KCNJ11:ABCC9 transports K+ from extracellular region to cytosol

Stable Identifier
R-HSA-5678261
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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ATP-sensitive inward rectifier potassium channel 11 (KCNJ11) is an inward rectifier potassium channel, favouring potassium flow into the cell rather than out of it. KCNJ11 can complex with ATP-binding cassette sub-family member 9 (ABCC9) to form cardiac and smooth muscle-type K+(ATP) channels. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (Babenko et al. 1998, Tammaro & Ashcroft 2007).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
inward rectifier potassium channel activity of KCNJ11:ABCC9 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created