CFTR G542* [plasma membrane]

Stable Identifier
R-HSA-5678986
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Cystic fibrosis transmembrane conductance regulator, CFTR_HUMAN
CFTR G542* [plasma membrane] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
CFTR, ABCC7
Chain
chain:1-1480
Reference Transcript
Other Identifiers
1080
11722757_at
17050697
205043_at
215702_s_at
3020647
3020648
3020652
3020654
3020658
3020659
3020661
3020662
3020663
3020664
3020666
3020667
3020668
3020670
3020672
3020673
3020674
3020679
3020680
3020682
3020683
3020684
3020685
3020686
3020688
3020689
3020694
3020695
3020696
3020698
3020699
3020701
3020702
3020705
3020706
3020707
3020712
3020719
3020721
3020722
3020723
3020724
3020725
3020726
3020727
36816_s_at
36817_at
3902164
3902300
8135661
A_14_P104877
A_14_P114787
A_14_P129538
A_14_P132049
A_23_P215720
GE62403
GO:0000003
GO:0000166
GO:0003674
GO:0005254
GO:0005260
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005769
GO:0005773
GO:0005783
GO:0005789
GO:0005829
GO:0005886
GO:0005887
GO:0006464
GO:0006629
GO:0006695
GO:0006810
GO:0006811
GO:0006821
GO:0006904
GO:0006914
GO:0006950
GO:0007267
GO:0008150
GO:0009056
GO:0009058
GO:0009986
GO:0010008
GO:0015031
GO:0015106
GO:0015108
GO:0015701
GO:0016020
GO:0016021
GO:0016192
GO:0016324
GO:0016579
GO:0016853
GO:0016887
GO:0019869
GO:0019899
GO:0021700
GO:0022857
GO:0030154
GO:0030165
GO:0030301
GO:0030660
GO:0030669
GO:0031410
GO:0031901
GO:0032991
GO:0034707
GO:0034976
GO:0035377
GO:0035774
GO:0035973
GO:0042592
GO:0042626
GO:0043167
GO:0043226
GO:0044281
GO:0045921
GO:0048240
GO:0048856
GO:0050891
GO:0051087
GO:0051454
GO:0055037
GO:0055038
GO:0055085
GO:0060081
GO:0061024
GO:0071320
GO:0106138
GO:1902161
GO:1902476
GO:1902943
GO:1904322
HMNXSV003020096
Hs.663.1.A1_3p_a_at
ILMN_1705813
M55131_at
PH_hs_0024884
TC07000726.hg
g6995995_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
glycine 542 replaced with unknown
Coordinate
542
PsiMod
A protein modification that effectively removes or replaces an glycine.
Disease
Name Identifier Synonyms
cystic fibrosis DOID:1485 mucoviscidosis, CF
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
707
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
IntEnz
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (171)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O14745 NHRF1      0.905 15
 UniProt:Q15599 NHRF2      0.869 14
 UniProt:P30153 PPP2R1A  2 0.813 11
 UniProt:P27824 CANX  2 0.813 14
 UniProt:Q9HD26 GOPC  3 0.71 4
 UniProt:Q5T2W1 NHRF3      0.702 6
 UniProt:P13569 CFTR  17 0.702 12
 UniProt:P60709 ACTB  5 0.669 5
 UniProt:P02545 LMNA  3 0.643 13
 UniProt:P31689 DNAJA1  1 0.643 13
 UniProt:P31151 S100A7  2 0.643 10
