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DUSP8 [nucleoplasm]
Stable Identifier
R-HSA-5675349
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF-independent MAPK1/3 activation (Homo sapiens)
Nuclear DUSPs dephosphorylate MAPKs (Homo sapiens)
nuclear MAPK DUSPs [nucleoplasm] (Homo sapiens)
DUSP8 [nucleoplasm] (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
Negative regulation of MAPK pathway (Homo sapiens)
Nuclear DUSPs dephosphorylate MAPKs (Homo sapiens)
nuclear MAPK DUSPs [nucleoplasm] (Homo sapiens)
DUSP8 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13202 DUSP8
Gene Names
DUSP8, C11orf81, VH5
Chain
chain:1-625
Reference Genes
BioGPS Gene:1850 DUSP8
COSMIC (genes):DUSP8 DUSP8
CTD Gene:1850 DUSP8
dbSNP Gene:1850 DUSP8
ENSEMBL:ENSG00000184545 DUSP8
HGNC:3074 DUSP8
KEGG:hsa:1850 DUSP8
Monarch:1850 DUSP8
NCBI Gene:1850 DUSP8
OMIM:602038 DUSP8
UCSC:Q13202 DUSP8
Reference Transcript
RefSeq:NM_004420.2 DUSP8
RefSeq:XM_011519933.2 DUSP8
RefSeq:XM_011519932.2 DUSP8
Other Identifiers
11755931_a_at
11758143_s_at
11758684_x_at
1561_at
1562_g_at
16734271
1850
206374_PM_at
206374_at
238594_PM_x_at
238594_x_at
3244902
3244943
3244946
3244951
3244959
3244969
3244973
3245063
3245603
3245604
3245605
3245614
3251821
3251823
3251827
3251837
3358855
3358856
3358857
3358858
3358859
3358860
3358861
3358862
3358863
3358864
3358865
3358866
3358868
3358869
3358870
3358871
3358873
3358874
3358875
3358878
46483_at
7945641
A_23_P390528
A_24_P322867
A_33_P3263625
A_33_P3359012
GE59040
GO:0003824
GO:0004721
GO:0004722
GO:0004725
GO:0005515
GO:0005634
GO:0005737
GO:0006470
GO:0008330
GO:0016311
GO:0016787
GO:0016791
GO:0017017
GO:0017018
GO:0033550
GO:0043226
GO:0043409
GO:0140096
HMNXSV003003020
HMNXSV003043918
Hs.107448.0.A1_3p_x_at
ILMN_1743204
PH_hs_0026661
TC11001260.hg
U27193_at
g4758211_3p_at
Participates
as a candidate of
nuclear MAPK DUSPs [nucleoplasm] (Homo sapiens)
Other forms of this molecule
DUSP8 [cytosol]
Inferred To
DUSP8 [nucleoplasm]
(Bos taurus)
DUSP8 [nucleoplasm]
(Canis familiaris)
DUSP8 [nucleoplasm]
(Dictyostelium discoideum)
DUSP8 [nucleoplasm]
(Gallus gallus)
DUSP8 [nucleoplasm]
(Plasmodium falciparum)
DUSP8 [nucleoplasm]
(Sus scrofa)
Homologues of DUSP8 [nucleoplasm]
(Dictyostelium discoideum)
mpl2 [nucleoplasm]
(Dictyostelium discoideum)
mpl1 [nucleoplasm]
(Dictyostelium discoideum)
dusp8a [nucleoplasm]
(Danio rerio)
Dusp8 [nucleoplasm]
(Mus musculus)
Dusp8 [nucleoplasm]
(Rattus norvegicus)
mpl3 [nucleoplasm]
(Dictyostelium discoideum)
Cross References
RefSeq
XP_011518234.1
,
NP_004411.2
,
XP_011518235.1
ENSEMBL
ENSP00000487093
,
ENST00000707551
,
ENSP00000380530
,
ENSP00000479946
,
ENST00000625578
,
ENST00000707550
,
ENSP00000481775
,
ENSP00000487017
,
ENST00000617829
,
ENST00000610856
,
ENST00000629053
,
ENSP00000329539
,
ENSP00000516910
,
ENST00000331588
,
ENST00000397374
,
ENSP00000516909
OpenTargets
ENSG00000184545
HPA
ENSG00000184545-DUSP8
PRO
Q13202
Pharos - Targets
Q13202
HMDB Protein
HMDBP08915
PDB
4JMK
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P45983 MAPK8
3
MAPK8 [cytosol]
(R-HSA-168141)
p-T,Y-MAPK8 [cytosol]
(R-HSA-194371)
p-T,Y-MAPK8 [nucleoplasm]
(R-HSA-216349)
0.659
3
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