TNFSF18 binds TNFRSF18

Stable Identifier
R-HSA-5675947
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is a cytokine that regulates T-cell receptor-mediated cell death and promotes leukocyte adhesion to endothelial cells. It binds to tumor necrosis factor receptor superfamily member 18 (TNFRSF18 aka GITR) (Gurney et al. 1999).

Literature References
PubMed ID Title Journal Year
10074428 Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR

Gurney, AL, Marsters, SA, Huang, RM, Pitti, RM, Mark, DT, Baldwin, DT, Gray, AM, Dowd, AD, Brush, AD, Heldens, AD, Schow, AD, Goddard, AD, Wood, WI, Baker, KP, Godowski, PJ, Ashkenazi, A

Curr. Biol. 1999
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