LC3 family proteins are processed by members of the ATG4 family, which remove a C-terminal residue to create an exposed C-terminal glycine (Kirisako et al. 2000, Tanida et al. 2004, Kabeya et al. 2004, Li et al. 2011). Processed LC3 proteins are sometimes referred to as LC3-I.
Tanida, I, Sou, YS, Ezaki, J, Kominami, E, Minematsu-Ikeguchi, N, Ueno, T
Li, M, Chen, X, Hou, Y, Yin, XM, Shao, ZM, Wang, J
cysteine-type endopeptidase activity of ATG4 [cytosol]
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