Reactome: A Curated Pathway Database

PP5 dephosphorylates RAF1 S338

Stable Identifier
R-HSA-5675433
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

PPP5C dephosphorylates S338 in the NtA region of RAF1, which reduces the catalytic activity of RAF1 towards MAP2K proteins (von Kriegsheim et al, 2006; reviewed in Matallanas et al, 2011).

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein serine/threonine phosphatase activity of PPP5C [cytosol] PPP5C [cytosol] protein serine/threonine phosphatase activity (0004722)
Orthologous Events