 UniProt:P28799 GRN  2 0.643 11
 UniProt:Q13200 PSMD2  5 0.643 11
 UniProt:P06702 S100A9  3 0.643 10
 UniProt:Q15370 ELOB  2 0.643 12
 UniProt:P11021 HSPA5  6 0.643 11
 UniProt:Q14974 KPNB1  5 0.643 11
 UniProt:Q15369 ELOC  2 0.643 7
 UniProt:P13987 CD59  8 0.643 9
 UniProt:O15554 KCNN4  1 0.602 5
 UniProt:P15311 EZR  3 0.597 10
 UniProt:P05787 KRT8  1 0.589 7
 UniProt:Q9HBW0 LPAR2  1 0.558 4
 UniProt:Q9JIL4 NHRF3      0.544 7
 UniProt:Q9H8Y8 GORASP2  2 0.544 3
 UniProt:Q9QX74 SHAN2      0.544 2
 UniProt:Q99942 RNF5  1 0.537 3
 UniProt:O00571 DDX3X  3 0.527 10
 UniProt:P55290 CDH13  1 0.527 7
 UniProt:P13010 XRCC5  4 0.527 9
 UniProt:O00299 CLIC1      0.527 9
 UniProt:Q5T4S7 UBR4  5 0.527 9
 UniProt:Q9Y608 LRRF2      0.527 7
 UniProt:P05109 S100A8  3 0.527 7
 UniProt:O43852 CALU  3 0.527 2
 UniProt:P22087 FBL  1 0.527 9
 UniProt:P56537 IF6      0.527 7
 UniProt:Q96CS3 FAF2  3 0.527 3
 UniProt:P62826 RAN  2 0.527 10
 UniProt:P61978 HNRNPK  2 0.527 10
 UniProt:Q6PID8 KLD10      0.527 5
 UniProt:P61619 SEC61A1  2 0.527 5
 UniProt:P00338 LDHA  1 0.527 10
 UniProt:P04899 GNAI2  1 0.527 8
 UniProt:P55060 XPO2      0.527 11
 UniProt:O75340 PDCD6      0.527 2
 UniProt:P30041 PRDX6  3 0.527 5
 UniProt:Q9NQH7 XPP3      0.527 6
 UniProt:P61160 ACTR2  4 0.527 10
 UniProt:P12956 XRCC6  5 0.527 9
 UniProt:P61163 ACTR1A  1 0.527 3
 UniProt:P0CG39 POTEJ      0.527 9
 UniProt:P19474 TRIM21  1 0.527 10
 UniProt:P08107 HSP71      0.527 4
 UniProt:Q8WWM7 ATX2L      0.527 2
 UniProt:A8MQ03 CRTP1      0.527 3
 UniProt:A0FGR8 ESYT2  1 0.527 4
 UniProt:P07814 EPRS1  1 0.527 3
 UniProt:P60981 DEST      0.527 9
 UniProt:P07947 YES1  2 0.527 6
 UniProt:Q08211 DHX9  2 0.527 10
 UniProt:Q92747 ARPC1A  1 0.527 10
 UniProt:Q9NYL9 TMOD3  1 0.527 10
 UniProt:Q9ULV4 COR1C      0.527 10
 UniProt:Q15393 SF3B3  1 0.527 9
 UniProt:P62873 GNB1  5 0.527 10
 UniProt:P40227 CCT6A  1 0.527 5
 UniProt:P62910 RPL32  1 0.527 9
 UniProt:Q96N67 DOCK7  1 0.527 7
 UniProt:P62191 PSMC1  2 0.527 10
 UniProt:P13667 PDIA4      0.527 9
 UniProt:O95433 AHSA1      0.527 4
 UniProt:P06748 NPM1  10 0.527 10
 UniProt:Q9Y678 COPG1  4 0.527 9
 UniProt:Q9UKM9 RALY      0.527 8
 UniProt:O60884 DNAJA2  1 0.527 4
 UniProt:P62879 GNB2  4 0.527 9
 UniProt:P04843 RPN1  1 0.527 9
 UniProt:P31040 SDHA  1 0.527 8
 UniProt:P17812 CTPS1  1 0.527 10
 UniProt:P17655 CAPN2  2 0.527 10
 UniProt:O95425 SVIL      0.527 9
 UniProt:P49368 CCT3  1 0.527 6
 UniProt:P50991 CCT4  1 0.527 8
 UniProt:Q9P035 HACD3  1 0.527 4
 UniProt:P05783 KRT18  1 0.527 9
 UniProt:Q5EB52 MEST      0.527 9
 UniProt:P06753 TPM3  3 0.527 11
 UniProt:Q15233 NONO      0.527 10
 UniProt:P46779 RPL28  1 0.527 9
 UniProt:Q9BUF5 TUBB6  6 0.527 8
 UniProt:P56192 MARS1  1 0.527 8
