Reactome: A Curated Pathway Database

MRN complex binds shortened telomeres

Stable Identifier
R-HSA-5682020
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The MRN complex (MRE11:RAD50:NBS1 also known as MRE11A:RAD50:NBN) binds telomeric DNA, and MRN association with telomeric DNA is mutually exclusive with shelterin binding (Wu et al. 2007).

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events