Reactome: A Curated Pathway Database

TNFSF18 binds TNFRSF18

Stable Identifier
R-HSA-5675947
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is a cytokine that regulates T-cell receptor-mediated cell death and promotes leukocyte adhesion to endothelial cells. It binds to tumor necrosis factor receptor superfamily member 18 (TNFRSF18 aka GITR) (Gurney et al. 1999).

Literature References
Participants
Participant Of
Orthologous Events