Reactome | BABAM1 [nucleoplasm]

BABAM1 [nucleoplasm]

Stable Identifier

R-HSA-5682582

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

BRISC and BRCA1-A complex member 1, NBA1, MERIT40

Locations in the PathwayBrowser for interactor UniProt:Q9NYB0%20TERF2IP

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External Reference Information

External Reference

UniProt:Q9NWV8 BABAM1

Gene Names

BABAM1, C19orf62, MERIT40, NBA1, HSPC142

Chain

chain:1-329

Reference Genes

BioGPS Gene:29086 BABAM1

COSMIC (genes):BABAM1 BABAM1

CTD Gene:29086 BABAM1

dbSNP Gene:29086 BABAM1

ENSEMBL:ENSG00000105393 BABAM1

ENSEMBL_homo_sapiens_GENE:ENSG00000105393.16 BABAM1

HGNC:25008 BABAM1

KEGG Gene (Homo sapiens):29086 BABAM1

Monarch:29086 BABAM1

NCBI Gene:29086 BABAM1

OMIM:612766 BABAM1

UCSC:Q9NWV8 BABAM1

Reference Transcript

Other Identifiers

11716039_a_at

11748858_a_at

16859454

221711_PM_s_at

221711_s_at

29086

3824154

3824155

3824157

3824158

3824159

3824160

3824161

3824162

3824163

3824165

3824169

3824170

3824172

3824175

3824176

3824177

46226_at

46227_at

8026698

91135_at

A_14_P124676

A_23_P119714

GE58566

GO:0000278

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006281

GO:0006282

GO:0006302

GO:0006325

GO:0006974

GO:0007049

GO:0007095

GO:0010212

GO:0016604

GO:0023052

GO:0030154

GO:0043226

GO:0044818

GO:0045739

GO:0048856

GO:0051301

GO:0070531

GO:0070552

GO:0071425

GO:0140861

HMNXSV003048773

ILMN_1806937

ILMN_2396813

PH_hs_0011206

TC19002626.hg

g13623286_3p_s_at

Participates

as an output of

as a component of

as an input of

Formation of BRCA1-A complex at DNA DSBs (Homo sapiens)

Other forms of this molecule

BABAM1 [cytosol]

Inferred To

BABAM1 [nucleoplasm] (Bos taurus)

BABAM1 [nucleoplasm] (Canis familiaris)

BABAM1 [nucleoplasm] (Gallus gallus)

BABAM1 [nucleoplasm] (Sus scrofa)

Babam1 [nucleoplasm] (Mus musculus)

Babam1 [nucleoplasm] (Rattus norvegicus)

babam1 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_001028721.1, NP_054892.2, NP_001275686.1, NP_001275685.1

OpenTargets

ENSG00000105393

HPA

ENSG00000105393-BABAM1

GeneCards

Q9NWV8

Ensembl

ENSP00000471605, ENSP00000470920, ENSP00000352408, ENSG00000105393, ENST00000601043, ENST00000598188, ENST00000359435

PRO

Q9NWV8

Pharos - Targets

Q9NWV8

PDB

6H3C

HMDB Protein

HMDBP13781

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NXR7 BRE	2	BRE [cytosol] (R-HSA-5691413) BRE [nucleoplasm] (R-HSA-5682579)	0.894	15
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.781	7
UniProt:Q9H2K2 TNKS2	1	TNKS2 [cytosol] (R-HSA-3640824)	0.688	5
UniProt:Q15018 FAM175B	1	FAM175B [cytosol] (R-HSA-5691428)	0.669	3
UniProt:Q6UWZ7 FAM175A	1	p-S406-FAM175A [nucleoplasm] (R-HSA-5682575)	0.564	2
UniProt:O95271 TNKS	1	TNKS [cytosol] (R-HSA-3640825)	0.564	2
UniProt:P34897 SHMT2	2	SHMT2 [cytosol] (R-HSA-9714752) PXLP-K280-SHMT2 [mitochondrial inner membrane] (R-HSA-5694086)	0.564	2
UniProt:Q9NYB0 TERF2IP	1	TERF2IP [nucleoplasm] (R-HSA-174873)	0.508	2
UniProt:P38398 BRCA1	20	polySUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624) monoSUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) BRCA1 M1411T [nucleoplasm] (R-HSA-9702140) BRCA1 M1400V [nucleoplasm] (R-HSA-9701202) BRCA1 L1407P [nucleoplasm] (R-HSA-9702135) BRCA1 Y777* [nucleoplasm] (R-HSA-9702765) BRCA1 S1009* [nucleoplasm] (R-HSA-9702755) BRCA1 P724Lfs12 [nucleoplasm] (R-HSA-9703778) BRCA1 S451 [nucleoplasm] (R-HSA-9702754) BRCA1 S864* [nucleoplasm] (R-HSA-9702752) BRCA1 P897Kfs5 [nucleoplasm] (R-HSA-9703782) BRCA1 N555Kfs17 [nucleoplasm] (R-HSA-9703781) BRCA1 Y1127Sfs6 [nucleoplasm] (R-HSA-9703780) BRCA1 S886Cfs16 [nucleoplasm] (R-HSA-9703802) BRCA1 V83Cfs2 [nucleoplasm] (R-HSA-9703800) BRCA1 T464Pfs11 [nucleoplasm] (R-HSA-9703807) BRCA1 G813Dfs2 [nucleoplasm] (R-HSA-9703549) BRCA1 V340Gfs6 [nucleoplasm] (R-HSA-9703804) BRCA1 Y655* [nucleoplasm] (R-HSA-9702769) BRCA1 W372* [nucleoplasm] (R-HSA-9702768)	0.483	2

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