GO:0016020
GO:0016301
GO:0016310
GO:0016607
GO:0016740
GO:0017016
GO:0019899
GO:0022607
GO:0030154
GO:0030168
GO:0030234
GO:0030878
GO:0031143
GO:0031333
GO:0031434
GO:0033138
GO:0034220
GO:0034641
GO:0035019
GO:0035023
GO:0035556
GO:0035773
GO:0035994
GO:0040011
GO:0042060
GO:0042592
GO:0042802
GO:0042981
GO:0043066
GO:0043085
GO:0043154
GO:0043167
GO:0043226
GO:0044877
GO:0045104
GO:0045595
GO:0045944
GO:0046872
GO:0048011
GO:0048538
GO:0048856
GO:0048870
GO:0055085
GO:0060324
GO:0065003
GO:0071550
GO:1902042
GO:2000145
ILMN_1813489
PH_hs_0039978
TC03001174.hg
X03484_at
g4506400_3p_a_at
Participant Of
This entity regulates
Other forms of this molecule
Inferred To
Modified Residues
Name
O-phospho-L-serine at 621
Coordinate
621
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 341
Coordinate
341
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-serine at 338
Coordinate
338
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 491
Coordinate
491
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 494
Coordinate
494
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 29
Coordinate
29
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 43
Coordinate
43
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 259
Coordinate
259
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 296
Coordinate
296
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 301
Coordinate
301
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 642
Coordinate
642
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
GeneCards
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (48)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P01112 HRAS  23 0.975 25
 UniProt:P15056 BRAF  68 0.959 57
 UniProt:P63104 YWHAZ  2 0.957 18
 UniProt:Q02750 MAP2K1  27 0.955 37
 UniProt:P31946 YWHAB  1 0.934 20
 UniProt:Q04917 YWHAH  1 0.864 9
 UniProt:P01111 NRAS  25 0.861 8
 UniProt:P27348 YWHAQ  1 0.848 7
 UniProt:P04049 RAF1  54 0.811 6
 UniProt:P61981 YWHAG  1 0.802 6
 UniProt:Q16543 CDC37  1 0.773 6
 UniProt:P30086 PEBP1  1 0.758 10
 UniProt:P08238 HSP90AB1  6 0.758 5
 UniProt:P36507 MAP2K2  12 0.745 5
 UniProt:P31947 SFN  1 0.744 5
 UniProt:P62258 YWHAE  1 0.738 5
 UniProt:P01116-2 KRAS  8 0.676 3
 UniProt:Q3ZCQ8 TIMM50  1 0.659 6
 UniProt:Q13188 STK3  4 0.645 6
 UniProt:O43852 CALU  3 0.643 4
 UniProt:Q13418 ILK  1 0.643 3
 UniProt:P62834 RAP1A  4 0.623 2
 UniProt:P01116 KRAS  47 0.623 5
 UniProt:Q96S96 PEBP4      0.597 4
 UniProt:P31749 AKT1  13 0.589 2
 UniProt:Q92934 BAD  4 0.589 2
 UniProt:P11021 HSPA5  6 0.576 5
 UniProt:Q6TCH7 PAQR3  1 0.576 3
 UniProt:P32883 Kras  12 0.573 2
 UniProt:O95816 BAG2  1 0.564 3
 UniProt:Q13526 PIN1  2 0.564 2
 UniProt:P07900 HSP90AA1  8 0.564 3
 UniProt:Q13177 PAK2  11 0.558 2
 UniProt:O39474 O39474      0.556 4
 UniProt:P00533 EGFR  59 0.553 2
 UniProt:P49368 CCT3  1 0.547 5
 UniProt:Q13362 PPP2R5C  3 0.544 2
 UniProt:P67775 PPP2CA  4 0.544 2
 UniProt:P50990 CCT8  5 0.527 3
 UniProt:P10398 ARAF  4 0.527 3
 UniProt:P50402 EMD  3 0.527 2
 UniProt:Q99933 BAG1  1 0.508 2
 UniProt:P03495 NS1      0.508 2
 UniProt:P43246 MSH2  3 0.508 2
 UniProt:P01120  3 0.499 2
 UniProt:P28301  3 0.499 2
 UniProt:Q9ESN9-2 MAPK8IP3      0.499 2
 UniProt:P05783 KRT18  1 0.488 5
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