 UniProt:P04075 ALDOA  6 0.527 9
 UniProt:P49023 PXN  4 0.527 9
 UniProt:Q9BU76 MMTAG2  3 0.527 6
 UniProt:P50402 EMD  4 0.527 2
 UniProt:P46783 RPS10  2 0.527 9
 UniProt:Q8WWI1 LMO7  3 0.527 9
 UniProt:P47914 RPL29  1 0.527 10
 UniProt:Q9UL46 PSME2  2 0.527 9
 UniProt:Q9UJW0 DCTN4  1 0.527 5
 UniProt:P62841 RPS15  2 0.527 9
 UniProt:Q9UHB6 LIMA1      0.527 9
 UniProt:P37802 TAGLN2  2 0.527 10
 UniProt:P04080 CSTB  4 0.527 9
 UniProt:P31944 CASP14  2 0.527 6
 UniProt:Q9Y3U8 RPL36  1 0.527 7
 UniProt:Q12904 AIMP1  1 0.527 8
 UniProt:P52597 HNRNPF  2 0.527 2
 UniProt:Q9P2E9 RRBP1  2 0.527 4
 UniProt:Q13155 AIMP2  1 0.527 10
 UniProt:P04632 CAPNS1  2 0.527 4
 UniProt:P57088 TMM33      0.527 11
 UniProt:P35232 PHB  2 0.527 9
 UniProt:Q9BR76 COR1B      0.527 4
 UniProt:O00622 CCN1  2 0.527 10
 UniProt:P53618 COPB1  8 0.527 3
 UniProt:P22061 PCMT1  1 0.527 11
 UniProt:P09382 LGALS1  2 0.527 10
 UniProt:P62273 RPS29  2 0.527 9
 UniProt:P16615 ATP2A2  2 0.527 3
 UniProt:P27348 YWHAQ  1 0.527 10
 UniProt:Q14257 RCN2      0.527 10
 UniProt:Q14498 RBM39      0.527 10
 UniProt:Q9BQE3 TUBA1C  9 0.527 6
 UniProt:Q14254 FLOT2  1 0.527 9
 UniProt:Q13045 FLII      0.527 7
 UniProt:Q9UN37 VPS4A  1 0.527 2
 UniProt:O14980 XPO1  2 0.527 12
 UniProt:P50454 SERPINH1  1 0.527 10
 UniProt:P07910 HNRNPC  3 0.527 6
 UniProt:P06733 ENO1  1 0.527 9
 UniProt:P63000 RAC1  6 0.527 9
 UniProt:Q06830 PRDX1  3 0.527 10
 UniProt:P47897 QARS1  2 0.527 8
 UniProt:P20700 LMNB1  8 0.527 10
 UniProt:P63244 RACK1  1 0.527 9
 UniProt:P26599 PTBP1  1 0.527 7
 UniProt:P35579 MYH9  3 0.527 9
 UniProt:P04792 HSPB1  3 0.527 9
 UniProt:P26641 EEF1G  3 0.527 10
 UniProt:P54652 HSPA2  2 0.527 4
 UniProt:P14866 HNRNPL  1 0.527 9
 UniProt:P32119 PRDX2  2 0.527 9
 UniProt:P22626 HNRNPA2B1  2 0.527 10
 UniProt:P23246 SFPQ  3 0.527 10
 UniProt:P55072 VCP  8 0.527 7
 UniProt:Q08J23 NSUN2  1 0.527 9
 UniProt:O00410 IPO5  1 0.527 4
 UniProt:P10809 HSPD1  6 0.527 10
 UniProt:P38646 HSPA9  6 0.527 11
 UniProt:P08238 HSP90AB1  6 0.527 11
 UniProt:P14174 MIF  3 0.527 9
 UniProt:P78527 PRKDC  4 0.527 10
 UniProt:P05121 SERPINE1  4 0.527 10
 UniProt:P17987 TCP1  1 0.527 9
 UniProt:P67809 YBX1  2 0.527 10
 UniProt:P12004 PCNA  5 0.527 10
 UniProt:P31943 HNRNPH1  1 0.527 10
 UniProt:P63104 YWHAZ  2 0.527 10
 UniProt:P43490 NAMPT  1 0.527 10
 UniProt:P04637 TP53  20 0.527 10
 UniProt:O43852-1 CALU      0.524 2
 UniProt:P07384 CAPN1  4 0.499 3
 UniProt:P51790-2 CLCN3      0.499 2
 UniProt:Q9BUN8 DERL1  1 0.499 2
 UniProt:P11274 BCR  4 0.491 2
 UniProt:P16615-1 ATP2A2      0.471 6
 UniProt:Q7LBE3-1 SLC26A9      0.463 2
 UniProt:P51572 BCAP31  6 0.463 3
 UniProt:Q5XXA6 ANO1  1 0.463 2
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